Infect Chemother.  2009 Aug;41(4):230-232. 10.3947/ic.2009.41.4.230.

Primary Anti-retroviral Resistance in Treatment-naive HIV-infected Patients: A Korean HIV/AIDS Cohort Study

Affiliations
  • 1Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. wjkim@medimail.co.kr
  • 2Division of Infectious Diseases, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.
  • 3Division of Infectious Diseases, Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.
  • 4Division of Infectious Diseases, Department of Internal Medicine, Ewha University College of Medicine, Seoul, Korea.
  • 5Division of Infectious Diseases, Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.

Abstract

Primary anti-retroviral resistance is considered one of the major problems of HIV treatment. Contrary to reports from western countries, prior Korean studies have reported a relatively low primary resistance rate (less than 5%). Based on Korean HIV/AIDS cohort data, we estimated the primary resistance rate among treatment-naive HIV-infected patients. According to the results, the primary resistance rate was higher (8.8%) than reported previously in Korean studies. However, the major PI mutation was not found.

Keyword

HIV; Antiretroviral therapy; Drug resistance

MeSH Terms

Cohort Studies
Drug Resistance
HIV
Humans

Cited by  2 articles

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