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Add-on Tiotropium in Chinese Patients With Moderate Asthma: A Pooled Subgroup Analysis of MezzoTinA-Asthma 1 and 2

Lin J, Wan H, Kang J, Ma Q, Chen P, Jin M, Wang H, Liu S, Hao Q, Lin Y, Su L, Hu N

PURPOSE: Asthma affects approximately 30 million patients in China; however, tiotropium data for Chinese patients is limited. This study aimed to assess the efficacy and safety of tiotropium in Chinese...
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Expression of Muscarinic Receptors and the Effect of Tiotropium Bromide in Aged Mouse Model of Chronic Asthma

Kang JY, Kim IK, Hur J, Kim SC, Lee SY, Kwon SS, Kim YK

BACKGROUND: Efficacy and safety of tiotropium bromide, a muscarinic receptor antagonist, in treatment of asthma have been reported. However, its effect on airway remodeling in chronic asthma of the elderly...
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Pharmacokinetic characteristics of fluticasone, salmeterol and tiotropium after concurrent inhalation

Sunwoo J, Rhee SJ, Lee S, Lee SW, Jung J, Son H, Jang IJ

Chronic obstructive pulmonary disease (COPD) is a type of progressive, obstructive lung disease characterized by long-term poor airflow. The symptoms of COPD may be relieved and its progression delayed by...
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The role of tiotropium in the management of asthma

Park HW

Asthma is a chronic respiratory disease characterized by reversible airway obstruction that is secondary to an allergic inflammation and excessive smooth muscle contraction. Cholinergic signals were known to contribute significantly...
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