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Virulence genes of Streptococcus mutans and dental caries

You YO

Streptococcus mutans is one of the important bacteria that forms dental biofilm and cause dental caries. Virulence genes in S. mutans can be classified into the genes involved in bacterial...
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Assessment of serum biomarkers and coagulation/fibrinolysis markers for prediction of neurological outcomes of out of cardiac arrest patients treated with therapeutic hypothermia

Park JH, Wee JH, Choi SP, Oh JH, Cheol S

OBJECTIVE: Despite increased survival in patients with cardiac arrest, it remains difficult to determine patient prognosis at the early stage. This study evaluated the prognosis of cardiac arrest patients using...
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Combined Hepatocellular Carcinoma and Neuroendocrine Carcinoma with Ectopic Secretion of Parathyroid Hormone: A Case Report and Review of the Literature

Kwon HJ, Kim JW, Kim H, Choi Y, Ahn S

Primary combined hepatocellular carcinoma (HCC) and neuroendocrine carcinoma is a rare entity, and so is hypercalcemia due to ectopic parathyroid hormone (PTH) secretion by tumor. A 44-year-old man with hepatitis...
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Relationship between Serum Neuron Specific Enolase Level and Seizure in Patients with Acute Glufosinate Ammonium Poisoning

An GJ, Lee Y, Chan YS, Kim H

PURPOSE: Glufosinate ammonium poisoning can cause seizures, even after a symptom-free period. This study was conducted to evaluate the relationship between serum neuron specific enolase (NSE) level and the occurrence...
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Serum neuron specific enolase is increased in pediatric acute encephalitis syndrome

Pratamastuti D, Indra Gunawan P, Saharso D

PURPOSE: This study aimed to investigate whether serum neuron-specific enolase (NSE) was expressed in acute encephalitis syndrome (AES) that causes neuronal damage in children. METHODS: This prospective observational study was conducted...
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Overexpression of Neuron-Specific Enolase as a Prognostic Factor in Patients with Gastric Cancer

Park T, Lee YJ, Jeong SH, Choi SK, Jung EJ, Ju YT, Jeong CY, Park M, Hah YS, Yoo J, Ha WS, Hong SC, Ko GH

PURPOSE: Enolase is a cytoplasmic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway. The aim of this study was to investigate whether the overexpression of...
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Clinical Significance of Pretreatment FDG PET/CT in MIBG-Avid Pediatric Neuroblastoma

Kang SY, Rahim MK, Kim YI, Cheon GJ, Kang HJ, Shin HY, Kang KW, Chung JK, Kim EE, Lee DS

PURPOSE: ¹⁸F-fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging is well known to have clinical significance in the initial staging and response evaluation of the many kinds of neoplasms. However, its role in...
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Lentivirus-mediated microRNA-124 gene-modified bone marrow mesenchymal stem cell transplantation promotes the repair of spinal cord injury in rats

Song JL, Zheng W, Chen W, Qian Y, Ouyang YM, Fan CY

Our study aims to explore the effects of lentivirus-mediated microRNA-124 (miR-124) gene-modified bone marrow mesenchymal stem cell (BMSC) transplantation on the repair of spinal cord injury (SCI) in rats. BMSCs...
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Immunohistochemical localization of neuron specific enolase in developing tongue of Korean native goat (Capra hircus)

Cho G, Kim M, Lee S, Kim C, Won C

Neuron-specific enolase (NSE), a brain specific isoenzyme of the glycolytic enzyme, is characterized by its consistent occurrence in the cytoplasm of mature neurons. The purpose of the present study was...
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Neuron-specific enolase as a novel biomarker reflecting tuberculosis activity and treatment response

Nam SJ, Jeong JY, Jang TW, Jung MH, Chun BK, Cha HJ, Oak CH

BACKGROUND/AIMS: It is not clear which tests are indicative of the activity and severity of tuberculosis (TB). This study aimed to investigate the predictive value of neuron-specific enolase (NSE) and...
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Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells

