Intest Res.  2011 Apr;9(1):57-60. 10.5217/ir.2011.9.1.57.

A Case of Angiosarcoma in Rectum

Affiliations
  • 1Department of Internal Medicine, Digestive Disease Research Institute, Wonkwang University School of Medicine, Iksan, Korea.
  • 2Department of Pathology, Wonkwang University School of Medicine, Iksan, Korea. kjyun@wonkwang.ac.kr
  • 3Department of Surgery, Wonkwang University School of Medicine, Iksan, Korea.

Abstract

Angiosarcoma is a malignant vascular neoplasm that usually involves the skin or soft tissues. A primary rectal angiosarcoma is exceedingly rare. A 77-year-old female was admitted to the hospital for evaluation of constipation and hematochezia. The patient had a history of uterine cervix carcinoma which was treated with surgery and radiation therapy. A colonoscopy revealed a friable, ulceroinfiltrative tumor with multiple hyperemic mucosae in the rectum. Microscopically, the tumor exhibited vasoformative growth with nuclear atypism and numerous mitoses. The tumor cells were strongly positive for CD31, CD34, and Factor VIII. We report a case of rectal angiosarcoma that developed after radiation therapy.

Keyword

Angiosarcoma; Rectum; Radiation

MeSH Terms

Aged
Cervix Uteri
Colonoscopy
Constipation
Factor VIII
Female
Gastrointestinal Hemorrhage
Hemangiosarcoma
Humans
Mitosis
Mucous Membrane
Rectum
Skin
Vascular Neoplasms
Factor VIII
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