- Pancreatitis Induced by 6-mercaptopurine and 6-thioguanine in Childhood Acute Lymphoblastic Leukemia
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Yoon JH, Baek JS, Kim EK, Kang HJ, Shin HY, Ahn HS
- KMID: 1485158
- Korean J Hematol.
- 2008 Mar;43(1):53-57.
- doi: 10.5045/kjh.2008.43.1.53
Although pancreatitis is known as a common complication during the treatment of acute lymphoblastic leukemia, acute pancreatitis that's induced by 6-mercaptopurine or 6-thioguanine is very uncommon. We experienced the case... -
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- Treatment of Acute Myelogenous Leukemia in Children: Remission Induction with Adriamycin and Cytosine Arabinoside, and Postremission Maintenance Chemotherapy with Adriamycin, Cytosine Arabinoside and 6-thioguanine
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Kim SK, Ahn HS, Hong CY
- KMID: 1682617
- J Korean Pediatr Soc.
- 1988 Jul;31(7):850-862.
No abstract available. -
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- A Case of Leukemia Cutis in Erythroleukemia
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Hong KT, Park YK
- KMID: 2231366
- Korean J Dermatol.
- 1988 Apr;26(2):264-268.
A 13 years old girl came to our department with complaints of multiple ulcerating and non-ulcerating nodules on her back and buttocks since 1 month prior to visit. Skin biopsy... -
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- 6-Thioguanine-Induced Hepatic Sinusoidal Obstruction Syndrome in a Leukemic Child with TPMT Heterozygote
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Kwon YJ, Yoon JH, Park JA, Bang JS, Park BK, Choi JI, Kong SY, Park HJ
- KMID: 2049280
- Clin Pediatr Hematol Oncol.
- 2012 Oct;19(2):109-113.
Hepatic sinusoidal obstruction syndrome (hSOS) can be developed as a common complication after hematopoietic stem cell transplantation (HSCT), and rarely after 6-thioguanine-based chemotherapy without HSCT. A four-year-old boy with heterozygotic... -
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- Evaluation of Stability of Thiopurine Metabolites Using a Validated LC-MS/MS Method
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Yoo IY, Lee K, Ji OJ, Woo HI, Lee SY
- KMID: 2403460
- Ann Lab Med.
- 2018 May;38(3):255-260.
- doi: 10.3343/alm.2018.38.3.255
Measurement of thiopurine metabolites is helpful to monitor adverse effects and assess compliance in patients on thiopurine treatment. The purpose of this study was to develop and validate an analytical... -
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- A Case of Acute Leukemia Remitted by Adding Cyclosporin-A Previously Failed with Induction Therapy
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Park SB, Choe BK, Kim HS, Kang CM
- KMID: 2335503
- J Korean Pediatr Soc.
- 2000 Jul;43(7):988-992.
Clinical chemotherapy refractoriness is characterized by resistance to multiple drugs. Multidrug resistance(MDR) is caused by over-reactivity of a unidirectional drug efflux pump, transmembrane glycoprotein(P-glycoprotein), which is encoded by the MDR1 gene. P-glycoprotein leads... -
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- Induction Chemotherapy with BH-AC, Idarubicin, and 6-Thioguanine in Childhood Acute Myelogenous Leukemia
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Han HJ, Kang HJ, Lee JA, Choi HS, Park HJ, Seong KW, Yoo ES, Shin HY, Ahn HS
- KMID: 2335317
- J Korean Pediatr Soc.
- 1998 Feb;41(2):209-215.
PURPOSE: We have undertaken this study to evaluate the effects of induction chemotherapy involving BH-AC, idarubicin, and 6-thioguanine (6-TG). METHODS: BH-AC 300mg/m2/day was administered intravenously over three hours for seven... -
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- Induction Chemotherapy with N(4)-behenoyl-1-beta-D-arabinofuranosylcytosine, Idarubicin and 6-Thioguanine in Childhood Acute Myelogenous Leukemia
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Jang PS, Yoo KH, Hong JY, Shin HY, Ahn HS
- KMID: 1979926
- Korean J Pediatr Hematol Oncol.
- 2000 Apr;7(1):72-81.
PURPOSE: Retrospective study was performed to evaluate the survivals, remission rate and complications of induction chemotherapy using N(4)-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC), idarubicin and 6-thioguanine (6-TG) in newly diagnosed childhood acute... -
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- A Case of Bronchiolitis Obliterans Organizing Pneumonia Developed after Treatment of Acute Myelogenous Leukemia (M2) with Chloroma and Retinopathy
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Lee BC, Kim HL, Shin KW, Hong SA, Choi BK, Kim HS, Lee HJ, Kim KS, Kwon KY
- KMID: 2278321
- Korean J Pediatr Hematol Oncol.
