J Korean Neurol Assoc.  2007 May;25(2):240-243.

A Case of Acute Respiratory Muscle Weakness Complicated by Sjogren Syndrome

Affiliations
  • 1Department of Neurology, Ajou University School of Medicine, Suwon, Korea.
  • 2Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 3Department of Neurology, National Health Insurance Coorporation Ilsan Hospital, Goyang, Korea.
  • 4Department of Neurology, National Medical Center, Seoul, Korea.
  • 5Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. kimsm@yumc.yonsei.ac.kr

Abstract

Sjogren syndrome is a chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands resulting in dry mouth and eyes. Approximately one-third of patients present with systemic manifestations, but respiratory muscle involvements have been rarely reported. We report a case of acute respiratory failure complicated by primary Sjogren syndrome. Muscle biopsy revealed perivascular lymphocytic infiltrations. Corticosteroid therapy improved respiratory muscle weakness. Sjogren syndrome should be considered as one of the underlying diseases causing acute respiratory failure.

Keyword

Sjogren syndrome; Respiratory paralysis; Myopathies

MeSH Terms

Autoimmune Diseases
Biopsy
Exocrine Glands
Humans
Mouth
Muscular Diseases
Respiratory Insufficiency
Respiratory Muscles*
Respiratory Paralysis
Sjogren's Syndrome*
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