Ann Clin Neurophysiol.  2023;25(1):41-44. 10.14253/acn.2023.25.1.41.

Overlap myositis associated with Sjögren's syndrome

• KMID: 2541822
• DOI: http://doi.org/10.14253/acn.2023.25.1.41

Abstract

Overlap myositis (OM) associated with Sjögren’s syndrome (SS) is a relatively uncommon disorder. It is more difficult to detect OM when a patient had not been previously diagnosed with SS. We report a case of OM associated SS that initially presented with dysphagia followed by proximal weakness. If proximal muscle weakness is preceded by dysphagia, the possibility of OM associated with connective-tissue disease should be considered.

Figure

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  Fig. 1. (A) Left submandibular gland echography indicating moderate-to-diffuse inhomogeneity with multiple hypoechoic area, which were grade 2 to 3 according to the outcome measures in rheumatology ultrasound scoring system for Sjögren's syndrome. (B) Enhanced chest CT revealed subpleural reticulations with consolidation and ground-glass opacity in both lower lobes. CT, computed tomography.

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  Fig. 2. (A, B, C, D) Fragments of skeletal muscular tissue indicating focal size variation in myofibers and mild lymphocytic infiltrates (×200, black arrows; A, H&E; B, LCA; C, CD4; D, CD8). H&E, hematoxylin and eosin; LCA, leukocyte common antigen.

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