- Role of Ultrastructural Alterations of Intercellular Junction and Tight-junction Proteins in Patients With Gastroesophageal Reflux Disease
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Kim JW
- KMID: 2325780
- J Neurogastroenterol Motil.
- 2013 Oct;19(4):547-548.
No abstract available. -
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- Relevance of Ultrastructural Alterations of Intercellular Junction Morphology in Inflamed Human Esophagus
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Liu CC, Lee JW, Liu TT, Yi CH, Chen CL
- KMID: 2326232
- J Neurogastroenterol Motil.
- 2013 Jul;19(3):324-331.
BACKGROUND/AIMS: Detailed characterization of the ultrastructural morphology of intercellular space in gastroesophageal reflux disease has not been fully studied. We aimed to investigate whether subtle alteration in intercellular space structure... -
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- Effect of Acute Stress on Immune Cell Counts and the Expression of Tight Junction Proteins in the Duodenal Mucosa of Rats
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Lee HS, Kim DK, Kim YB, Lee KJ
- KMID: 2135070
- Gut Liver.
- 2013 Mar;7(2):190-196.
BACKGROUND/AIMS: Duodenal immune alterations have been reported in a subset of patients with functional dyspepsia (FD). The aim of this study was to investigate the effect of acute stress on... -
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- Indol-3-Carbinol Regulated Tight Junction Permeability and Associated-Protein Level and Suppressed Cell Invasion in Human Colon Cancer Cell Line, HT-29
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Kim SO, Choi YH, Choe WK
- KMID: 2261191
- Korean J Nutr.
- 2008 Jan;41(1):13-21.
To determine whether indol-3-carbinol (I3C, C9H9NO), an autolysis product of a glucosinolate and a glucobrassicin in vegetables, regulated tight junction proteins (TJ) and suppressed cell invasion in colon cancer cells,this... -
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- A Prospective Study of Eosinophilic Esophagitis and the Expression of Tight Junction Proteins in Patients with Gastroesophageal Reflux Disease Symptoms
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Okimoto K, Arai M, Ishigami H, Saito K, Minemura S, Maruoka D, Matsumura , Nakagawa T, Katsuno T, Suzuki M, Nakatani Y, Yokosuka O
- KMID: 2404714
- Gut Liver.
- 2018 Jan;12(1):30-37.
- doi: 10.5009/gnl16600
BACKGROUND/AIMS: Eosinophilic esophagitis (EoE) is often erroneously diagnosed as gastroesophageal reflux disease (GERD). The aim of this study is to investigate the prevalence of EoE and the expression of tight... -
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- Comparison of Tight Junction Protein-Related Gene mRNA Expression Levels between Male and Female Gastroesophageal Reflux Disease Patients
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Kim JJ, Kim N, Park JH, Kim YS, Lee SM, Lee DH, Jung HC
- KMID: 2417307
- Gut Liver.
- 2018 Jul;12(4):411-419.
- doi: 10.5009/gnl17419
BACKGROUND/AIMS: Male predominance has been observed in the erosive reflux disease (ERD), but reverse finding in nonerosive reflux disease (NERD). This suggests sex-specific medicine approach is needed but its mechanism... -
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- Additive Effects of Rebamipide Plus Proton Pump Inhibitors on the Expression of Tight Junction Proteins in a Rat Model of Gastro-Esophageal Reflux Disease
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Gweon TG, Park JH, Kim BW, Choi YK, Kim JS, Park SM, Kim CW, Kim HG, Chung JW, Incheon and Western Kyonggi Gastrointestinal Study Group
- KMID: 2404716
- Gut Liver.
- 2018 Jan;12(1):46-50.
- doi: 10.5009/gnl17078
BACKGROUND/AIMS: The aim of this study was to investigate the effects of rebamipide on tight junction proteins in the esophageal mucosa in a rat model of gastroesophageal reflux disease (GERD). METHODS:... -
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- German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells
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Lee KE, Jee HM, Hong JY, Kim MN, Oh MS, Kim YS, Kim KW, Kim KE, Sohn MH
- KMID: 2426337
- Yonsei Med J.
