Korean J Dermatol.
2000 Apr;38(4):546-548.
Hand-Foot Syndrome with Nail Changes Induced by Fluorouracil
- Affiliations
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- 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
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Many chemotherapeutic agents induce both local and systemic cutaneous toxicity.
Among them, Fluorouracil (5-FU) induces various cutaneous reaction,
including hand-foot syndrome, hypersensitivity, hyperpigmentation and nail changes.
We describe a male patient with rectal cancer, who developed combined features of
hand-foot syndrome and nail changes during chemotherapy with 5-FU.