- Genetic and Epigenetic Marker-Based DNA Test of Stool Is a Promising Approach for Colorectal Cancer Screening
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An SW, Kim NK, Chung HC
- KMID: 1758558
- Yonsei Med J.
- 2009 Jun;50(3):331-334.
- doi: 10.3349/ymj.2009.50.3.331
Colorectal cancer (CRC) is one of the most common malignancies and leading cause of cancer-related deaths in the world. However, it may be treated effectively by surgical removal of the... -
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- Clinical Significance of Aberrant Wnt7a Promoter Methylation in Human Non-Small Cell Lung Cancer in Koreans
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Kim TH, Moon JY, Kim SH, Paik SS, Yoon HJ, Shin DH, Park SS, Sohn JW
- KMID: 2129645
- J Korean Med Sci.
- 2015 Feb;30(2):155-161.
- doi: 10.3346/jkms.2015.30.2.155
The Wnt signaling pathway has regulatory roles in cell proliferation, differentiation, and polarity. Aberrant Wnt pathway regulation can lead to abnormal cell proliferation and cancer, and loss of Wnt7a expression... -
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- Candidates for Tumor Markers of Cervical Cancer Discovered by Proteomic Analysis
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Song JY, Bae HS, Koo DH, Lee JK, Jung HH, Lee KW, Lee NW
- KMID: 2157970
- J Korean Med Sci.
- 2012 Dec;27(12):1479-1485.
- doi: 10.3346/jkms.2012.27.12.1479
Cervical cancer is the second most common gynecological cancer among Korean women. While nationwide screening program has developed, the pathogenesis of cervical cancer is unknown. The aim of this study... -
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- Clinicopathologic Significance of Gastric and Intestinal Phenotypic Marker Expression in Gastric Carcinomas
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Kim GH, Song GA, Park DY, Lee DH, Kim TO, Lee SH, Heo J, Kang DH, Cho M
- KMID: 1782229
- Korean J Intern Med.
- 2005 Sep;20(3):191-197.
- doi: 10.3904/kjim.2005.20.3.191
BACKGROUND: It is well known that both gastric and intestinal phenotypic cell markers are expressed in gastric cancers. This study was aimed at investigating the correlation between gastric and intestinal... -
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- Impact of Interleukin-10 Gene Polymorphisms on Survival in Patients with Colorectal Cancer
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Ting WC, Chen LM, Huang LC, Hour MJ, Lan YH, Lee HZ, You BJ, Chang TY, Bao BY
- KMID: 1793044
- J Korean Med Sci.
- 2013 Sep;28(9):1302-1306.
- doi: 10.3346/jkms.2013.28.9.1302
Chronic inflammation is thought to be the leading cause of colorectal cancer, and interleukin-10 (IL10) has been identified as a potent immunomodulatory cytokine that regulates inflammatory responses in the gastrointestinal... -
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- Intravenous KITENIN shRNA Injection Suppresses Hepatic Metastasis and Recurrence of Colon Cancer in an Orthotopic Mouse Model
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Hwang JE, Shim HJ, Park YK, Cho SH, Bae WK, Kim DE, Kim KK, Chung IJ
- KMID: 1123443
- J Korean Med Sci.
- 2011 Nov;26(11):1439-1445.
- doi: 10.3346/jkms.2011.26.11.1439
KITENIN (KAI1 C-terminal interacting tetraspanin) promotes invasion and metastasis in mouse colon cancer models. In the present study, we evaluated the effects of KITENIN knockdown by intravenous administration of short... -
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- Prognostic Significance of p21 and p53 Expression in Gastric Cancer
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Seo YH, Joo YE, Choi SK, Rew JS, Park CS, Kim SJ
- KMID: 1106143
- Korean J Intern Med.
- 2003 Jun;18(2):98-103.
BACKGROUND: Cyclin-dependent kinase inhibitors (CDKI), including p21, p27 and p57 of the KIP family, are negative regulators of cell cycle progression and potentially act as tumor suppressors. The expression of... -
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- High Frequency of Genetic Alterations in Non-small Cell Lung Cancer Detected by Multi-target Fluorescence In Situ Hybridization
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Kang JU, Koo SH, Kwon KC, Park JW, Shin SY, Kim JM, Jung SS
- KMID: 1785788
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S47-S51.
- doi: 10.3346/jkms.2007.22.S.S47
Detection of genetic alterations could provide a tool as an adjuvant for the diagnosis of non-small cell lung cancer (NSCLC) and to define patients at risk for early relapse. In... -
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- Analysis of Gene Expression in Primary Hepatocellular Carcinoma Using Differentially Displayed Reverse Transcriptase Polymerase Chain Reaction
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Lee YC, Hur W, Choi JE, Piao LS, Hong SW, Bae SH, Choi JY, Yoon SK
- KMID: 1792753
- Korean J Gastroenterol.
- 2009 Jun;53(6):361-368.
- doi: 10.4166/kjg.2009.53.6.361
BACKGROUND/AIMS: The investigation of a specific tumor marker for hepatocellular carcinoma (HCC) is needed to examine the carcinogenesis and to select the patients for treatment options. The aim of this... -
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- Prognostic Significance of HER2 Gene Amplification According to Stage of Breast Cancer
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Kim YS, Won YS, Park KS, Song BJ, Kim JS, Oh SJ, Jeon HM, Jung SS, Park WC
- KMID: 1786878
- J Korean Med Sci.
- 2008 Jun;23(3):414-420.
- doi: 10.3346/jkms.2008.23.3.414
It is well known that the amplification of the HER2 gene is closely associated with poor prognosis of breast cancer. However, there is controversy about the clinical significance of HER2... -
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- Gene Expression Profiling using Oligonucleotide Microarray in Atrophic Gastritis and Intestinal Metaplasia
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Kim KR, Oh SY, Park UC, Wang JH, Lee JD, Kweon HJ, Kim SY, Park SH, Choi DK, Kim CG, Choi SH
- KMID: 1112539
- Korean J Gastroenterol.
- 2007 Apr;49(4):209-224.
BACKGROUND/AIMS: The atrophic gastritis with intestinal metaplasia of gastric mucosa has been considered to be the major factor of carcinogenesis in the stomach. However, the key molecules are still poorly... -
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