Korean J Pediatr.  2010 Dec;53(12):1006-1011. 10.3345/kjp.2010.53.12.1006.

What is the 'objective' differential factor of diarrhea in infancy?: Normal state versus diarrheal illness in infants with chronic frequent and loose stool

• Hwang JB
• Kang KJ
• Lee JJ
• Kim AS

• KMID: 1455876
• DOI: http://doi.org/10.3345/kjp.2010.53.12.1006

Abstract

PURPOSE
This study aimed to identify 'objective' differential factors for normal frequent loose stool (NFLS) and diarrheal illness with dehydration and nutritional deficiency (DIDN) among infants with chronic frequent loose stool (CFLS).
METHODS
Data were analyzed from infants under 2 years of age with CFLS who had been transferred from general pediatricians. These 46 patients were divided into 2 groups (NFLS versus DIDN). Nocturnal stool was defined as evacuation between 10 pm and 6 am. Maximal stool amount/day (measured using the mother's hand) was specified as the highest score during the period of CFLS obtained by adding up each evacuation's score (range, 0-2 points).
RESULTS
There were 36 cases of NFLS and 10 of DIDN. A failure to gain weight (P=0.0001), fever (P=0.0079), colic/abdominal pain (P=0.0014), gross blood in stool (except allergic proctocolitis) (P=0.0113), nocturnal stool (P=0.0001), and the score of stool amount (P=0.0001) were found to significantly differentiate the groups. A failure to gain weight was observed in 39% of even NFLS. The frequency, mucus content, and microbiological findings of stools, as well as diaper dermatitis were not found to significantly differentiate the groups.
CONCLUSION
NFLS was more common than DIDN in infants with CFLS. The most 'objective' differential factors were nocturnal stool and the score of stool amount (> or =7 points/day).

Keyword

Infant; Chronic disease; Diarrhea

MeSH Terms

Chronic Disease
Dehydration
Dermatitis
Diarrhea
Fever
Humans
Infant
Malnutrition
Mucus