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Effect of Bovine and Human Lactoferrin on MA 104 Cell Infected with Human Rotavirus

Cha KJ, Yu DY, Lee CK, Yu JH

  • KMID: 2096743
  • J Korean Soc Virol.
  • 1999 Jun;29(2):87-97.
It has long been known that lactoferrin prevents human beings from infection of virus. To prove this activity of lactoferrin, we evaluated the activities of different lactoferrins to an isolate...
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Serotype and Nucleotide Analysis of Human Rotavirus Isolates in Korea

Cha KJ, Song JO, Cho HC, Kim YH, Yu DY, Lee JB, Lee CK, Koki T, Yu JH

  • KMID: 2096742
  • J Korean Soc Virol.
  • 1999 Jun;29(2):75-86.
Rotaviruses belong to Reoviridae causes diarrhea in human beings as well as domestic animals. This study was conducted to see what type of human rotaviruses are distributed in Seoul and...
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Two base pair deletion in IL2 receptor γ gene in NOD/SCID mice induces a highly severe immunodeficiency

Bak I, Kim DJ, Kim HC, Shin HJ, Yu E, Yoo KW, Yu DY

Genome editing has recently emerged as a powerful tool for generating mutant mice. Small deletions of nucleotides in the target genes are frequently found in CRISPR/Cas9 mediated mutant mice. However,...
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Clinical significance of pancreatic intraepithelial neoplasia in resectable pancreatic cancer on survivals

Yu DY, Yu YD, Kim WB, Han HJ, Choi SB, Kim DS, Choi SY, Kim JY, Chang H, Kim BH

PURPOSE: Noninvasive precursor lesions for pancreatic adenocarcinoma include pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm, and mucinous cystic neoplasm. PanIN is often found synchronously adjacent to resected pancreatic ductal...
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Left paraduodenal hernia accompanying chylous ascites

Yu DY, Jang YJ, Mok YJ

Paraduodenal hernia is by far the most common form of congenital internal hernia. Chylous ascites is an accumulation of lymphatic fluid in the peritoneal cavity. It develops when the lymphatic...
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Transgenic expression of Korean type hepatitis C virus core protein and related mutants in mice

Wang AG, Moon HB, Lee YH, Yu SL, Kwon HJ, Han YH, Fang W, Lee TH, Jang KL, Kim SK, Yu DY, Lee DS

  • KMID: 1103328
  • Exp Mol Med.
  • 2004 Dec;36(6):588-592.
Hepatitis C virus (HCV) is a major causative agent in liver disease. In order to investigate if Korean type HCV core protein and its related mutants, S99Q and S116I, are...
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Comparison of robotic and laparoscopic lateral transperitoneal adrenalectomies

Ko SY, Chang YW, Ku D, Yu DY, Lee HY, Ji WB, Son GS

Purpose: This study aimed to compare the intraoperative and postoperative outcomes between robotic and laparoscopic transperitoneal adrenalectomies. Methods: In this retrospective study, 93 patients underwent adrenalectomy using 2 surgical modalities: 45...
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Expression of hepatitis C virus nonstructural 4B in transgenic mice

Wang AG, Moon HB, Kim JM, Hwang SB, Yu DY, Lee DS

  • KMID: 1094149
  • Exp Mol Med.
  • 2006 Jun;38(3):241-246.
Hepatitis C virus (HCV) is a pathogen that is of great medical significance in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. Although the HCV proteins have been intensively investigated...
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Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression

Hwang CY, Han YH, Lee SM, Cho SM, Yu DY, Kwon KS

Background: Sestrin2 (Sesn2) is involved in the maintenance of metabolic homeostasis and aging via modulation of the 5' AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) pathway. Methods: Wild-type and Sesn2...
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Relevance of reactive oxygen species in liver disease observed in transgenic mice expressing the hepatitis B virus X protein

Yu DY

The hepatitis B virus (HBV) infects approximately 240 million people worldwide, causing chronic liver disease (CLD) and liver cancer. Although numerous studies have been performed to date, unfortunately there is...
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An important role for peroxiredoxin II in survival of A549 lung cancer cells resistant to gefitinib

Kwon T, Rho JK, Lee JC, Park YH, Shin HJ, Cho S, Kang YK, Kim BY, Yoon DY, Yu DY

Redox adaptation is an important concept that explains the mechanisms by which cancer cells survive under persistent endogenous oxidative stress and become resistant to certain anticancer agents. To investigate this...
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Comparison of Single Incision Endoscopic Nipple-Sparing Mastectomy and Conventional NippleSparing Mastectomy for Breast Cancer Based on Initial Experience

