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Stem Cell Properties of Therapeutic Potential

Seo GS

Stem cell research is a innovative technology that focuses on using undifferentiated cells able to self-renew through the asymmetrical or symmetrical divisions. Three types of stem cells have been studied...
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Very small embryonic-like stem-cell optimization of isolation protocols: an update of molecular signatures and a review of current in vivo applications

Shin DM, Suszynska , Mierzejewska K, Ratajczak , Ratajczak

  • KMID: 2154275
  • Exp Mol Med.
  • 2013 Nov;45(11):e56.
As the theory of stem cell plasticity was first proposed, we have explored an alternative hypothesis for this phenomenon: namely that adult bone marrow (BM) and umbilical cord blood (UCB)...
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The New Sysmex XN-2000 Automated Blood Cell Analyzer More Accurately Measures the Absolute Number and the Proportion of Hematopoietic Stem and Progenitor Cells Than XE-2100 When Compared to Flow Cytometric Enumeration of CD34+ Cells

Park SH, Park CJ, Kim MJ, Han MY, Han SH, Cho YU, Jang S

No abstract available.
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Stemness Evaluation of Mesenchymal Stem Cells from Placentas According to Developmental Stage: Comparison to Those from Adult Bone Marrow

Sung HJ, Hong SC, Yoo JH, Oh JH, Shin HJ, Choi IY, Ahn KH, Kim SH, Park Y, Kim BS

This study was done to evaluate the stemness of human mesenchymal stem cells (hMSCs) derived from placenta according to the development stage and to compare the results to those from...
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Isolation of neural precursor cells from skeletal muscle tissues and their differentiation into neuron-like cells

Park JS, Kim S, Han DK, Lee JY, Ghil SH

  • KMID: 756071
  • Exp Mol Med.
  • 2007 Aug;39(4):483-490.
Skeletal muscle contains several precursor cells that generate muscle, bone, cartilage and blood cells. Although there are reports that skeletal muscle-derived cells can trans-differentiate into neural-lineage cells, methods for isolating...
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Cross-talk between BubR1 expression and the commitment to differentiate in adipose-derived mesenchymal stem cells

Lee J, Lee CG, Lee KW, Lee CW

BubR1 mitotic checkpoint kinase monitors attachment of microtubules to kinetochores and links regulation of the chromosome-spindle attachment to mitotic checkpoint signaling. Defects in BubR1-mediated signaling severely perturb checkpoint control and...
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Rapid Isolation of Adipose Tissue-Derived Stem Cells by the Storage of Lipoaspirates

Eom YW, Lee JE, Yang MS, Jang IK, Kim HE, Lee DH, Kim YJ, Park WJ, Kong JH, Shim KY, Lee JI, Kim HS

PURPOSE: This study examined a rapid isolation method decreasing the time and cost of the clinical application of adipose tissue-derived stem cells (ASCs). MATERIALS AND METHODS: Aliquots (10 g) of the...
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Enhanced tyrosine hydroxylase expression in PC12 cells co-cultured with feline mesenchymal stem cells

Jin GZ, Yin XJ, Yu XF, Cho SJ, Lee HS, Lee HJ, Kong IK

Mesenchymal stem cells (MSCs) secrete a variety of neuroregulatory molecules, such as nerve growth factor, brain-derived neurotrophic factor, and glial cell-derived neurotrophic factor, which upregulate tyrosine hydroxylase (TH) gene expression...
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In situ tissue regeneration through host stem cell recruitment

Ko IK, Lee SJ, Atala A, Yoo JJ

  • KMID: 2154276
  • Exp Mol Med.
  • 2013 Nov;45(11):e57.
The field of tissue engineering has made steady progress in translating various tissue applications. Although the classical tissue engineering strategy, which involves the use of culture-expanded cells and scaffolds to...
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Roles of gangliosides in mouse embryogenesis and embryonic stem cell differentiation

Kwak DH, Seo BB, Chang KT, Choo YK

Gangliosides have been suggested to play important roles in various functions such as adhesion, cell differentiation, growth control, and signaling. Mouse follicular development, ovulation, and luteinization during the estrous cycle...
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Role of the epithelial-mesenchymal transition and its effects on embryonic stem cells

Kim YS, Yi BR, Kim NH, Choi KC

The epithelial-mesenchymal transition (EMT) is important for embryonic development and the formation of various tissues or organs. However, EMT dysfunction in normal cells leads to diseases, such as cancer or...
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The roles of glycosphingolipids in the proliferation and neural differentiation of mouse embryonic stem cells

Jung JU, Ko K, Lee DH, Ko K, Chang KT, Choo YK

Glycosphingolipids including gangliosides play important regulatory roles in cell proliferation and differentiation. UDP-glucose:ceramide glucosyltransferase (Ugcg) catalyze the initial step in glycosphingolipids biosynthesis pathway. In this study, Ugcg expression was reduced...
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Human Amniotic Fluid Stem Cell-derived Muscle Progenitor Cell Therapy for Stress Urinary Incontinence

Chun SY, Cho DH, Chae SY, Choi KH, Lim HJ, Yoon GS, Kim BS, Kim BW, Yoo JJ, Kwon TG

The most promising treatment for stress urinary incontinence can be a cell therapy. We suggest human amniotic fluid stem cells (hAFSCs) as an alternative cell source. We established the optimum...
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Immunophenotypic Characterization and Quantification of Neoplastic Bone Marrow Plasma Cells by Multiparametric Flow Cytometry and Its Clinical Significance in Korean Myeloma Patients

Cho YU, Park CJ, Park SJ, Chi HS, Jang S, Park SH, Seo EJ, Yoon DH, Lee JH, Suh C

Multiparametric flow cytometry (MFC) allows discrimination between normal and neoplastic plasma cells (NeoPCs) within the bone marrow plasma cell (BMPC) compartment. This study sought to characterize immunophenotypes and quantitate the...
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