Korean J Hematol.
2002 May;37(2):164-167.
A Case of Congenital Factor XIII Deficiency Diagnosed by Semiquantitative Method
- Affiliations
-
- 1Department of Pediatrics, Dan Kook University College of Medicine, Chonan, Korea. pedpje@dankook.ac.kr
- 2Department of Clinical Pathology, University of Ulsan, College of Medicine and Asan Medical Center, Seoul, Korea.
Abstract
- Factor XIII (fibrin stabilizing factor) has roles of stabilizing clot and cross-linking fibrin polymer, so the congenital factor XIII deficient patient has clot unstability and delayed bleeding episodes. We experienced a case of 11 years old girl who had experienced delayed umbilical healing, several episodes of intraabdominal and intracranial hemorrhage. But her coagulation screening studies with prothrombin time, aPTT (activated partial thromboplastin time), bleeding time showed normal value at each episode. These findings suggested typical features of congenital factor XIII deficiency. We used semiquantitative method to diagnose Factor XIII deficiency and quantify Factor XIII. We has treated her successfully with prophylactic fresh frozen plasma through plasmapheresis from two donors.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Effect of Plasma Coagulation Factor XIII Deficiency on the Healing Following Trabeculectomy in Rabbits
- The Effect of Additional Factor XIII on Cross-linking in Fibrin Glue
- Mining of mortality-related findings in rare bleeding disorders: a retrospective study from two centers
- A case of congenital factor V deficiency
- A Case of Intractable Gastrointestinal Bleeding during Chemotherapy in Hereditary Coagulation Factor Deficiency
