Korean J Pathol.  2012 Aug;46(4):392-394. 10.4132/KoreanJPathol.2012.46.4.392.

Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report

• Son C
• Choi PJ
• Roh MS

• KMID: 1439881
• DOI: http://doi.org/10.4132/KoreanJPathol.2012.46.4.392

Abstract

Primary liposarcoma of the lung is an extremely rare disease. To date, only 14 cases have been reported in the literature. We experienced a case of myxoid liposarcoma of the lung treated by surgery. The tumor was well-defined, solid, lobulated mass measuring 3.5x2 cm, involving the bronchus of the left lower lobe. Microscopically, myxoid liposarcoma was identified. The fluorescence in situ hybridization confirmed the presence of a reciprocal translocation involving DNA damage-inducible transcript 3 (DDIT3) and fused in sarcoma (FUS) genes. The patient is still alive with no recurrence or metastasis at the time of writing this report (on 20 months postoperatively). To our knowledge, this is the first cytogenetic case report of pulmonary myxoid liposarcoma.

Keyword

Lung; Liposarcoma; In situ hybridization, fluorescence

MeSH Terms

Bronchi
Cytogenetics
DNA
Female
Fluorescence
Humans
In Situ Hybridization
In Situ Hybridization, Fluorescence
Liposarcoma
Liposarcoma, Myxoid
Lung
Neoplasm Metastasis
Rare Diseases
Recurrence
Sarcoma
Writing
DNA