- Effects of Uridine 5'-Triphosphate on the Vascular Tone of Rat Thoracic Aorta
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Park KS, Kong ID, Lee JW
- KMID: 2228958
- Korean Circ J.
- 1995 Feb;25(1):68-77.
- doi: 10.4070/kcj.1995.25.1.68
BACKGROUND: Uracil nucleotides are stored in platelets and all other cells, and are released into the extracellular space upon stimulation. They show various biological responses but their actions and mechanism... -
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- Effect of Uridine 5'-Triphosphate on Mucin Secretion in Human Middle Ear Epithelial Cells
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Choi JY, Lim JT, Yoon JH
- KMID: 2275992
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Feb;46(2):100-104.
BACKGROUND AND OBJECTIVES: Extracellular uridine 5'-triphosphate (UTP) regulates a variety of biological functions in the airway epithelium including chloride and fluid transport, mucociliary clearance, and mucin secretion via P2Y purinergic... -
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- The Protective Effect of Mannitol and Methylprednisolone in the Acute Focal Cerebral Ischemia in Cats
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Shin KM
- KMID: 2170822
- Ewha Med J.
- 1988 Dec;11(4):283-297.
- doi: 10.12771/emj.1988.11.4.283
It is the purpose of the this experimental study to investigate the protective effect of pretreatment of mannitol and methylprednisolone(MP) on the changes of the high-energy metabolites(nucleotides ; derivatives of... -
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- An Experimental Study of the Biochemical Alterations in the Acute Focal Cerebral Ischemia:Disturbance of Energy Metabolism
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Sheen YC, Shin KM
- KMID: 2187657
- J Korean Neurosurg Soc.
- 1989 Apr;18(4):525-533.
The energy metabolism of the brain has been measured in cat model using high performance liquid chromatography(HPLC). The experimental groups were divided into three according to the duration of ischemia.... -
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- Effect of Caffeine on UTP-induced Ca2+ Mobilization and Mucin Secretion in Human Middle Ear Epithelial Cells
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Choi JY, Kim SH, Jung SH, Son EJ, Park HY, Shin JW, Yoon JH
- KMID: 2276596
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Mar;49(3):263-268.
BACKGROUND AND OBJECTIVES: Puringeric receptors and their agonists like uridine-5-triphosphate (UTP) and adenosine triphosphate (ATP), regulate mucin secretion in middle ear epithelial cells. In the present study, we examined the... -
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- The Combined Therapeutic Effect of Drugs in Experimental Acute Focal Cerebral Ischemia
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Yoo DJ, Shin KM, Han JS
- KMID: 1673474
- J Korean Neurosurg Soc.
- 1990 Feb;19(2):217-224.
The study was designed to examine the effects of pretreatment with mannitol, methyl prednisolone and nimodipine on the acute focal cerebral ischemia in the cats of occlusion of the proximal... -
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- Asymmetrical distribution of P2Y nucleotide receptors in rabbit inner medullary collecting duct cells
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Woo JS, Jung JS, Kim YK
- KMID: 1917024
- Korean J Physiol Pharmacol.
- 2000 Aug;4(4):311-318.
We cultured the rabbit inner medullary collecting duct (IMCD) cells as monolayers on collagen-coated membrane filters, and investigated distribution of the P2Y receptors by analyzing nucleotide-induced short circuit current (Isc) responses. Exposure to... -
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- Uridine-5'-Triphosphate Stimulates Chloride Secretion via Cystic Fibrosis Transmembrane Conductance Regulator and Ca2+-Activated Chloride Channels in Cultured Human Middle Ear Epithelial Cells
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Son EJ, Gee HY, Lee MG, Lee WS, Choi JY
- KMID: 2277285
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2011 Dec;54(12):840-846.
- doi: 10.3342/kjorl-hns.2011.54.12.840
BACKGROUND AND OBJECTIVES: Nucleotide binding to purinergic P2Y receptors contributes to the regulation of fluid and ion transport in the middle ear epithelial cells. Here, we investigated the regulatory mechanism... -
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- Experimental Study of the Protection Against the Acute Focal Cerebral Ischemia
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Shim KM
- KMID: 2170834
- Ewha Med J.
- 1989 Mar;12(1):33-44.
