- Decreased ARID1A expression is correlated with chemoresistance in epithelial ovarian cancer
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Yokoyama Y, Matsushita Y, Shigeto T, Futagami M, Mizunuma H
- KMID: 1811189
- J Gynecol Oncol.
- 2014 Jan;25(1):58-63.
- doi: 10.3802/jgo.2014.25.1.58
OBJECTIVE: Loss of ARID1A is related to oncogenic transformation of ovarian clear cell adenocarcinoma. The present study was conducted in epithelial ovarian cancer of all tissue types to investigate whether... -
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- Essential anatomy for lateral lymph node dissection
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Yokoyama Y, Nozawa H, Sasaki K, Murono K, Emoto S, Matsuzaki H, Abe S, Nagai Y, Yoshioka Y, Shinagawa T, Sonoda H, Hojo D, Ishihara S
- KMID: 2549559
- Ann Coloproctol.
- 2023 Dec;39(6):457-466.
- doi: 10.3393/ac.2023.00164.0023
In Western countries, the gold-standard therapeutic strategy for rectal cancer is preoperative chemoradiotherapy (CRT) following total mesorectal excision (TME), without lateral lymph node dissection (LLND). However, preoperative CRT has recently... -
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- Neuroendocrine carcinoma associated with chronic ulcerative colitis: a case report and review of the literature
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Yokota Y, Anzai H, Nagai Y, Sonoda H, Shinagawa T, Yoshioka Y, Abe S, Yokoyama Y, Matsuzaki H, Emoto S, Murono K, Sasaki K, Nozawa H, Ushiku T, Ishihara S
- KMID: 2556094
- Ann Coloproctol.
- 2024 May;40(Suppl 1):S32-S37.
- doi: 10.3393/ac.2022.00801.0114
Adenocarcinoma is a common histological type of ulcerative colitis-associated cancer (UCAC), whereas neuroendocrine carcinoma (NEC) is extremely rare. UCAC is generally diagnosed at an advanced stage, even with regular surveillance... -
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- Risk factors for non-reaching of ileal pouch to the anus in laparoscopic restorative proctocolectomy with handsewn anastomosis for ulcerative colitis
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Emoto S, Hata K, Nozawa H, Kawai K, Tanaka T, Nishikawa T, Shuno Y, Sasaki K, Kaneko M, Murono K, Iida Y, Ishii H, Yokoyama Y, Anzai H, Sonoda H, Ishihara S
- KMID: 2531985
- Intest Res.
- 2022 Jul;20(3):313-320.
- doi: 10.5217/ir.2020.00158
Background/Aims: Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis and handsewn anastomosis for ulcerative colitis requires pulling down of the ileal pouch into the pelvis, which can be technically challenging. We... -
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- Nutritional Status Indicators Affecting the Tolerability of Postoperative Chemotherapy After Total Gastrectomy in Patients With Gastric Cancer
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Toyota K, Mori M, Hirahara S, Yoshioka S, Kubota H, Yano R, Kobayashi H, Hashimoto Y, Sakashita Y, Yokoyama Y, Murakami Y, Miyamoto K
- KMID: 2535085
- J Gastric Cancer.
- 2022 Mar;22(1):56-66.
- doi: 10.5230/jgc.2022.22.e5
Purpose: Nutritional problems after gastrectomy affect continuation of postoperative chemotherapy. There have been no studies limited to total gastrectomy, which is particularly prone to nutritional problems. In this study, we... -
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- Impact of sarcopenia on biliary drainage during neoadjuvant therapy for pancreatic cancer
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Kataoka K, Ohno E, Ishikawa T, Yamao K, Mizutani Y, Iida T, Takami H, Maeda O, Yamaguchi J, Yokoyama Y, Ebata T, Kodera Y, Kawashima H
- KMID: 2551200
- Clin Endosc.
- 2024 Jan;57(1):112-121.
- doi: 10.5946/ce.2022.278
Background/Aims: Since the usefulness of neoadjuvant chemo(radiation) therapy (NAT) for pancreatic cancer has been demonstrated, recurrent biliary obstruction (RBO) in patients with pancreatic cancer with a fully covered self-expandable metal... -
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- Impact of COVID-19 on gynecologic cancer treatment in Japan: a nationwide survey by the Japan Society of Gynecologic Oncology (JSGO)
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Nogami Y, Komatsu H, Makabe T, Hasegawa Y, Yokoyama Y, Kawana K, Okamoto A, Mikami M, Katabuchi H, The COVID-19 Task Force of the Japan Society of Gynecologic Oncology
- KMID: 2536014
- J Gynecol Oncol.
- 2022 Jan;33(1):e8.
- doi: 10.3802/jgo.2022.33.e8
Objective As coronavirus disease 2019 (COVID-19) rages on, it is a challenging task to balance resources for treatment of COVID-19 and malignancy-based treatment. For the development of optimal strategies, assessing the... -
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- Adsorptive Granulocyte/Monocyte Apheresis for the Maintenance of Remission in Patients with Ulcerative Colitis: A Prospective Randomized, Double Blind, Sham-Controlled Clinical Trial
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Fukunaga K, Yokoyama Y, Kamokozuru K, Nagase K, Nakamura S, Miwa H, Matsumoto
- KMID: 2167411
- Gut Liver.
- 2012 Oct;6(4):427-433.
