Korean J Med Mycol.  2006 Sep;11(3):159-162.

A Case of Cutaneous Alternariosis in Liver Transplant Patient

Affiliations
  • 1Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. kwanglee@yumc.yonsei.ac.kr

Abstract

A case of cutaneous alternariosis is reported in a 61-year-old female who underwent liver transplantation one year earlier. The infection manifested as a crusted papule about 1 cm in diameter on the right knee. Histological examination with silver methenamine and periodic acid-Schiff diastase revealed fungal spores and hyphae with chronic granulomatous inflammation. Biopsy fragments inoculated on Sabouraud-glucose agar with chloramphenicol produced colonies which were identified as Alternaria species on the basis of macroscopic and microscopic characters. Complete excision and treatment with 250 mg/day oral terbinafine for one month resulted in a satisfactory course with no signs of local recurrence over follow-up period of one year.

Keyword

Cutaneous alternariosis; Immunosuppression; Liver transplantation

MeSH Terms

Agar
Alternaria
Alternariosis*
Amylases
Biopsy
Chloramphenicol
Female
Follow-Up Studies
Humans
Hyphae
Immunosuppression
Inflammation
Knee
Liver Transplantation
Liver*
Methenamine
Middle Aged
Recurrence
Spores, Fungal
Agar
Amylases
Chloramphenicol
Methenamine
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