Korean J Vet Res.  2011 Jun;51(2):171-175.

Malignant Sertoli cell tumor in Shih Tzu dog

Affiliations
  • 1College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 690-756, Korea. kimjhoon@jejunu.ac.kr
  • 2College of Veterinary Medicine, Gyeongsang National University, Jinju 660-701, Korea.
  • 3College of Life Science and Natural Resources, Sangji University, Wonju 220-702, Korea.

Abstract

Malignant Sertoli cell tumor was diagnosed in a 5-year-old male Shih Tzu dog. Clinical features of the dog were anorexia, urinary incontinence, constipation, anemia, alopecia, and epistaxis. The dog also had unilateral cryptorchid testis in the abdomen. Several abdominal and thoracic masses were identified on radiography. Grossly, the cryptorchid testicular mass was markedly enlarged to 8 cm in diameter. On cut surface, firm and well demarcated milk-white neoplastic areas were irregularly separated by white fibrous bands. Histologically, the testicular mass was diagnosed as tubular pattern Sertoli cell tumor. In addition, abdominal and mediastinal lymph nodes metastasis were found. Immunohistochemically, the tumor cells were strongly positive for vimentin and neuron specific enolase, but negative for S-100 and cytokeratin.

Keyword

cryptorchid testis; dog; immunohistochemistry; malignant Sertoli cell tumor

MeSH Terms

Abdomen
Alopecia
Anemia
Animals
Anorexia
Constipation
Dogs
Epistaxis
European Continental Ancestry Group
Humans
Immunohistochemistry
Keratins
Lymph Nodes
Male
Neoplasm Metastasis
Phosphopyruvate Hydratase
Preschool Child
Sertoli Cell Tumor
Testis
Urinary Incontinence
Vimentin
Keratins
Phosphopyruvate Hydratase
Vimentin
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