Song H, Yoon SP, Kim J

After renal injury, selective damage occurs in the proximal tubules as a result of inhibition of glycolysis. The molecular mechanism of damage is not known. Poly(ADP-ribose) polymerase (PARP) activation plays...
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Cellular Neurothekeoma of the Scalp in the Elderly

Park MC, Seung WB

Cellular neurothekeoma (CNT) is an uncommon variant of neurothekeoma that is composed of pithelioid to spindled cells with variable nuclear atypia or pleomorphism but no myxoid stroma. CNT occurs predominantly...
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Non-Paraneoplastic Autoimmune Retinopathy: The First Case Report in Korea

Choi EY, Kim M, Adamus G, Koh HJ, Lee SC

Autoimmune retinopathy (AIR) is an immune-mediated retinopathy, resulting from an immunologic process caused by the aberrant recognition of retinal antigens as autoantigens. The diagnosis of AIR involves the detection of...
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Curcumin attenuates the middle cerebral artery occlusion-induced reduction in gamma-enolase expression in an animal model

Gim SA, Lee SR, Shah FA, Koh PO

Curcumin exerts a protective effect in cerebral ischemia through its anti-oxidant and anti-inflammatory activities. gamma-enolase is a glycolytic enzyme expressed in neurons that is known to exerts a neuroprotective effect....
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A Gene and Neural Stem Cell Therapy Platform Based on Neuronal Cell Type-Inducible Gene Overexpression

Oh J, You Y, Yun Y, Lee HL, Yoon DH, Lee M, Ha Y

PURPOSE: Spinal cord injury (SCI) is associated with permanent neurological damage, and treatment thereof with a single modality often does not provide sufficient therapeutic outcomes. Therefore, a strategy that combines...
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Performance Evaluation of the Elecsys Neuron-Specific Enolase Assay

Kim SK, Jeong TD, Lee W, Chun S, Min WK

BACKGROUND: Neuron-specific enolase (NSE) is an enzyme specifically found in neurons and neuroendocrine tissue. It is a common marker for small cell lung cancer diagnosis and is also useful as...
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Innervation of submandibular and sublingual glands in elderly donated cadavers: a preliminary histological study of differences in nerve morphology between mucous and serous acini

Asakawa S, Yamamoto M, Katori Y, Murakami G, Kasahara M, Matsunaga , Abe SI

We examined morphological differences between the sublingual and submandibular glands with special reference to their innervation. The sublingual gland contained abundant periodic acid Schiff-positive mucous acini: some lobules were composed...
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A Case of Small Cell Lung Carcinoma with Coexisting Autoantibodies against Proliferating Cell Nuclear Antigen and Centriole Detected Using the Autoimmune Target Test

Lee ZY, Kim TY

Approximately 60-70% of small cell lung carcinoma (SCLC) cases are diagnosed at extensive stage, thus tumor markers for its early detection are needed. Autoantibodies associated with malignancy are present before...
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Chondroid Syringoma: Clinical, Pathological, and Immunohistochemical Study of 23 Cases

Hwang SR, Park J, Yun SK, Kim HU, Roh SG

  • KMID: 1796720
  • Korean J Dermatol.
  • 2014 May;52(5):302-313.
BACKGROUND: Chondroid syringoma is a rare benign tumor composed of epithelial and stromal elements. Studies of chondroid syringoma are lacking in Korea and controversy still exists regarding the stromal cell...
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Metabolic Burden Measured by 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Is a Prognostic Factor in Patients with Small Cell Lung Cancer

Kim MH, Lee JS, Mok JH, Lee K, Kim KU, Park HK, Kim SJ, Lee MK

  • KMID: 2167679
  • Cancer Res Treat.
  • 2014 Apr;46(2):165-171.
PURPOSE: Evidence regarding the usefulness of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in predicting the prognosis of non-small cell lung cancer is increasing. However, data on small cell lung...
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