- Troglitazone Enhances the Apoptotic Response of DLD-1 Colon Cancer Cells to Photodynamic Therapy
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Park H, Ko SH, Lee JM, Park JH, Choi YH
- KMID: 2427170
- Yonsei Med J.
- 2016 Nov;57(6):1494-1499.
- doi: 10.3349/ymj.2016.57.6.1494
PURPOSE: The aim of this study was to investigate whether the peroxisomal proliferator-activated receptor gamma (PPARγ) ligand troglitazone in combination with photodynamic therapy (PDT) enhances the apoptotic response of DLD-1... -
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- Adiponectin and thiazolidinedione targets CRTC2 to regulate hepatic gluconeogenesis
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Yoon YS, Ryu D, Lee MW, Hong S, Koo SH
- KMID: 1119323
- Exp Mol Med.
- 2009 Aug;41(8):577-583.
- doi: 10.3858/emm.2009.41.8.063
During fasting periods, hepatic glucose production is enhanced by glucagon to provide fuels for other organs. This process is mediated via cAMP-dependent induction of the CREB regulated transcriptional coactivator (CRTC)... -
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- IL-10 Mediates Rosiglitazone-Induced Kidney Protection in Cisplatin Nephrotoxicity
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Kim MG, Yang HN, Kim HW, Jo SK, Cho WY, Kim HK
- KMID: 1792925
- J Korean Med Sci.
- 2010 Apr;25(4):557-563.
- doi: 10.3346/jkms.2010.25.4.557
Cisplatin, a major anti-neoplastic drug, is known to be nephrotoxic and inflammation-inducing. A peroxisome proliferator-activated receptor gamma agonist, regulating lipid metabolism, has known to have anti-inflammatory effect, but the protection... -
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- The Inhibition of Insulin-stimulated Proliferation of Vascular Smooth Muscle Cells by Rosiglitazone Is Mediated by the Akt-mTOR-P70S6K Pathway
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Park S, Lim S, Chang W, Song H, Lee S, Song BW, Kim HJ, Cha MJ, Choi E, Jang Y, Chung N, Cho SY, Hwang KC
- KMID: 1793194
- Yonsei Med J.
- 2008 Aug;49(4):592-600.
- doi: 10.3349/ymj.2008.49.4.592
PURPOSE: Thiazolidinediones (TZDs) are known to inhibit the proliferation of vascular smooth muscle cell (VSMC) by increasing the activity of p27(Kip1) and retinoblastoma protein (RB). However, the upstream signaling mechanisms... -
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- Cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice are increased after rosiglitazone treatment
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Yoo DY, Kim W, Kim DW, Nam SM, Jung HY, Kim JW, Lee CH, Choi JH, Won MH, Yoon YS, Hwang IK
- KMID: 1737607
- J Vet Sci.
- 2014 Mar;15(1):27-33.
- doi: 10.4142/jvs.2014.15.1.27
In this study, we determined how rosiglitazone (RSG) differentially affected hippocampal neurogenesis in mice fed a low-fat diet (LFD) or high-fat diet (HFD; 60% fat). LFD and HFD were given... -
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- The Effect of Rosiglitazone on the Cell Proliferation and the Expressions of p27 and Skp2 in Helicobacter pylori Infected Human Gastric Epithelial Cells
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Kim SS, Cho YS, Kim HK, Shin OR, Chae HS, Choi MG, Chung IS
- KMID: 1792772
- Korean J Gastroenterol.
- 2010 Apr;55(4):225-231.
- doi: 10.4166/kjg.2010.55.4.225
BACKGROUND/AIMS: Ligands for peroxisome proliferator-activated receptor gamma (PPAR gamma), a member of the ligand-activated nuclear receptor superfamily, exhibit anti-tumoral effects and are associated with de novo synthesis of proteins involved... -
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- Induction of PPAR Gamma mRNA and Protein Expression by Rosiglitazone in Chronic Cyclosporine Nephropathy in the Rat
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Ahn KO, Lim SW, Yang HJ, Li C, Sugawara A, Ito S, Choi BS, Kim YS, Kim J, Yang CW
- KMID: 1779536
- Yonsei Med J.
- 2007 Apr;48(2):308-316.
- doi: 10.3349/ymj.2007.48.2.308
PURPOSE: We recently reported that rosiglitazone (RGTZ), a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist, has a protective effect against cyclosporine (CsA)- induced renal injury. Here we report the effect of... -
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