- doi: 10.12771/emj.1989.12.1.33
The purpose of this experimental study is to determine the protective effect of pretreatment of mannitol, methylprednisolone, thiopental sodium and nimodipine against the acute focal cerebral ischemia. The energy metabolisms... -
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- Evidence for adenosine triphosphate (ATP) as an excitatory neurotransmitter in guinea-pig gastric antrum
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Kang TM, Xu W, Kim SJ, Ahn SC, Kim YC, So I, Park MK, Uhm DY, Kim KW
- KMID: 1554134
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):165-174.
We explore the question of whether adenosine 5'-triphosphate (ATP) acts as an excitatory neurotransmitter in guinea-pig gastric smooth muscle. In an organ bath system, isometric force of the circular smooth muscle of guinea-pig... -
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- Hemodynamic characteristics of extracellular UTP in the perfused rat liver
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Kong ID, Chung HS, Park KS, Han JK, Lee JW
- KMID: 2158055
- Yonsei Med J.
- 1996 Aug;37(4):262-269.
- doi: 10.3349/ymj.1996.37.4.262
Uridine 5'-triphosphate (UTP) is stored in the granules of cells such as platelets and is released into the extracellular space upon cell stimulation. Extracellular UTP is known to influence many... -
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- Vascular Reactivity by Purinoceptor Activation in Rat Inferior Vena Cava
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Lee BS, Chung HS, Park KS, Kong ID, Jeong SW, Lee JW
- KMID: 2093759
- Korean Circ J.
- 2000 Sep;30(9):1156-1164.
- doi: 10.4070/kcj.2000.30.9.1156
BACKGROUND: Extracellular ATP, released from platelets and nerve endings, plays significant roles in the regulation of circulation. The effects of ATP depend on the location of the vessels and the... -
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- In vitro Transcription of Prospect Hill virus S Genome Segment Produced by RT-PCR
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Lee PW, Park MS
- KMID: 2146936
- J Korean Soc Microbiol.
- 1998 Feb;33(1):39-48.
Prospect Hill virus (PHV) is related antigenically but distinct to Hantaan virus. As a member of genus Hantavirus, PHV has three segmented RNA genome. Among these segments, Small segment(S) encodes... -
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- Membrane-Specific Expression of Functional Purinergic Receptors in Normal Human Nasal Epithelial Cells
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Kim CH, Kim SS, Yoo JB, Lee SY, Song MH, Lee JG, Yoon JH
- KMID: 1597341
- Korean J Otolaryngol-Head Neck Surg.
- 2005 May;48(5):606-614.
BACKGROUND AND OBJECTIVES: Extracellular purines and pyrimidines regulate various physiological responses via cell surface receptors known as purinoreceptors, and may exert autocrine or paracrine effects on ion transport, fluid transport,... -
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- The Role of ATP on Reactive Oxygen Species Generation and Cellular Proliferation in BV-2 Cells
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Kim YH, Cho JK, Huh PW, Lim Y, Rha HK, Whang KT
- KMID: 2007391
- J Korean Child Neurol Soc.
- 2003 Nov;11(2):238-248.
PURPOSE: Adenosine triphosphate (ATP) evokes several cellular responses in microglia including propagation. However, the role of the purinoceptor on ROS generation in microglia is unclear. In order to determine the... -
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- Treatment with MnTBAP Protects Against Early Nuclear Translocation of Endonuclease G and Reduces Cerebral Infarction after Focal Cerebral Ischemia/Reperfusion in Mice
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Kim HW, Cho KJ, Kim HJ, Cho YJ, Lee BI, Kim GW
- KMID: 2343293
- J Korean Neurol Assoc.
- 2007 Nov;25(4):535-543.
BACKGROUND: Reactive Oxygen Species (ROS) have been implicated in the pathophysiology of brain injury after ischemia/reperfusion. Recently, it has been reported that endonuclease G (EndoG), a mitochondrial protein, is activated... -
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- The Relationship between the Histological Findings and beta ig-h3 in IgA Nephropathy
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Choi HJ, Choi JY, Park JY, Lee HC, Jang MH, Kim JC, Kim CD, Kim YL, Lee EG, Kim IS, Kim YJ, Park MO, Park SH
- KMID: 2254888
- Korean J Nephrol.
- 2004 Nov;23(6):898-906.
BACKGROUND: TGF-beta is involved in the pathogenesis of various kidney diseases characterized by glomerulosclerosis and tubulointerstitial fibrosis. It is reported that urinary TGF-beta reflects the grade of interstitial fibrosis in... -
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