Korean J Med Phys.  2010 Dec;21(4):354-359.

The Dosimetric Effect on Real PTV and OARs at Various Image Fusion Protocol for Pituitary Adenomas

Affiliations
  • 1Department of Biomedical Engineering, The Catholic University of Korea College of Medicine, Seoul, Korea. suhsanta@catholic.ac.kr
  • 2Research Institute of Biomedical Engineering, The Catholic University of Korea College of Medicine, Seoul, Korea.
  • 3Department of Neurosurgery, College of Medicine, Inje University, Busan, Korea. djlee@paik.ac.kr

Abstract

The purpose of this study is to verify the dosimetric effect on real PTV (planning target volume) coverage and safety of OARs (organs at risk) at various image fusion protocol-based radiosurgery plan for pituitary adenomas. Real PTV coverage and its variation was acquired and maximum dose and the volume absorbing above threshold dose were also measured for verifying the safety of optic pathway and brainstem. The protocol that can reduce superior-inferior uncertainty by using both axial and coronal MR (magnetic resonance) image sets shows relatively lower values than that of case using only axial image sets. As a result, the image fusion protocol with both axial and coronal image sets can be beneficial to generate OAR-weighted radiosurgery plan.

Keyword

Pituitary adenomas; Image fusion protocol; PTV coverage; Safety of OARs

MeSH Terms

Brain Stem
Pituitary Neoplasms
Radiosurgery
Uncertainty
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