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Should the therapeutic range be changed with new reagent for activated partial thromboplastin time?

Song KS

  • KMID: 2306168
  • Korean J Med.
  • 2000 Nov;59(5):489-490.
No abstract available.
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Study of the Effect of Thromboplastin Preparation ( Thrombokinase ) on the Blood Coagulation

Lee YJ, Yoon DM, Cho CH, Park BM

Coagulants have been used for a long time to promote the hemostasis during operation. We have carried out the study to see the effect of the thromboplastin preparation. Thrombokinase, on...
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Intracerebral Hemorrhage in Newborn Infants Secondary to Vitamin K Deficiency

Jung S, Kim SH, Kang SS

  • KMID: 1953098
  • J Korean Neurosurg Soc.
  • 1989 Jan;18(1):143-147.
Intracerebral hemorrhage secondary to vitamin K deficiency is presented in three newborn infants: 4 days, 28 days and 21 days of age respectively. After the administration of vitamin K(5-10 mg)...
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Hemophilic Arthropaty: A Case Report

Park BM, Chung IH, Sohn SW

Hemophilia is a sex-linked recessive hereditary bleeding disorder occurring only in the male and transmitted by the female. This disease is characterized by a bleeding tendency due to prolonged coagulation...
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Vitamin K-Deficient Hemorrhagic Disease in Infants with Acute Subdural Hematoma

Cho KY, Jung S, Oh MS

  • KMID: 1954493
  • J Korean Neurosurg Soc.
  • 1991 Nov;20(10-11):924-929.
We had experienced 2 cases of acute subdural hematoma due to vitaimin K(vit. K) deficiency. They were 44-and 42-day-old. After the adminstration of vit.K1, prolonged prothrombin time(PT) and activated partial...
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A Comparative Study on a Home-made Thromboplastin

Lee WS, Kim TY, Choi YS

  • KMID: 2305231
  • Korean J Hematol.
  • 1998 Aug;33(2):243-250.
BACKGROUND: Thromboplastin extracted from human brain has been replaced by other animal sources due to the risk of infection. However, there is a variation in sensitivity according to the animal...
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Measurement of PT, aPTT, and Fibrinogen by Automatic Coagulation Analyzer, ACL9000

Kim YA, Sun YK

  • KMID: 2325360
  • J Lab Med Qual Assur.
  • 2002 Dec;24(2):201-207.
BACKGROUND: Newly developed ACL9000 automatic coagulation analyzer was evaluated in measurement of prothrombin time(PT), activated partial thromboplastin time(aPTT) and fibrinogen. METHODS: We studied precision including withtin-run and between-day precision. Normal reference...
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A Case of Acquired Hemophilia A

Kim JH, Lee WI, Yoon HJ, Park SY, Suh JT, Lee HJ

  • KMID: 1820205
  • J Lab Med Qual Assur.
  • 2003 Jun;25(1):207-209.
Acquired hemophilia is a rare acquired bleeding disorder. It occurs most frequently in elderly patients and in patients with associated underlying diseases such as autoimmune disorders, rheumatoid arthritis, malignancies, and...
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Acquired Hemophilia in a Patient Presenting with Swollen Left Limb

Kiam GW

Acquired hemophilia is a rare, potentially life-threatening disease that usually remains under-recognized especially in a primary setting; thus, diagnosing this disease is very challenging. Given its prevalence in elderly patients,...
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Establishing Therapeutic Ranges of Activated Partial Thromboplastin Time for Heparin Therapy using Anti-Xa Activity

Kim HK, Song KS, Park Q

  • KMID: 2225926
  • Korean J Clin Pathol.
  • 2000 Apr;20(2):126-131.
BACKGROUND: The commonly recommended therapeutic range is an activated partial thromboplastin time(APTT) of 1.5 to 2.5 times the control value, which may be inappropriate for some reagents. The aim of...
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Effects of Antioxidative, DPPH Radical Scavenging Activity and Antithrombogenic by the Extract of Sancho ( Zanthoxylum Schinifolium)