- 2018 Dec;59(10):1222-1231.
- doi: 10.3349/ymj.2018.59.10.1222
PURPOSE: Cockroach exposure is a pivotal cause of asthma. Tight junctions are intercellular structures required for maintenance of the barrier function of the airway epithelium, which is impaired in this... -
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- Significance of the Decreased Expressions of Claudin-1 and ZO-1 Protein as Prognostic Factors in Breast Cancer
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Kim MJ, Cha SJ, Park SI, Park SJ, Chang IT, Kim BG, Choi YS, Lee TJ
- KMID: 2040612
- J Korean Surg Soc.
- 2007 Jun;72(6):453-459.
PURPOSE: Tight junction proteins are either over-expressed or suppressed in some cancers. These suppressions of claudin-1 and ZO-1 protein are known to have a significant relationship with the progression of... -
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- Occludin Expression in Brain Tumors and its Relevance to Peritumoral Edema and Survival
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Park MW, Kim CH, Cheong JH, Bak KH, Kim JM, Oh SJ
- KMID: 2166058
- Cancer Res Treat.
- 2006 Jun;38(3):139-143.
PURPOSE: Peritumoral brain edema (PTBE) is a serious causative factor that contributes the morbidity or mortality of brain tumors. The development of PTBE is influenced by many factors, including such... -
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- Chlorogenic Acid Decreases Retinal Vascular Hyperpermeability in Diabetic Rat Model
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Shin JY, Sohn J, Park KH
- KMID: 1786971
- J Korean Med Sci.
- 2013 Apr;28(4):608-613.
- doi: 10.3346/jkms.2013.28.4.608
To evaluate the effect of chlorogenic acid (CGA), a polyphenol abundant in coffee, on retinal vascular leakage in the rat model of diabetic retinopathy, Sprague-Dawley rats were divided into four... -
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- Glutathione Protects Brain Endothelial Cells from Hydrogen Peroxide-Induced Oxidative Stress by Increasing Nrf2 Expression
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Song J, Kang SM, Lee WT, Park KA, Lee KM, Lee JE
- KMID: 2009029
- Exp Neurobiol.
- 2014 Mar;23(1):93-103.
- doi: 10.5607/en.2014.23.1.93
Glutathione (GSH) protects cells against oxidative stress by playing an antioxidant role. Protecting brain endothelial cells under oxidative stress is key to treating cerebrovascular diseases and neurodegenerative diseases including Alzheimer's... -
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- Expression of claudin-1, claudin-4 and zonula occludens-1 in cervical intraepithelial neoplasia and invasive squamous cell carcinoma
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Lee SK, Rho HK, Park TY, Kang KH, Cho TI, Lee TJ
- KMID: 2077793
- Korean J Obstet Gynecol.
- 2007 Oct;50(10):1378-1385.
OBJECTIVE: Cell to cell and cell to extracellular matrix interaction are crucial in tumor development and progression. Tight junction proteins such as claudins and zonula occludens-1 (ZO-1) play an important... -
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- Fermented Pueraria Lobata extract ameliorates dextran sulfate sodium-induced colitis by reducing pro-inflammatory cytokines and recovering intestinal barrier function
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Choi S, Woo JK, Jang YS, Kang JH, Jang JE, Yi TH, Park SY, Kim SY, Yoon YS, Oh SH
- KMID: 2353590
- Lab Anim Res.
- 2016 Sep;32(3):151-159.
- doi: 10.5625/lar.2016.32.3.151
Inflammatory bowel disease is a chronic inflammatory disorder occurring in the gastrointestinal track. However, the efficacy of current therapeutic strategies has been limited and accompanied by side effects. In order... -
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- Berberine Prevents Intestinal Mucosal Barrier Damage During Early Phase of Sepsis in Rat through the Toll-Like Receptors Signaling Pathway
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Li GX, Wang XM, Jiang T, Gong JF, Niu LY, Li N
- KMID: 2071812
- Korean J Physiol Pharmacol.
- 2015 Jan;19(1):1-7.
- doi: 10.4196/kjpp.2015.19.1.1
Our previous study has shown berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway. In... -
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