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Zebrafish and Mycobacterial infection

Choi HY

  • KMID: 1598601
  • Korean Lepr Bull.
  • 2005 Jun;38(1):35-38.
The zebrafish emerged as a new model of developmental research and infection. Mycobacterium marinum naturally infects the zebrafish to develop the granuloma like tuberculosis. Also production of the protein of...
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Possibility of Zebrafish as New infection model for Leprosy

Kim JP, Choi HY, Cho SN

  • KMID: 1512597
  • Korean Lepr Bull.
  • 2006 Jun;39(1):37-48.
The zebrafish emerged as a new model of developmental research and infection. Recently zebrafish were used for various mycobacterial infection studies. In this study, we investigated a possibility of the...
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Electron-microscopic Findings of Elastic Fibers in Zebrafish Skin

Oh JE, Choi YW, Myung KB, Choi HY

  • KMID: 2247913
  • Korean J Dermatol.
  • 2009 Apr;47(4):379-385.
BACKGROUND: The zebrafish, Danio rerio, is a small bony fish that has genetic information and organ systems similar to those seen in human beings. The zebrafish has many advantages as...
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The Immunohistochemical Patterns of Calcification-related Molecules in the Epidermis and Dermis of the Zebrafish (Danio rerio)

Hong YJ, Choi YW, Myung KB, Choi HY

BACKGROUND: The scales of bony fish represent a significant reservoir of calcium and calcification of the elasmoid scale is known to be associated with deposition of mineral crystals from the...
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Evaluation of the Toxicity of Sugammadex in Zebrafish Larvae

Kim WY, Kim YH, Lee JY, Kim JH, Min TJ

BACKGROUND: Sugammadex is a new neuromuscular blockade reversal agent. Recently, it has been used in patients under general anesthesia. However, sugammadex could be toxic to fetuses and pediatric patients under...
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Induction of cell deathin early developmental phase of zebrafish treated with diethylnitrosamine

Kang JS

The purpose of this study was to investigate diethylnitrosamine (DEN)-induced liver damage in zebrafish. Zebrafish larvae were divided into five groups after seventy-two hours fertilization: group 1 (G1) as control,...
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Ultrastructure and Development of Heart Wall of Zebrafish (Danio rerio)

Kim HT, Chon SE, Kim H, Lee MS

  • KMID: 1578389
  • Korean J Phys Anthropol.
  • 2000 Mar;13(1):55-69.
Light and electron microscopic obserbations of developing heart wall of zebrafish, which has been recently used for developmental studies of many organs, were performed. Heart tissue was obtained from adult...
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AcuD Gene Knockout Attenuates the Virulence of Talaromyces marneffei in a Zebrafish Model

Feng J, Chen Z, He L, Xiao X, Chen C, Chu J, Mylonakis , Xi L

Talaromyces marneffei is the only dimorphic species in its genus and causes a fatal systemic mycosis named talaromycosis. Our previous study indicated that knockdown of AcuD gene (encodes isocitrate lyase...
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Functional Prediction of Imprinted Genes in Chicken Based on a Mammalian Comparative Expression Network

Kim HY, Moon S, Kim H

  • KMID: 2166319
  • Genomics Inform.
  • 2008 Mar;6(1):32-35.
Little evidence supports the existence of imprinted genes in chicken. Imprinted genes are thought to be intimately connected with the acquisition of parental resources in mammals; thus, the predicted lack...
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Microarray Screening for Genes Involved in Oligodendrocyte Differentiation in the Zebrafish CNS

Chung AY, Kim S, Kim H, Bae YK, Park HC

Within the vertebrate nervous system, myelination is required for the normal function of neurons by facilitating the rapid conduction of action potentials along axons. Oligodendrocytes are glial cells which myelinate...
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Effect of Adenosine on Melanogenesis in B16 Cells and Zebrafish

Kim MY, Lee HE, Im M, Lee Y, Kim CD, Lee JH, Seo YJ

BACKGROUND: Adenosine is a nucleoside, in which an adenine molecule is attached to a ribofuranose sugar moiety. It can be released into the microenvironment by metabolically active cells, and then...
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Influence of Pulse Type on Subcellular Selective Photothermolysis of Melanosomes in Adult Zebrafish Skin Following 1,064-nm, Q-switched, Nd:YAG Laser Irradiation: A Pilot Study

Yoo MG, So BJ, Lee JM, Kim DH, Park HC, Ryu HJ, Kim IH

No abstract available.
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Morphologic Changes of Zebrafish Melanophore after Intense Pulsed Light and Q-Switched Nd:YAG Laser Irradiation

Ryu HJ, Lee JM, Jang HW, Park HC, Rhyu IJ, Kim IH

BACKGROUND: Recently, the pulse-in-pulse mode of intense pulsed light (IPL) has been used increasingly for the treatment of melasma. OBJECTIVE: To observe the morphologic changes in the melanophore in adult zebrafish...
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Zebrafish Larvae Model of Dilated Cardiomyopathy Induced by Terfenadine

Gu G, Na Y, Chung H, Seok SH, Lee HY

BACKGROUND AND OBJECTIVES: Dilated cardiomyopathy can be the end-stage of severe cardiac disorders and directly affects the cardiac muscle, inducing cardiomegaly and heart failure (HF). Although a wide variety of...
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In vivo alternative testing with zebrafish in ecotoxicology

Seok SH, Baek MW, Lee HY, Kim DJ, Na YR, Noh KJ, Park SH, Lee HK, Lee BH, Park JH

Although rodents have previously been used in ecotoxicological studies, they are expensive, time-consuming, and are limited by strict legal restrictions. The present study used a zebrafish (Danio rerio) model and...
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Protective Role of Trimetazidine Against Neomycin-induced Hair Cell Damage in Zebrafish

Chang J, Im GJ, Chae SW, Lee SH, Kwon SY, Jung HH, Chung AY, Park HC, Choi J

  • KMID: 2278429
  • Clin Exp Otorhinolaryngol.
  • 2013 Dec;6(4):219-225.
OBJECTIVES: Trimetazidine (TMZ) is known to reduce the generation of oxygen-derived free radicals. The objective of the present study was to evaluate the effects of TMZ on neomycin-induced ototoxicity in...
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microRNA-183 is Essential for Hair Cell Regeneration after Neomycin Injury in Zebrafish

Kim CW, Han JH, Wu L, Choi JY

PURPOSE: microRNAs (miRNAs) are non-coding RNAs composed of 20 to 22 nucleotides that regulate development and differentiation in various organs by silencing specific RNAs and regulating gene expression. In the...
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Role of histone deacetylase activity in the developing lateral line neuromast of zebrafish larvae

He Y, Mei H, Yu H, Sun S, Ni W, Li H

Histone deacetylases are involved in many biological processes and have roles in regulating cell behaviors such as cell cycle entry, cell proliferation and apoptosis. However, the effect of histone deacetylases...
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The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway

Cheng Z, Zhang Q, Yin A, Feng M, Li H, Liu H, Li Y, Qian L

In a previous study, we screened thousands of long non-coding RNAs (lncRNAs) to assess their potential relationship with congenital heart disease (CHD). In this study, uc.4 attracted our attention because...
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Functional characterization of human oncoprotein gankyrin in Zebrafish

Kim SY, Hur W, Choi JE, Kim D, Wang JS, Yoon HY, Piao LS, Yoon SK

Gankyrin is an oncoprotein containing seven ankyrin repeats that is overexpressed in hepatocellular carcinoma (HCC). Gankyrin binds to Mdm2, which results in accelerated ubiquitylation via degradation of p53, and it...
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