- Upregulation of Macrophage Migration Inhibitory Factor (MIF) Production by Engagement of Toll-like Receptor 3 (TLR3) on Fibroblast-like Synoviocyte (FLS) from Patients with Rheumatoid Arthritis
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Her YM, Park SH, Park MK, Oh HJ, Kang KY, Cho ML
- KMID: 2202128
- J Korean Rheum Assoc.
- 2009 Jun;16(2):123-132.
- doi: 10.4078/jkra.2009.16.2.123
OBJECTIVE: Rheumatoid arthritis (RA) is a chronic autoimmune disease. Macrophage migration inhibitory factor (MIF) has been shown to be an important pro-inflammatory cytokine in RA. The aim of this study... -
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- Role of Toll-like Receptor 3 Variants in Aspirin-Exacerbated Respiratory Disease
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Palikhe NS, Kim SH, Kim JH, Losol P, Ye YM, Park HS
- KMID: 2130364
- Allergy Asthma Immunol Res.
- 2011 Apr;3(2):123-127.
- doi: 10.4168/aair.2011.3.2.123
PURPOSE: Although the mechanism of virus-induced, aspirin-exacerbated respiratory disease (AERD) is not known fully, direct activation of viral components through Toll-like receptor 3 (TLR3) has been suggested. TLR3 recognizes double-stranded... -
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- Sex hormones alter the response of Toll-like receptor 3 to its specific ligand in fallopian tube epithelial cells
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Zandieh Z, Amjadi F, Vakilian H, Aflatoonian K, Amirchaghmaghi E, Fazeli A, Aflatoonian R
- KMID: 2427410
- Clin Exp Reprod Med.
- 2018 Dec;45(4):154-162.
- doi: 10.5653/cerm.2018.45.4.154
OBJECTIVE: The fallopian tubes play a critical role in the early events of fertilization. The rapid innate immune defense is an important part of the fallopian tubes. Toll-like receptor 3... -
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- Expression of Toll-Like Receptors in Verruca and Molluscum Contagiosum
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Ku JK, Kwon HJ, Kim MY, Kang H, Song PI, Armstrong , Ansel JC, Kim HO, Park YM
- KMID: 1713466
- J Korean Med Sci.
- 2008 Apr;23(2):307-314.
- doi: 10.3346/jkms.2008.23.2.307
Recent studies indicate that several Toll-like receptors (TLRs) are implicated in recognizing viral structures and instigating immune responses against viral infections. The aim of this study is to examine the... -
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- Association of TLR3 gene polymorphism with IgG subclass deficiency and the severity in patients with aspirin-intolerant asthma
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Kim SH, Yang EM, Jung HM, Pham DL, Choi HN, Ban GY, Park HS
- KMID: 2346755
- Allergy Asthma Respir Dis.
- 2016 Jul;4(4):264-270.
- doi: 10.4168/aard.2016.4.4.264
PURPOSE: Toll-like receptor 3 (TLR3) recognizes to viral double-stranded RNA and is involved in antiviral defenses. A probable role of TLR3 gene variants in the pathogenesis of aspirin-intolerant asthma (AIA)... -
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- Ribosomal Protein L19 and L22 Modulate TLR3 Signaling
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Yang EJ, Seo JW, Choi IH
- KMID: 2150702
- Immune Netw.
- 2011 Jun;11(3):155-162.
- doi: 10.4110/in.2011.11.3.155
BACKGROUND: Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA) and induces inflammation. In this study we attempted to ascertain if there are endogenous host molecules controlling the production of cytokines... -
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- TRIM56 Suppresses Multiple Myeloma Progression by Activating TLR3/TRIF Signaling
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Chen Y, Zhao J, Li D, Hao J, He P, Wang H, Zhang M
- KMID: 2418847
- Yonsei Med J.
- 2018 Jan;59(1):43-50.
- doi: 10.3349/ymj.2018.59.1.43
PURPOSE: Tripartite-motif-containing protein 56 (TRIM56) has been found to exhibit a broad antiviral activity, depending upon E3 ligase activity. Here, we attempted to evaluate the function of TRIM56 in multiple... -
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- Engagement of Toll-Like Receptor 3 Induces Vascular Endothelial Growth Factor and Interleukin-8 in Human Rheumatoid Synovial Fibroblasts
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Moon SJ, Park MK, Oh HJ, Lee SY, Kwok SK, Cho ML, Ju JH, Park KS, Kim HY, Park SH
- KMID: 964725
- Korean J Intern Med.
- 2010 Dec;25(4):429-435.
- doi: 10.3904/kjim.2010.25.4.429
BACKGROUND/AIMS: Angiogenesis, which is a critical step in the initiation and progression of rheumatoid arthritis (RA), involves pro-angiogenic factors, including interleukin (IL)-8 and vascular endothelial growth factor (VEGF). We investigated... -
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- Studying the Effect of Downregulating Autophagy-Related Gene LC3 on TLR3 Apoptotic Pathway Mediated by dsRNA in Hepatocellular Carcinoma Cells
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Wang G, Zhang M, Li Y, Zhou J, Chen L
- KMID: 2367521
- Cancer Res Treat.
- 2017 Jan;49(1):230-245.
- doi: 10.4143/crt.2015.506
PURPOSE: The purpose of this study is to examine the role of the double-stranded RNA (dsRNA) activated Toll–interleukin-1 receptor domain-containing adaptor inducing interferon β (TRIF) signal pathway in triggering apoptosis... -
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