Lee HY, Chang YW, Yu DY, Lee TY, Kim DW, Kim WY, Jung SP, Woo SU, Lee JB, Son GS

Purpose: Endoscopic breast surgery for patients with breast cancer was introduced for its superior cosmetic outcomes; it was initially studied in the field of breast-conserving surgery and, more recently, in...
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Membrane-type Matrix Metalloproteinase-1 Induced Invasive and Angiogenic Activities in Chick Chorioallantoic Membrane (CAM) Model

Jeong JW, Sohn TK, Yu DY, Kim KW

  • KMID: 2007126
  • J Korean Cancer Assoc.
  • 2001 Feb;33(1):49-55.
PURPOSE: Matrix metalloproteinases (MMPs) have been reported to play critical roles in the endothelial cell migration and matrix remodeling during angiogenic process. To investigate the roles of the membrane type...
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Pathologic Findings in the Liver of Hepatitis B Virus X Transgenic Mice

Moon HB, Yu DY, So BJ, Kim HC, Han WC, Yun KJ, Yoo HN

  • KMID: 2275538
  • Korean J Pathol.
  • 2003 Oct;37(5):342-350.
BACKGROUND: The aim of this study was to investigate the hepatic pathology of HBx transgenic mice. METHODS: The gross and histological examinations were done in 125 HBx transgenic mice and...
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A Study on the Expression of Proliferating Cell Nuclear Antigen and Apoptosis of the Hepatocellular Carcinoma in Human and Hepatitis B Virus X Transgenic Mice

Moon HB, Yu DY, Yoo HR, So BJ, Chae KM, Kim HC, Yun KJ, Han WC, Jo HJ, Kim BY

  • KMID: 2275643
  • Korean J Pathol.
  • 2001 Apr;35(2):129-136.
BACKGROUND: This experiment was designed to study the cell kinetics of hepatocellular carcinoma (HCC) in both hepatitis B virus X (HBx) transgenic mice and humans. METHODS: The immunohistochemical stain of...
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Studies on In Vivo Function of Peroxiredoxins in Knockout Mice

Yu DY

Peroxiredoxins (Prxs) are a family of antioxidant proteins that reduce peroxide levels by using reducing agents such as thioredoxin. These proteins were characterized to have a number of cellular functions,...
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Usefulness of High-Resolution Sonography for Assessement of Hepatocellular Carcinoma in the Transgenic Mice Expressing Hepatitis B Virus X-protein: A Preliminary Study

Yoon KH, Yu DY, Park SH, Kim CG, Won JJ, Moon HB

PURPOSE: To determine the value of high resolution ultrasonography (US) for the detection of hepatocellular carcinoma in the HBx transgenic mice. MATERIALS AND METHODS: Forty-two HBx transgenic mice aged 8-20...
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Baseline extent of damage predicts spinal radiographic progression in Korean patients with ankylosing spondylitis treated with golimumab

Lee JS, Song YW, Kim TH, Chung WT, Lee SG, Park SH, Song GG, Yu DY, Xu S, Lee EY

BACKGROUND/AIMS: For patients with ankylosing spondylitis (AS), golimumab has consistent efficacy in controlling disease activity over 5 years but its benefit in preventing radiographic progression was less clear at 4...
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Expression of Organic Anion Transporting Polypeptides in an H-Ras 12V Transgenic Mouse Model of Spontaneous Hepatocellular Carcinoma

Kim H, Choi J, Yu DY, Choi HJ

Purpose: Expression of organic anion transporting polypeptides (OATPs) 1B1/1B3 in hepatocellular carcinoma (HCC) induces a paradoxical enhancement of gadoxetic acid on liver magnetic resonance imaging (MRI). We examined the expression...
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Differences in Clinical Responses to Ustekinumab Treatment among Body Regions: Results from a Real-World Prospective, Observational, and Multi-Center Study in Korea

Son SW, Yu DY, Kim Y, Ahn HH, Jang YH, Roh JY, Lee YB, Lee JY, Kim MH, Lee Y, Park GH, Yoon HS, Youn SW, on behalf of the Stelara PMS investigators

Background: In psoriasis treatment, not all body regions improve simultaneously after clinical interventions. Objective: This study was aimed at evaluating clinical responses across body regions, which may differentially influence patient treatment...
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