Korean J Dermatol.
2005 Jul;43(7):965-968.
Hand-foot Syndrome Due to Capecitabine
- Affiliations
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- 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
- 2Department of Dermatology, Seoul National University Bundang Hospital, Kyounggi, Korea. tigermed@hanafos.com
Abstract
- Hand-foot syndrome, also known as acral erythema, is a distinctive and relatively common toxic reaction due to some anticancer drugs. It is characterized by a painful erythema on the palms and soles during chemotherapy, which is often preceeded by paresthesia. We report two cases of hand-foot syndrome induced by capecitabine, which is a relatively brand-new oral anticancer agent. Hand-foot syndrome is one of the most common complications of capecitabine, and is on the increase. Therefore, dermatologists should be aware of it.
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