Korean J Med Mycol.  2002 Sep;7(3):165-169.

A Case of Cutaneous Alternariosis

Affiliations
  • 1Department of Dermatology, Chosun University Medical School, Kwangju, Korea. bsjung@chosun.ac.kr

Abstract

Alternaria species are common plant pathogens and saprophytic fungi. Cutaneous alternariosis is rare and an opportunistic infection in both healthy and immunosuppressed hosts. We report a case of cutaneous alternariosis developed in a 60-year-old female with iatrogenic Cushing syndrome. She had several various sized confluent suppurative ulcers on erythematous plaques on the both forearm clinically. Histology showed mixed-cell granulomatous infiltration with epithelioid cells, lymphocytes, neutrophils and a few plasma cells in the dermis. Many branching septate hyphae and spores were noted within the granulomatous tissue stained with PAS. A fungal culture from biopsy specimen revealed Alternaria species; pigmented hyphae and cornidia which had both transverse and longitudinal septae. The cutaneous lesions treated with terbinafine, 250 mg daily, for 3 months and 1 year later there is no evidence of recurrence.

Keyword

Cutaneous alternariosis; Alternaria species

MeSH Terms

Alternaria
Alternariosis*
Biopsy
Cushing Syndrome
Dermis
Epithelioid Cells
Female
Forearm
Fungi
Humans
Hyphae
Immunocompromised Host
Lymphocytes
Middle Aged
Neutrophils
Opportunistic Infections
Plants
Plasma Cells
Recurrence
Spores
Ulcer
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