Jang MJ, Woo MH, Kim YH, Jun DY, Rhee SJ

  • KMID: 2269843
  • Korean J Nutr.
  • 2005 Jun;38(5):386-394.
Effects of root, stem and leaf extract of sancho (Zanthoxylum schinifolium) on the inhibition of lipid peroxidation in the hepatic microsome of rat, DPPH radical scavenging activity and activated partial...
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Observations of Prothrombin Time and Activated Partial Thromboplastin Time According to Various Conditioned Specimen

Keum DG, Kim WS, Choi JW

  • KMID: 1907545
  • J Clin Pathol Qual Control.
  • 1997 Dec;19(2):297-301.
BACKGROUND: Prothrombin time (PT) and activated partial thromboplastin time (aPTT) are widely used for screening coagulation disorders in most clinical laboratories. PT and aPTT are not completely identified in significant...
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Antibiotic-Induced Acquired Factor V Inhibitor

Lim DH, Kim TO, Jeong Y, Kim WJ, Park SJ, Lee JH, Jang SS

  • KMID: 2269273
  • Korean J Med.
  • 2014 Jul;87(1):105-109.
Acquired factor V inhibitor is a rare condition with a variety of clinical manifestations that range from no bleeding symptoms to life-threatening hemorrhage or thromboembolic events. Treatment is determined by...
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Enoxaparin-associated Retroperitoneal Hematoma in Two Chronic Dialysis Patients

Lee YK, Yoon SJ, Lee HH, Huh WS, Kim YG, Kim DJ, Oh HY

  • KMID: 2254445
  • Korean J Nephrol.
  • 2002 May;21(3):487-493.
Low molecular weight heparin has greater advantages over unfractionated heparin. It is more bioavailable, and laboratory monitoring is not necessary. Compared with unfractionated heparin, low molecular weight heparin does not...
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A Case of Congenital Factor XIII Deficiency Diagnosed by Semiquantitative Method

Park JE, Yang SE, Chi HS

  • KMID: 2083448
  • Korean J Hematol.
  • 2002 May;37(2):164-167.
Factor XIII (fibrin stabilizing factor) has roles of stabilizing clot and cross-linking fibrin polymer, so the congenital factor XIII deficient patient has clot unstability and delayed bleeding episodes. We experienced...
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Significance of Lupus Anticoagulant in Children with Prolonged Prothrombin Time/activated Partial Thromboplastin Time

Jo JH, Son DW, Jeon IS

BACKGROUND: The prolongation of prothrombin time (PT)/activated partial thromboplastin time (aPTT) in vitro occurs from various causes and lupus anticoagulant (LA) is one of them. This study was performed to...
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Training-induced changes in clotting parameters of athletic horses

Piccione G, Bazzano M, Giannetto , Marafioti , Fazio F

The purpose of this study was to investigate the effects of training on prothrombin time, activated partial thromboplastin time, and fibrinogen (Fb) concentrations in horses to assess potential adaptive response...
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Effects of Prolonged Major Surgery and Massive Transfusion on the Coagulation and Fibrinolysis System

Lee HW, Lim HJ, Chang SH, Shin JS

The anesthesiologist is sometime presented with the problem of coagulation defects through the perioperative period. The possible causes of inappropriate hemostasis in this situation are numerous, and multiple mechanism may...
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Effect of storage conditions on prothrombin time, activated partial thromboplastin time and fibrinogen concentration on canine plasma samples

Piccione G, Casella S, Giannetto , Giudice E

The present study was to assess the effect of storage conditions on prothrombin time (PT), activated partial thromboplastin time (aPTT) and fibrinogen concentration in blood samples of healthy dogs. Thirty-five...
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A Case of Secondary Antiphospholipid Antibody Syndrome with Thyroid Cancer

Kang SH, Choi SJ, Lee YH, Ji JD, Song GG

Antiphospholipid antibody syndrome (APS) is defined as the presence of lupus anticoagulant antibody or anticardiolipin antibody with vascular thrombosis or pregnancy complications. APS can be associated with autoimmune disease or...
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