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Proposal of Laboratory Test Panel Based on Patients' Chief Complaints in Emergency Department

Lee HC, Kim YK, Song JH, Song KE

BACKGROUND: A test panel is a group of tests that are simultaneously performed for diagnosis and follow-up of patients. Organ-specific or disease-specific test panels are currently available. Since the patient's...
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A Case of Pseudoisodicentric Chromosome 18q Detected at Prenatal Diagnosis

Cho SY, Lim G, Kim SY, Kim MJ, Lee KA, Choi JR, Lee HJ, Suh JT, Park TS, Jung E

Although trisomy 18 (Edwards' syndrome) or the terminal deletion syndromes of 18p and 18q have been occasionally detected, pseudoisodicentric chromosome 18 is a very rare constitutional chromosomal abnormality. We describe...
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Evaluation of a Multiplex PCR Kit Used for Detecting Y Chromosome Microdeletions

Park MY, Kang HM, Hwang SH, Park HJ, Park NC, Choi KU, Kim HH, Chang CL, Lee EY

BACKGROUND: In addition to Klinefelter's syndrome, microdeletion of Yq is the most common genetic cause of male infertility; 15% of azoospermic or 5-10% of oligozoospermic males have Yq deletions. We...
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Detection of Allergen Specific IgE by AdvanSure Allergy Screen Test

Oh EJ, Lee SA, Lim J, Park YJ, Han K, Kim Y

BACKGROUND: In vitro serum allergen-specific IgE tests have been routinely used in the clinical diagnosis of allergic diseases. We evaluated the clinical usefulness of a newly introduced multiple antigen screen...
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Analysis of Patients with Positive Acid-fast Bacilli Culture and Negative T-SPOT.TB Results

Han YM, Kim HS, Kim CH, Kang HJ, Lee KM

BACKGROUND: T-SPOT.TB is a sensitive test that detects interferon-gamma producing T-cells in tuberculosis patients following stimulation with tuberculosis-specific antigens. Our study was aimed to investigate the possible causes of false...
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Clinical Significance of Serum Procalcitonin in Patients with Community-acquired Lobar Pneumonia

Lee JY, Hwang SJ, Shim JW, Jung HL, Park MS, Woo HY, Shim JY

BACKGROUND: Community-acquired pneumonia (CAP) is a common respiratory disorder in children, which necessitates hospitalization. Bacterial pneumonia, especially lobar pneumonia and parapneumonic effusions, is associated with considerably severe clinical course and...
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A Case of Disseminated Penicillium marneffei Infection in a Liver Transplant Recipient

Seo JY, Ma YE, Lee JH, Lee ST, Ki CS, Lee NY

Penicillium marneffei is the only dimorphic fungus among Penicillium spp. that can cause a fatal infection in immunocompromised patients. P. marneffei is endemic in Southeast Asia and eastern China. P....
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Usefulness of a Chromogenic Selective Agar for the Identification of Bacillus cereus Isolated from Blood Cultures

Jeong ES, Shin JH, Shin MG, Suh SP, Ryang DW

BACKGROUND: The incidence of Bacillus cereus bacteremia is increasing, but the identification of Bacillus species remains difficult. Brilliance Bacillus cereus agar (BBC agar; Oxoid, UK) is a new CHROMagar medium...
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Novel Influenza A (H1N1) Infection in Immunocompromised Patients

Seo KY, Lee HC, Kim YK, Lee WK, Song KE

BACKGROUND: Since April 2009, novel influenza A (H1N1) infection is spreading throughout the world. This infection might be fatal for immunocompromised patients who are at a potentially high risk of...
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A Comparison Analysis on the Diagnosis of Helicobacter pylori Infection and the Detection of Clarithromycin Resistance according to Biopsy Sites

Cho AR, Lee MK

BACKGROUND: This study was performed to determine the biopsy sites that are suitable for the diagnosis of Helicobacter pylori infection and to assess the sensitivity of culture, histology, and dual-priming...
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Evaluation of MicroScan Synergies plus Positive Combo 3 Panels for Identification and Antimicrobial Susceptibility Testing of Staphylococcus aureus and Enterococcus Species

Jung H, Lee NY

BACKGROUND: Few studies have evaluated the performance of the recently introduced MicroScan Synergies plus Positive Combo 3 Panels (SIPC3) (Dade Behring Inc., USA). We evaluated the clinical efficacy of the...
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Species Distribution and Antifungal Susceptibilities of Yeast Clinical Isolates from Three Hospitals in Korea, 2001 to 2007

Lee MK, Yong D, Kim M, Kim MN, Lee K

BACKGROUND: We utilized results from the ARTEMIS DISK Global Antifungal Surveillance Program to evaluate the species distribution and fluconazole and voriconazole susceptibilities of yeast isolates from clinical specimens in South...
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Study on Interpretation of Quantitative Results of Prostate-specific Antigen Using Information Theory

Hwang SH, Oh HB, Pyo T, Lee HJ, Lee KJ

BACKGROUND: The prostate-specific antigen (PSA) is considered the most useful among tumor markers currently used. However, its quantitative results are interpreted only qualitatively for the diagnosis of prostate cancer. The...
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Determination of Urinary Iodine Concentration by Inductively Coupled Plasma-mass Spectrometry in Thyroid Cancer Patients on Low-iodine Diet

Lee JH, Ji OJ, Song MJ, Park HD, Kim HK, Kim SW, Chung JH, Lee SY

BACKGROUND: Thyroid cancer patients should be on low-iodine diet (LID) before radioactive iodine therapy (RAIT) to maximize the effect of RAIT. Urinary iodine excretion is the most accurate marker of...
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Comparison of HbA(1c) Analyzers: D-10, Variant II Turbo, Cobas Integra 800, and Afinion AS100

Lee JY, Hong KS, Cho SE

BACKGROUND: The purpose of this study was to evaluate the performance and agreement among HbA(1c) values measured using selected analyzers certified by the National Glycohemoglobin Standardization Program (NGSP) and standardized...
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Flow-Assisted Differential Diagnosis of Hemolytic Anemia with Spherocytosis: A Case Report

Won DI

In patients with hemolytic anemia associated with spherocytosis, differential diagnosis has to be made whether the hemolysis is immune-mediated or of non-immune origin. We report a case of hereditary spherocytosis...
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A Case of Central Nervous System Myelomatosis with Complex Chromosome Aberrations

Bang HI, Yoo JY, Kim KH, Park R, Shin JW, Choi TY, Lee SC, Park HS, Won JH

Involvement of the central nervous system is very uncommon in multiple myeloma, observed in approximately 1% of the multiple myeloma patients. We report a case of central nervous system myelomatosis...
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A Case of del(16)(q22) in a Patient with Acute Myeloid Leukemia with Complex Karyotype

Kim M, Lee JW, Lee JK, Hong YJ, Hong SI, Kang HJ, Cho EH, Chang YH

Inversion of chromosome 16 [inv(16)(p13.1q22)] and t(16;16)(p13.1;q22) are associated with acute myelomonocytic leukemia (AMML) with eosinophilia and a favorable prognosis. On the other hand, patients with del(16)(q22) usually present with...
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