BACKGROUND/AIMS: Weekly granulocyte/monocyte adsorption (GMA) to deplete elevated and activated leucocytes should serve as a non-pharmacological intervention to induce remission in patients with ulcerative colitis (UC). This trial assessed the... -
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- The 2020 Japan Society of Gynecologic Oncology guidelines for the treatment of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer
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Tokunaga H, Mikami M, Nagase S, Kobayashi Y, Tabata T, Kaneuchi M, Satoh T, Hirashima Y, Matsumura N, Yokoyama Y, Kawana K, Kyo S, Aoki D, Katabuchi H
- KMID: 2526387
- J Gynecol Oncol.
- 2021 Mar;32(2):e49.
- doi: 10.3802/jgo.2021.32.e49
The fifth edition of the Japan Society of Gynecologic Oncology guidelines for the treatment of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer was published in 2020. The guidelines... -
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- Prevalence of Irritable Bowel Syndrome–like Symptoms in Japanese Patients with Inactive Inflammatory Bowel Disease
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Tomita T, Kato Y, Takimoto M, Yamasaki T, Kondo T, Kono T, Tozawa K, Yokoyama Y, Ikehara H, Ohda Y, Oshima T, Fukui H, Tanaka S, Shima M, Watari J, Miwa H
- KMID: 2433459
- J Neurogastroenterol Motil.
- 2016 Oct;22(4):661-669.
- doi: 10.5056/jnm15160
BACKGROUND/AIMS: Few studies are available that have investigated the risk factors for overlapping irritable bowel syndrome (IBS)-like symptoms in patients with inactive inflammatory bowel disease (IBD). The present study has... -
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- NUDT15, FTO, and RUNX1 genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases
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Sato T, Takagawa T, Kakuta Y, Nishio A, Kawai M, Kamikozuru K, Yokoyama Y, Kita Y, Miyazaki T, Iimuro M, Hida N, Hori K, Ikeuchi H, Nakamura S
- KMID: 2382376
- Intest Res.
- 2017 Jul;15(3):328-337.
- doi: 10.5217/ir.2017.15.3.328
BACKGROUND/AIMS: Recent genome-wide analyses have provided strong evidence concerning adverse events caused by thiopurine drugs such as azathioprine (AZA) and 6-mercaptopurine. The strong associations identified between NUDT15 p.Arg139Cys and thiopurine-induced... -
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- Infliximab Therapy Impacts the Peripheral Immune System of Immunomodulator and Corticosteroid Naive Patients with Crohn's Disease
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Kato K, Fukunaga K, Kamikozuru K, Kashiwamura S, Hida N, Ohda Y, Takeda N, Yoshida K, Iimuro M, Yokoyama Y, Kikuyama R, Miwa H, Matsumoto
- KMID: 2167272
- Gut Liver.
- 2011 Mar;5(1):37-45.
BACKGROUND/AIMS: Infliximab (IFX), an antibody to tumor necrosis factor, (TNF)-alpha has efficacy in treating Crohn's disease (CD). However, knowledge of the potential effects of IFX on patients' immune profiles is... -
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- Phase 2 single-arm study on the safety of maintenance niraparib in Japanese patients with platinum-sensitive relapsed ovarian cancer
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Takehara K, Matsumoto T, Hamanishi J, Hasegawa K, Matsuura M, Miura K, Nagao S, Nakai H, Tanaka N, Tokunaga H, Ushijima K, Watari H, Yokoyama Y, Kase Y, Sumino S, Suri A, Itamochi H, Takeshima N
- KMID: 2526362
- J Gynecol Oncol.
- 2021 Mar;32(2):e21.
- doi: 10.3802/jgo.2021.32.e21
Objective: The primary objective of this study was to evaluate the safety of niraparib 300 mg/day in Japanese patients with platinum-sensitive, relapsed ovarian cancer in a maintenance setting. Methods: Phase 2,... -
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- Phase 2 single-arm study on the efficacy and safety of niraparib in Japanese patients with heavily pretreated, homologous recombination-deficient ovarian cancer
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Okamoto A, Kondo E, Nakamura T, Yanagida S, Hamanishi J, Harano K, Hasegawa K, Hirasawa T, Hori K, Komiyama S, Matsuura M, Nakai H, Nakamura H, Sakata J, Tabata T, Takehara K, Takekuma M, Yokoyama Y, Kase Y, Sumino S, Soeda J, Suri A, Aoki D, Sugiyama T
- KMID: 2526354
- J Gynecol Oncol.
- 2021 Mar;32(2):e16.
- doi: 10.3802/jgo.2021.32.e16
Objective: To evaluate the efficacy and safety of niraparib in Japanese women with heavily pretreated ovarian cancer. Methods: This Phase 2 open-label, single-arm study enrolled Japanese women with homologous recombination deficiency-positive... -
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- Seven days triple therapy for eradication of Helicobacter pylori does not alter the disease activity of patients with inflammatory bowel disease
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Shinzaki S, Fujii T, Bamba S, Ogawa M, Kobayashi , Oshita M, Tanaka H, Ozeki K, Takahashi , Kitamoto H, Kani K, Nanjo S, Sugaya T, Sakakibara Y, Inokuchi T, Kakimoto K, Yamada A, Yasuhara H, Yokoyama Y, Yoshino T, Matsui A, Nakamura M, Tomizawa T, Sakemi R, Kamata N, Hibi T
- KMID: 2434163
- Intest Res.
- 2018 Oct;16(4):609-618.
- doi: 10.5217/ir.2018.00044
BACKGROUND/AIMS: The influences of Helicobacter pylori eradication therapy on the disease course of inflammatory bowel disease (IBD) are still unclear. We therefore conducted a multicenter, retrospective cohort study to evaluate... -
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