- Activated Protein C Protects Myocardium Via Activation of Anti-apoptotic Pathways of Survival in Ischemia-reperfused Rat Heart
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Ding JW, Tong XH, Yang J, Liu ZQ, Zhang Y, Yang J, Li S, Li L
- KMID: 1779231
- J Korean Med Sci.
- 2010 Nov;25(11):1609-1615.
- doi: 10.3346/jkms.2010.25.11.1609
Activated protein C (APC) is known to be beneficial on ischemia reperfusion injury in myocardium. However, the protection mechanism of APC is not fully understood. The purpose of this study... -
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- Cilostazol Protects Endothelial Cells Against Lipopolysaccharide-Induced Apoptosis Through ERK1/2- and P38 MAPK-Dependent Pathways
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Lim JH, Woo JS, Shin YW
- KMID: 1717961
- Korean J Intern Med.
- 2009 Jun;24(2):113-122.
- doi: 10.3904/kjim.2009.24.2.113
BACKGROUND/AIMS: We examined the effects of cilostazol on mitogen-activated protein kinase (MAPK) activity and its relationship with cilostazol-mediated protection against apoptosis in lipopolysaccharide (LPS)-treated endothelial cells. METHODS: Human umbilical vein... -
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- Exposure to Cerium Oxide Nanoparticles Is Associated With Activation of Mitogen-activated Protein Kinases Signaling and Apoptosis in Rat Lungs
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Rice KM, Nalabotu S, Manne ND, Kolli MB, Nandyala G, Arvapalli , Ma JY, Blough ER
- KMID: 2381462
- J Prev Med Public Health.
- 2015 May;48(3):132-141.
- doi: 10.3961/jpmph.15.006
OBJECTIVES: With recent advances in nanoparticle manufacturing and applications, potential exposure to nanoparticles in various settings is becoming increasing likely. No investigation has yet been performed to assess whether respiratory... -
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- Protective Effect of Ultra Low Molecular Weight Heparin on Glutamate-Induced Apoptosis in Cortical Cells
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Yu TG, Zhang QZ, Zhang ZG, Wang WW, Ji SL, Du GH
- KMID: 724266
- Yonsei Med J.
- 2008 Jun;49(3):486-495.
- doi: 10.3349/ymj.2008.49.3.486
PURPOSE: To investigate the effect of ultra low molecular weight heparin (ULMWH) on glutamate induced apoptosis in rat cortical cells and to explore the possible mechanisms. MATERIALS AND METHODS: Cell... -
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- The Effects of Family History of Colorectal Cancer on the Development of Colorectal Adenoma
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Choi MY, Kim BG, Kim JW, Lee KL, Jeong JB, Lee JK, Jung YJ, Kim W, Ahn DW, Kim YH, Joo SK, Chang MS, Kwon HJ
- KMID: 1718464
- Korean J Gastroenterol.
- 2012 Jul;60(1):36-41.
- doi: 10.4166/kjg.2012.60.1.36
BACKGROUND/AIMS: Early detection of polyp is important for the prevention of colorectal cancer (CRC). There have been few studies to investigate the relationship between colorectal adenoma and family history of... -
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- Toxoplasma gondi Inhibits Apoptosis in Infected Cells by Caspase Inactivation and NF-kappaB Activation
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Kim JY, Ahn MH, Jun HS, Jung JW, Ryu JS, Min DY
- KMID: 1777177
- Yonsei Med J.
- 2006 Dec;47(6):862-869.
- doi: 10.3349/ymj.2006.47.6.862
Our experiments aimed to clarify the mechanism by which host cell apoptosis is inhibited by infection with the intracellular protozoan parasite, Toxoplasma gondii (T. gondii). Mouse spleen cells were cultured... -
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- Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model
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Kim IH, Kim SW, Kim SH, Lee SO, Lee ST, Kim DG, Lee MJ, Park WH
- KMID: 1397449
- Exp Mol Med.
- 2012 Jul;44(7):448-456.
Parthenolide (PT), a sesquiterpene lactone derived from the plant feverfew, has pro-apoptotic activity in a number of cancer cell types. We assessed whether PT induces the apoptosis of hepatic stellate... -
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- Elm tree bark extract inhibits HepG2 hepatic cancer cell growth via pro-apoptotic activity
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Kim TM, Shin SK, Kim TW, Youm SY, Kim DJ, Ahn B
- KMID: 1364997
- J Vet Sci.
- 2012 Mar;13(1):7-13.
- doi: 10.4142/jvs.2012.13.1.7
Control of inflammation is widely accepted as an important strategy for cancer chemoprevention. Anti-inflammatory effects of bark extracts of elm tree (BEE) have been amply reported. Therefore, BEE may be... -
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- Telomerase and Apoptosis in the Placental Trophoblasts of Growth Discordant Twins
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Kim SY, Lee SP, Lee JS, Yoon SJ, Jun G, Hwang YJ
- KMID: 1381251
- Yonsei Med J.
- 2006 Oct;47(5):698-705.
- doi: 10.3349/ymj.2006.47.5.698
In an effort to investigate the molecular basis of growth discordance in embryos that experience the same uterine environment, we compared telomerase activity and apoptosis in placental trophoblasts obtained from... -
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- Human Telomerase Reverse Transcriptase (hTERT): A Target Molecule for the Treatment of Cisplatin-resistant Tumors
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Park YP, Kim KD, Kang SH, Yoon DY, Park JW, Kim JW, Lee HG
- KMID: 1781577
- Korean J Lab Med.
- 2008 Dec;28(6):430-437.
- doi: 10.3343/kjlm.2008.28.6.430
BACKGROUND: Human telomerase reverse transcriptase (hTERT) is a catalytic enzyme that is required for telomerase activity (TA) and cancer progression. Telomerase inhibition or inactivation increases cellular sensitivity to UV irradiation,... -
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