- 2004 Oct;11(2):247-252.
Chloroma, a tumor consisted of primitive myeloid cells and located in extramedullary tissues, usually develops during or preceding the course of systemic leukemia, particularly acute myelogenous leukemia (FAB M2) with... -
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- Thiopurine S-Methyltransferase Polymorphisms in Korean Dermatologic Patients
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Lee M, Seo J, Bang D, Kim DY
- KMID: 2388902
- Ann Dermatol.
- 2017 Oct;29(5):529-535.
- doi: 10.5021/ad.2017.29.5.529
BACKGROUND: Thiopurine S-methyltransferase (TPMT) is an important enzyme in the metabolism of thiopurines including azathioprine (AZA), 6-mercaptopurine, and 6-thioguanine. TPMT genotyping is widely used for screening of AZA-related toxicity during... -
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- 3-Dimensional Dosimetry of Small Field Photon Beam
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Jang J, Kwon SI
- KMID: 1436554
- Korean J Med Phys.
- 2012 Mar;23(1):54-61.
A polymer gel dosimeter was fabricated. A 3-dimensional dosimetry experiment was performed in the small field of the photon of the cyberknife. The dosimeter was installed in a head and... -
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- NUDT15 Variants Cause Hematopoietic Toxicity with Low 6-TGN Levels in Children with Acute Lymphoblastic Leukemia
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Yi ES, Choi YB, Choi R, Lee NH, Lee JW, Yoo KH, Sung KW, Lee SY, Koo HH
- KMID: 2417876
- Cancer Res Treat.
- 2018 Jul;50(3):872-882.
- doi: 10.4143/crt.2017.283
PURPOSE: We aimed to identify the impact of NUDT15 variants on thiopurine intolerance and 6-thioguanine nucleotide (6-TGN) levels in Korean children with acute lymphoblastic leukemia (ALL). MATERIALS AND METHODS: Genotyping of... -
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- The Effect of Cytosine Arabinoside and Daunorubicin(AD) Combination Chemotherapy in Acute Myelogeous Leukemia
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Moon CH, Kim SH, Park HR, Cho JH, Kwon HC, Kim JS, Kim HJ
- KMID: 2006878
- J Korean Cancer Assoc.
- 1998 Aug;30(4):842-852.
PURPOSE: Important advances in the treatment of acute myelogenous leukemia have been made with the introduction of cytosine arabinoside(ara-C) and anthracycline(daunorubicin) over the past 20 years. Currently, 50 to 85%... -
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- Effect of Cytosine Arabinoside and Daunorubicin (AD) Combination Chemotherapy in Acute Myelogenous Leukemia
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Kang YS, Jeong HS, Kim TS, Yun HS, Kim DJ, Yun JH, Lee SG, Ji HG, Ham GH, Lee JH, Shin DB
- KMID: 1531935
- J Korean Cancer Assoc.
- 1997 Feb;29(1):160-170.
PURPOSE: Important advances in the treatment of acute myelogenous leukemia have been made with the introduction of cytosine arabinoside (ara-C) and anthracyclines (daunorubicin) over the past 20 years. Currently, 60... -
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- Idarubicin Plus Behenoyl Cytarabine and 6-thioguanine Compares Favorably with Idarubicin Plus Cytarabine-based Regimen for Children with Previously Untreated Acute Myeloid Leukemia: 10-Year Retrospective, Multicenter Study in Korea
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Lee DH, Chung NG, Cho B, Kim HK, Kang HJ, Shin HY, Ahn HS, Yoo KH, Sung KW, Koo HH, Kook H, Hwang TJ, Im HJ, Seo JJ, Park HJ
- KMID: 1713825
- J Korean Med Sci.
- 2010 Jan;25(1):9-15.
- doi: 10.3346/jkms.2010.25.1.9
We investigated the outcome of idarubicin plus N4-behenoyl-1-beta-D-arabinofuranosyl cytosine (BHAC)-based chemotherapy (BHAC group, n=149) compared to idarubicin plus cytarabine-based chemotherapy (cytarabine group, n=191) for childhood acute myeloid leukemia (AML). Between... -
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- Estimate of Radiation Doses in MDCT Using Patient Weight
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Kwon SO, Dong KR, Kweon DC, Goo EH, Choi J, Chung WK
- KMID: 1460190
- Korean J Med Phys.
- 2010 Sep;21(3):246-252.
The purpose of this study provides measurements of radiation dose from MDCT of head, chest, abdomen and pelvic examinations. A series of dose quantities that are measured of patient weight... -
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