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Blood Management Protocol without Transfusion in Orthopedic Surgery

Suh YS, Lee JJ, Nho JH, Chung H, Lee WS, Jang BW, Kim YB, Chun DI, Choi SW, Lee JC, Choi HS

We developed a new blood management protocol that allows patients to not undergo transfusion during major orthopaedic surgery. Here, we report the safety of or our protocol. The preoperative pharmacological...
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Effect of intravenous tranexamic acid on perioperative bleeding and transfusion in spine surgery: systematic review and meta-analysis of randomized controlled trials

Lee D, Choi SJ, Lee WY, Kim KM, Kim MC, Lee S

BACKGROUND: This study aimed to systematically review the literature investigating the effect of intravenous (IV) tranexamic acid (TXA) on the perioperative blood loss and amount of transfused blood in patients...
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Role of Suction Drain after Knee Arthroplasty in the Tranexamic Acid Era: A Randomized Controlled Study

Maniar RN, Pradhan P, Bhatnagar , Maniar A, Bidwai R, Bindal P

BACKGROUND: Postoperative suction drains are used after total knee arthroplasty to avoid intra-articular hematoma formation although they can increase blood loss due to a negative suction effect. The use of...
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A Randomized Controlled Trial of Topical Application of Tranexamic Acid in Patients with Thoracolumbar Spine Trauma Undergoing Long-Segment Instrumented Posterior Spinal Fusion

Sudprasert W, Tanaviriyachai T, Choovongkomol K, Jongkittanakul S, Piyapromdee U

STUDY DESIGN: Prospective, randomized controlled trial. PURPOSE: To evaluate the effect of topically applied tranexamic acid (TXA) on postoperative blood loss of neurologically intact patients with thoracolumbar spine trauma. OVERVIEW OF LITERATURE:...
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When do we need more than local compression to control intraoral haemorrhage?

Sohn JB, Lee H, Han YS, Jung DU, Sim HY, Kim HS, Oh S

OBJECTIVES: The aims of this study were to determine the effectiveness of local compression in patients presenting to the emergency room with intraoral bleeding and to identify when complex haemostatic...
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Coagulation abnormalities and bleeding in pregnancy: an anesthesiologist's perspective

Yoon HJ

During pregnancy, the procoagulant activity increases (manifested by elevation in factor VII, factor VIII, factor X, and fibrinogen levels), while the anticoagulant activity decreases (characterized by reduction in fibrinolysis and...
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Predictors of Hematoma Enlargement in Patients with Spontaneous Intracerebral Hemorrhage Treated with Rapid Administration of Antifibrinolytic Agents and Strict Conservative Management

Kim CH, Lee SW, Kim YH, Sung SK, Son DW, Song GS

OBJECTIVE: Spontaneous intracerebral hemorrhage (ICH) is caused by the rupture of small blood vessels and other health problems. In ICH patients, hematoma enlargement is the most critical risk factor for...
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Minimal Dose of Tranexamic Acid Is Effective in Reducing Blood Loss in Complex Spine Surgeries: A Randomized Double-Blind Placebo Controlled Study

Shakeri M, Salehpour , Shokouhi G, Aeinfar K, Aghazadeh , Mirzaei F, Alavi SA

STUDY DESIGN: A randomized double-blind placebo controlled study. PURPOSE: In the present study, we aimed to assess the efficacy of tranexamic acid (TXA) in reducing blood loss after laminectomy and posterolateral...
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Is irrational use of tranexamic acid justified in anesthesia practice?

Gupta B

No abstract available.
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Comparison of Blood Loss between Intra-Articular and Intravenous Tranexamic Acid Following Primary Total Knee Arthroplasty

Lee GC, Kim DH, Lee JW, Kang SW, Cho SW

PURPOSE: To investigate the difference in blood loss between two injection methods, intravenous (IV) and intra-articular (IA) methods via drain tube. MATERIALS AND METHODS: A total of 183 patients who underwent...
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A Paradigm Shift: Perioperative Iron and Erythropoietin Therapy for Patient Blood Management

Lee H, Yuh YJ

Allogeneic blood transfusion is often restricted due to its adverse effects, a lack of blood supply, and religious or cultural constraints. As a result, patient blood management (PBM) has been...
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Liver lesions detected in a hepatitis B core total antibody-positive patient masquerading as hepatocellular carcinoma: a rare case of peliosis hepatis and a review of the literature

Tan CH, Soon GS, Kow WC

Peliosis Hepatis (PH) is a rare vascular disorder of the liver, characterized by the presence of cystic blood-filled cavities distributed throughout the hepatic parenchyma. The pathogenesis of PH remains controversial....
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Management of Blood Loss in Hip Arthroplasty: Korean Hip Society Current Consensus

Song JH, Park JW, Lee YK, Kim IS, Nho JH, Lee KJ, Park KK, Kim Y, Park JH, Han SB

The volume of hip arthroplasty is stiffly increasing because of excellent clinical outcomes, however it has not been shown to decrease the incidence of transfusions due to bleeding related to...
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Efficacy of Topical Tranexamic Acid in Treatment of Melasma

Yoo J, Ahn H, Kim MS, Jue MS, Choi KH

  • KMID: 2386238
  • Korean J Dermatol.
  • 2017 Jun;55(5):283-289.
BACKGROUND: Tranexamic acid (TXA), a plasmin inhibitor, has been used orally or via intradermal injection to treat melasma; however, there are limited studies regarding efficacy and safety of topical application...
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The antiplaque and bleeding control effects of a cetylpyridinium chloride and tranexamic acid mouth rinse in patients with gingivitis

Lee JE, Lee JM, Lee Y, Park JW, Suh JY, Um HS, Kim YG

PURPOSE: This study aimed to evaluate the effects of a cetylpyridinium chloride (CPC) and tranexamic acid (TXA) mouth rinse on patients with gingivitis. METHODS: This randomized, placebo-controlled, double-blind, parallel-group, clinical trial...
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Blood Sparing Efficacy of Oral Tranexamic Acid in Primary Total Knee Arthroplasty: A Randomized Controlled Trial

Lee QJ, Ching WY, Wong YC

PURPOSE: Tranexamic acid (TXA) is effective in reducing blood loss in primary total knee replacement. Almost all studies used an intravenous form or a topical form. The aim of this...
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What Are the Optimal Dose of Administration and Time of Drainage for Topical Tranexamic Acid in Patients Undergoing Cardiac Surgery?

Nouraei SM

No abstract available.
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Tranexamic Acid-Induced Acute Renal Cortical Necrosis in Post-Endoscopic Papillectomy Bleeding

Ko DH, Kim TH, Kim JW, Gu JJ, Yoon BH, Oh JH, Hong SG

Acute renal failure can be the result of acute renal cortical necrosis (RCN), which commonly occurs from complications occurring during pregnancy. RCN is rarely caused by medications, although tranexamic acid,...
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Treatment Effect of Tranexamic Acid in Plasma D-dimer Level Elevated Anti-histamine Resistant Chronic Urticaria Patients

Jun JY, Park JH, Lee JH, Lee DY, Lee JH, Yang JM

  • KMID: 2396853
  • Korean J Dermatol.
  • 2017 Nov;55(9):628-629.
No abstract available.
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Effectiveness and Safety of Tranexamic Acid in Spinal Deformity Surgery

Choi HY, Hyun SJ, Kim KJ, Jahng TA, Kim HJ

OBJECTIVE: Spinal deformity surgery has the potential risk of massive blood loss. To reduce surgical bleeding, the use of tranexamic acid (TXA) became popular in spinal surgery, recently. The purpose...
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