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Cell Lineage, Self-Renewal, and Epithelial-to-Mesenchymal Transition during Secondary Neurulation

Kawachi T, Tadokoro R, Takahashi Y

Secondary neurulation (SN) is a critical process to form the neural tube in the posterior region of the body including the tail. SN is distinct from the anteriorly occurring primary...
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Outcome of intradiscal condoliase injection therapy for patients with recurrent lumbar disc herniation

Suzuki N, Eguchi Y, Hirai T, Takahashi T, Takahashi Y, Watanabe K, Banno T, Sakaki K, Maki S, Takano Y, Taniguchi Y, Aoki Y, Konishi T, Hiraizumi Y, Yamagata M, Hirakawa A, Ohtori S

Study Design: Retrospective cohort study. Purpose: This study aimed to compare data from patients who received intradiscal condoliase (chondroitin sulfate ABC endolyase) injection for primary lumbar disc herniation (LDH) and recurrent...
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Interventional management for postoperative arterial bleeding in gastrointestinal surgery

Sato Y, Matsueda K, Osawa M, Inaba Y, Takahashi Y, Inoue Y, Oba A, Fukunaga Y, Shimizu Y

Postoperative arterial bleeding after gastrointestinal surgery is a potentially fatal complication. Transcatheter arterial embolization is considered the first-line treatment because of efficacy and less invasiveness despite the risk of organ...
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Clinical meaning of sarcopenia in patients undergoing endoscopic treatment

Hisada H, Tsuji Y, Kuribara H, Miyata R, Oshio K, Mizutani S, Nakagawa H, Cho R, Sakuma N, Miura Y, Mizutani H, Ohki D, Yakabi S, Takahashi Y, Sakaguchi Y, Kakushima N, Yamamichi N, Fujishiro M

With increasing global life expectancy, the significance of geriatric assessment parameters has increased. Sarcopenia is a crucial assessment parameter and is defined as the age-related loss of muscle mass and...
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Effectiveness of Solution with 5% Detergent for Cleaning Transnasal Esophagogastroduodenoscopy Lens

Komazawa Y, Yuki M, Fukuba N, Kobayashi Y, Ishitobi H, Nakashima S, Nagaoka M, Takahashi Y, Shizuku T

Background/Aims: Unsedated transnasal esophagogastroduodenoscopy (EGD) is affected by a poor scope lens-cleaning function. We have previously reported good, albeit limited, effects of an oolong tea washing solution; here, we evaluated...
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E-learning system to improve the endoscopic diagnosis of early gastric cancer

Yao K, Yao T, Uedo N, Doyama H, Ishikawa H, Nimura S, Takahashi Y

We developed three e-learning systems for endoscopists to acquire the necessary skills to improve the diagnosis of early gastric cancer (EGC) and demonstrated their usefulness using randomized controlled trials. The...
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Arteriovenous Fistula at the Craniocervical Junction Found After Cervical Laminoplasty for Ossification of the Posterior Longitudinal Ligament

Sasada S, Hiramatsu M, Kusumegi A, Fujimura H, Oshikata S, Takahashi Y, Nishida K, Yasuhara T, Date I

Ossification of the posterior longitudinal ligament (OPLL) is common in East Asia. Arteriovenous fistula at the craniocervical junction (CCJ-AVF), in contrast, is rare. As OPLL occurs most often in the...
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Tailored-dose chemotherapy with gemcitabine and irinotecan in patients with platinum-refractory/resistant ovarian or primary peritoneal cancer: a phase II trial

Tate S, Nishikimi K, Matsuoka A, Otsuka S, Kato K, Takahashi Y, Shozu M

Objective: We investigated the efficacy and toxicity of tailored-dose chemotherapy with gemcitabine and irinotecan for platinum-refractory/resistant ovarian or primary peritoneal cancer. Methods: We enrolled patients with ovarian or primary peritoneal cancer...
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Disc Height Narrowing Could Not Stabilize the Mobility at the Level of Cervical Spondylolisthesis: A Retrospective Study of 83 Patients with Cervical Single-Level Spondylolisthesis

Aoyama R, Yamane J, Ninomiya K, Takahashi Y, Kitamura K, Nori S, Suzuki S, Shiraishi T

Study Design: A retrospective study at a single academic institution. Purpose: We aimed to understand the pathogenesis of cervical spondylolisthesis by analyzing whether narrowing of the disc height stabilizes the slipped...
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Contraindication of Minimally Invasive Lateral Interbody Fusion for Percutaneous Reduction of Degenerative Spondylolisthesis: A New Radiographic Indicator of Bony Lateral Recess Stenosis Using I Line

Ishii K, Isogai N, Shiono Y, Yoshida K, Takahashi Y, Takeshima K, Nakayama M, Funao H

Study Design Retrospective cohort study. Purpose This study aimed to evaluate aggravated lateral recess stenosis and clarify the indirect decompression threshold by combined lateral interbody fusion and percutaneous pedicle screw fixation (LIF/PPS). Overview of...
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Cervical Spinous Process and Its Attached Muscles Maintain Lower Disk Lordosis: A Retrospective Study of 155 Patients Who Underwent Muscle-Preserving Double Laminectomies

Aoyama R, Yamane J, Ninomiya K, Takahashi Y, Kitamura K, Nori S, Suzuki S, Shiraishi T

Study Design: A retrospective study conducted at a single academic institution. Purpose: This study compared the postoperative alignment of consecutive double laminectomies according to their decompression levels and investigated the influence...
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Dynamic Cervical Spinal Canal Stenosis: Identifying Imaging Risk Factors in Extended Positions

Matsumoto S, Aoyama R, Yamane J, Ninomiya K, Takahashi Y, Kitamura K, Nori S, Suzuki S, Anazawa U, Shiraishi T

Study Design: A retrospective study at a single academic institution. Purpose: This study aimed to identify imaging risk factors for stenosis in extended neck positions undetectable in preoperative neutral magnetic resonance...
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