Korean J Dermatol.
2008 Sep;46(9):1236-1239.
Two Cases of Hand-Foot Syndrome Induced by Sunitinib
- Affiliations
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- 1Department of Dermatology, College of Medicine, Chungbuk National University, Cheongju, Korea. jyl@chungbuk.ac.kr
- 2Department of Urology, College of Medicine, Chungbuk National University, Cheongju, Korea.
Abstract
- Sunitinib (SU11248) is a novel orally administered small molecule that inhibits multiple receptor tyrosine kinases so that can block tumor growth and angiogenesis. It was approved on 2006, for the treatment of advanced renal cell carcinoma and gastrointestinal stromal tumor. Various cutaneous adverse reactions induced by sunitinib have been reported, including hand-foot syndrome. We report two cases of hand-foot syndrome induced by sunitinib for treatment of advanced renal cell carcinoma.
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