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Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway

Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W

BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found...
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The Influence of Bcl-3 Expression on Cell Migration and Chemosensitivity of Gastric Cancer Cells via Regulating Hypoxia-Induced Protective Autophagy

Hu L, Bai Z, Ma X, Bai N, Zhang Z

PURPOSE: Gastric cancer is a highly metastatic malignant tumor, often characterized by chemoresistance and high mortality. In the present study, we aimed to investigate the role of B-cell lymphoma 3...
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Diagnosis and treatment of interstitial lung disease: focusing on idiopathic pulmonary fibrosis

Kang HR, Choi SM

Interstitial lung disease (ILD) is a rare condition characterized by extensive inflammation and fibrosis mainly involving the pulmonary interstitium or alveoli. Usually, patients with ILD clinically present with chronic cough...
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Proteomic Classification and Identification of Proteins Related to Tissue Healing of Platelet-Rich Plasma

Lee HW, Choi KH, Kim JY, Kim KO, Haotian B, Yuxuan L, Noh KC

BACKGROUND: Platelet-rich plasma (PRP) is a plasma component of autologous blood containing a high concentration of platelets. PRP is used to promote healing of damaged tissues. However, there are not...
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Comparing intra-oral wound healing after alveoloplasty using silk sutures and n-butyl-2-cyanoacrylate

Suthar P, Shah S, Waknis P, Limaye G, Saha A, Sathe P

OBJECTIVES: The need for proper wound closure is of paramount importance after any intra-oral surgery. Various wound closure techniques have been described in literature using traditional non-absorbable suture materials. These...
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Cytocompatibility and cell proliferation evaluation of calcium phosphate-based root canal sealers

Mestieri L, Zaccara IM, Pinheiro L, Barletta F, Kopper PM, Grecca FS

OBJECTIVES: This study aimed to evaluate the cell viability and migration of Endosequence Bioceramic Root Canal Sealer (BC Sealer) compared to MTA Fillapex and AH Plus. MATERIALS AND METHODS: BC Sealer,...
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An improvement in acute wound healing in rats by the synergistic effect of photobiomodulation and arginine

Mostafavinia A, Bidram M, Avili AG, Mahmanzar , Karimifard SA, Sajadi E, Amini A, Hadipour Jahromy M, Ghoreishi , Chien S, Bayat M

In this probe, at first we examined the best route and dosage of arginine administration on wound healing in an excisional wound model in rats. Next, we intend to assess...
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Feasibility of Cultured Allogenic Keratinocyte Treatment for Third Degree Burns

Choi J, Cho JT, Choi JY, Seo BF, Jung SN

Allogenic keratinocyte application is widely used for treatment of second degree burns. However, there is no significant body of report on application of allogenic keratinocyte to third degree burns. A...
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Feasibility of TRPM8 Agonist Agent for Management of Skin Graft Donor Site

Choi J, Jung ER, Cho JT, Seo BF, Choi JY, Kwon H, Jung SN

PURPOSE: Wound healing and scar management of donor site after skin graft should not be overlooked. Patients continue to complain of dryness, itching sensation. Such discomfort can cause irritation to...
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Comparison of Limberg Flap and Karydakis Flap Surgery for the Treatment of Patients With Pilonidal Sinus Disease: A Single-Blinded Parallel Randomized Study

Alvandipour M, Zamani MS, Ghorbani M, Charati JY, Karami MY

PURPOSE: Pilonidal sinus disease is a common condition, which mostly affects young men. While various surgical techniques have been introduced for treating intergluteal pilonidal disease (IPD), controversies still exist regarding...
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Importance of various skin sutures in cheiloplasty of cleft lip

Kim SM

Last week, after our receiving online journal regarding Journal of the Korean Association of Oral and Maxillofacial Surgeons, we found a recently published original article by Alawode et al., entitled...
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Socket preservation using eggshell-derived nanohydroxyapatite with platelet-rich fibrin as a barrier membrane: a new technique

Kattimani , Lingamaneni KP, Kreedapathi GE, Kattappagari KK

OBJECTIVES: Socket grafting is vital to prevent bone resorption after tooth extraction. Several techniques to prevent resorption have been described, and various bone graft substitutes have been developed and used...
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Chemical Regeneration of Wound Defects: Relevance to the Canine Palatal Mucosa and Cell Cycle Up-Regulation in Human Gingival Fibroblasts

Lee K, Ben Amara , Lee SC, Leesungbok R, Chung MA, Koo KT, Lee SW

BACKGROUND: Trichloroacetic acid (TCA) is an agent widely applied in dermatology for skin regeneration. To test whether TCA can offer an advantage for the regeneration of oral soft tissue defects,...
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An Important Role of Macrophages for Wound Margin Regeneration in a Murine Flap Model

Won HR, Seo C, Lee HY, Roh J, Kim CH, Jang JY, Shin YS

BACKGROUND: Macrophages have been known to have diverse roles either after tissue damage or during the wound healing process; however, their roles in flap wound healing are poorly understood. In...
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Bladder Augmentation Using Lyoplant® : First Experimental Results in Rats

Winde F, Backhaus K, Zeitler JA, Schlegel N, Meyer T

BACKGROUND: Congenital defects of the urinary bladder (micro- or contracted bladder, bladder exstrophy) remain a challenging problem for pediatric surgeons. Even when conservative treatment options are fully exhausted, irreversible renal...
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Wound Healing Potential of Low Temperature Plasma in Human Primary Epidermal Keratinocytes

Cui HS, Cho YS, Joo SY, Mun CH, Seo CH, Kim JB

BACKGROUND: Low temperature plasma (LTP) was recently shown to be potentially useful for biomedical applications such as bleeding cessation, cancer treatment, and wound healing, among others. Keratinocytes are a major...
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Platelet-rich fibrin along with a modified minimally invasive surgical technique for the treatment of intrabony defects: a randomized clinical trial

Ahmad N, Tewari S, Narula SC, Sharma RK, Tanwar N

PURPOSE: The modified minimally invasive surgical technique (M-MIST) has been successfully employed to achieve periodontal regeneration. Platelet-rich fibrin (PRF) is known to enhance wound healing through the release of growth...
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Radiation Induced Perineo-Coccygeal Defect Coverage with Latissimus Dorsi Musculocutaneous Free Flap

Oh J, Jeon JI, Eun S

Perineal defect reconstruction is usually encountered in oncological conditions, trauma, or infection such as Fournier's gangrene. Reconstructive surgeons face challenges due to the complex structure and diversity of the different...
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Fluid management in perioperative and critically ill patients

Kang D, Yoo KY

Fluid therapy to restore and/or maintain tissue perfusion may affect patient outcomes in perioperative, emergency, and intensive care. Kinetic analyses and outcome-oriented studies have provided more insight into fluid management....
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Preparation of harvested skin using the Versajet Hydrosurgery System in full-thickness skin grafts

Choi SG, Shin HW, Yoon KC

During a full-thickness skin graft procedure, the thickness of the harvested donor skin is adjusted based on the location of the recipient site and the judgment of the surgeon. Conventionally,...
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