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The associations of tobacco use, sexually transmitted infections, HPV vaccination, and screening with the global incidence of cervical cancer: an ecological time series modeling study

Zheng L, Lin Y, Wu J, Zheng M

OBJECTIVES: We aimed to quantify the temporal associations between cervical cancer incidence and cervical cancer-related factors and to predict the number of new cervical cancer cases averted under counterfactual scenarios...
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Functional Regulation of Dopamine D₃ Receptor through Interaction with PICK1

Zheng M, Zhang X, Min C, Choi BG, Oh IJ, Kim KM

PICK1, a PDZ domain-containing protein, is known to increase the reuptake activities of dopamine transporters by increasing their expressions on the cell surface. Here, we report a direct and functional...
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Optimization of Submerged Fermentation Medium for Matrine Production by Aspergillus terreus, an Endophytic Fungus Harboring Seeds of Sophora flavescens, Using Response Surface Methodology

Zhang Q, Li Y, Xu F, Zheng M, Xi X, Zhang X, Han C

Different endophytes isolated from the seeds of Sophora flavescens were tested for their ability to produce matrine production. Response surface methodology (RSM) was applied to optimize the medium components for...
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Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors

Min C, Zhang X, Zheng M, Sun N, Acharya S, Zhang X, Kim KM

Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which...
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How to improve the survival rate of implants after radiotherapy for head and neck cancer?

Zheng M, Li L, Tang Y, Liang XH

Implants have been widely used in restorative treatment for patients who have undergone head and neck cancer surgery. With the development of combination treatment of head and neck cancer, radiotherapy...
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Effects of Endothelial Progenitor Cells Used for Autograft Transplantation in Acute Myocardial Infarction Pig Model

Wen D, Xu J, Huan Y, Wei M, Zheng M

Objective: Use magnetic resonance imaging (MRI) to explore the effects of superparamagnetic iron oxide (SPIO) nanoparticle-labeled endothelial progenitor cells (EPCs) in an acute myocardial infarction (AMI) pig model. Materials and Methods:...
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Mesenchymal stem cell-derived exosomes as a new therapeutic strategy for liver diseases

Lou G, Chen Z, Zheng M, Liu Y

The administration of mesenchymal stem cells (MSCs) as a therapy for liver disease holds great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote hepatic regeneration and secrete protective...
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Hair Growth Promotion by δ-Opioid Receptor Activation

Zheng M, Choi N, Balboni G, Xia Y, Sung JH

Literature has revealed that the delta opioid receptor (DOR) exhibited diverse pharmacological effects on neuron and skin. In the present study, we have investigated whether the activation of DOR has...
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CO/HO-1 Induces NQO-1 Expression via Nrf2 Activation

Kim HJ, Zheng M, Kim SK, Cho JJ, Shin CH, Joe Y, Chung HT

BACKGROUND: Carbon monoxide (CO) is a cytoprotective and homeostatic molecule with important signaling capabilities in physiological and pathophysiological situations. CO protects cells/tissues from damage by free radicals or oxidative stress....
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Circ_0068655 Promotes Cardiomyocyte Apoptosis via miR-498/ PAWR Axis

Chai Q, Zheng M, Wang Z, We M, Yin Y, Ma F, Li X, Zhang H, Liu G

BACKGROUND: The cardiomyocyte apoptosis is considered as one of major contributions to cardiac remodeling after myocardial infarction (MI). Numerous studies find that circular RNAs (circRNAs) play pivotal roles in a...
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Prevalence of Allergic Rhinitis Among Adults in Urban and Rural Areas of China: A Population-Based Cross-Sectional Survey

Zheng M, Wang X, Bo M, Wang K, Zhao Y, He F, Cao F, Zhang L, Bachert C

PURPOSE: The aim of the present study was to compare the prevalence of self-reported and confirmable allergic rhinitis (AR) with positive skin prick test (SPT) results among adults living in...
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Prevalence of feline calicivirus and the distribution of serum neutralizing antibody against isolate strains in cats of Hangzhou, China

Zheng M, Li Z, Fu X, Lv Q, Yang Y, Shi F

Background Feline calicivirus (FCV) is a common pathogen of felids, and FCV vaccination is regularly practiced. The genetic variability and antigenic diversity of FCV hinder the effective control and prevention of...
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Effects of 1,25-dihydroxyvitamin D₃ on the differentiation of MC3T3-E1 osteoblast-like cells

Kim HS, Zheng M, Kim DK, Lee WP, Yu SJ, Kim BO

PURPOSE: The purpose of this study was to evaluate the effects of 1,25-dihydroxyvitamin D₃ on the proliferation, differentiation, and matrix mineralization of MC3T3-E1 osteoblast-like cells in vitro. METHODS: MC3T3-E1 osteoblastic cells...
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Role of ATF on Transcriptional Regulation of DNA Topoisomerase II a Gene in HL - 60 Arrested to G2 / M and M Phase

Lim K, Son MY, Choi BI, Yun KA, Zheng M, Kang TW, Lee YC, Park JI, Yoon WH, Hwang BD

  • KMID: 2175140
  • J Korean Cancer Assoc.
  • 1999 Dec;31(6):1279-1287.
PURPOSE: To gain insight on transcriptional repression of Topo II a in HL-60 cells arrested to G2/M and M phase, the levels of Topo IIa mRNA and the binding activity...
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Stratified Treatment in Pediatric Anaplastic Large Cell Lymphoma: Result of a Prospective Open-Label Multiple-Institution Study

Chen T, Zeng C, Wang J, Sun F, Huang J, Zhu J, Lu S, Liao N, Zhang X, Chen Z, Yuan X, Yang Z, Guo H, Yang L, Wen C, Zhang W, Li Y, Luo X, Wu Z, Yang L, Liu R, Zheng M, He X, Sun X, Zhen Z

Purpose The risk stratification of pediatric anaplastic large cell lymphoma (ALCL) has not been standardized. In this study, new risk factors were included to establish a new risk stratification system...
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Chinese Society of Allergy and Chinese Society of Otorhinolaryngology-Head and Neck Surgery Guideline for Chronic Rhinosinusitis

Liu Z, Chen J, Cheng L, Li H, Liu S, Lou H, Shi J, Sun Y, Wang D, Wang C, Wang X, Wei Y, Wen W, Yang P, Yang Q, Zhang G, Zhang Y, Zhao C, Zhu D, Zhu L, Chen F, Dong Y, Fu Q, Li J, Li Y, Liu C, Liu F, Lu M, Meng Y, Sha J, She W, Shi L, Wang K, Xue J, Yang L, Yin M, Zhang L, Zheng M, Zhou B, Zhang L

The current document is based on a consensus reached by a panel of experts from the Chinese Society of Allergy and the Chinese Society of Otorhinolaryngology-Head and Neck Surgery, Rhinology...
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Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis

Cheng L, Chen J, Fu Q, He S, Li H, Liu Z, Tan G, Tao Z, Wang D, Wen W, Xu R, Xu Y, Yang Q, Zhang C, Zhang G, Zhang R, Zhang Y, Zhou B, Zhu D, Chen L, Cui X, Deng Y, Guo Z, Huang Z, Huang Z, Li H, Li J, Li W, Li Y, Xi L, Lou H, Lu M, Ouyang Y, Shi W, Tao X, Tian H, Wang C, Wang M, Wang N, Wang X, Xie H, Yu S, Zhao R, Zheng M, Zhou H, Zhu L, Zhang L

Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities worldwide. Epidemiologic studies have demonstrated that the prevalence of AR has increased progressively over the last...
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