- Acute effects of sodium salicylate on concentrations of catecholamine in the perilymph
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Kim SY, Noh KT
- KMID: 1684567
- Korean J Otolaryngol-Head Neck Surg.
- 1992 Dec;35(6):847-861.
No abstract available. -
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- A Case of Bilateral Sudden Hearing Loss and Tinnitus after Salicylate Intoxication
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Kim SM, Jo JM, Baek MJ, Jung KH
- KMID: 2039498
- Korean J Audiol.
- 2013 Apr;17(1):23-26.
- doi: 10.7874/kja.2013.17.1.23
Salicylate, the active ingredient of aspirin can cause sensorineural hearing loss and tinnitus when plasma concentrations reach a critical level. The ototoxic mechanisms of salicylate remain unclear but hearing and... -
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- Sodium salicylate sensitivity in an asthmatic patient with aspirin sensitivity
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Park HS, Lim YS, Suh JE, Rhu NS, Cho DI, Kim JW
- KMID: 1421844
- J Korean Med Sci.
- 1991 Jun;6(2):113-117.
- doi: 10.3346/jkms.1991.6.2.113
Non-acetylated salicylates have been recommended for use as alternatives to nonsteroidal anti-inflammatory drugs (NSAIDs) in aspirin and/or tartrazine-sensitive patients. We experienced a case of an aspirin-sensitive asthmatic patient who developed... -
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- The Effect of Ototoxic Sodium Salicylate on DPOAE and Cochlear Blood Flow in Guinea Pig
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Hwang CH, Chang SO
- KMID: 1887268
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Jun;45(6):544-549.
BACKGROUND AND OBJECTIVES: Salicylate is one of the most commonly prescribed drugs although it has been recognized that salicylate induces hearing loss and tinnitus reversibly. There are many presumed mechanisms... -
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- Effect of Salicylate on DPOAEs and ABRs in Guinea Pigs
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Lee OY, Park YH, Lee SH, Nam BH, Park CI
- KMID: 2275924
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Jul;45(7):646-650.
BACKGROUND AND OBJECTIVES: Salicylates are well-known for producing reversible hearing loss and tinnitus. However, the site and mechanism of salicylate ototoxicity remain unresolved. Recent experiments suggest that reversible biochemical and/or... -
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- A Case of Acute Generalized Exanthematous Pustulosis Induced by Sodium Salicylate
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- KMID: 2299494
- Korean J Asthma Allergy Clin Immunol.
- 2011 Dec;31(4):304-306.
BACKGROUND: Acute generalized exanthematous pustulosis (AGEP) is a rare disease mostly related to drug eruption. The skin lesions present as widespread sterile pustules on erythematous bases, usually accompanied by fever... -
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- A Case of Bilateral Sensorineural Hearing Loss after Salicylate Intoxication
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Lee HN, Kang WS, Song HY, Chung JW
- KMID: 2277180
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2010 Dec;53(12):798-801.
- doi: 10.3342/kjorl-hns.2010.53.12.798
Salicylates, such as aspirin, are considered the most commonly used medicine in Korea for its anti-inflammatory, anti-pyretic, and analgesic properties. In spite of its wide range of benefits, aspirin produces... -
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- Acute Sensorineural Hearing Loss and Tinnitus with Aspirin: A Case Report
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Cho H, Kwon JH, Seo HJ
- KMID: 2316773
- Res Vestib Sci.
- 2009 Jun;8(1):74-76.
Salicylate (aspirin) causes ototoxic side effects in some patients, such as bilateral mild to moderate sensorineural hearing loss and tinnitus although its ototoxic mechanisms still remain largely unclear. We report... -
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- Neurotoxicity of Sodium Salicylate on Spinal Sensory Neurons in Culture
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Lee KC, Choi YS, Park ST
- KMID: 2335944
- J Korean Pain Soc.
- 2001 Dec;14(2):136-141.
BACKGROUND: Sodium salicylate (SS) is a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of neuralgia or pain from rheumatoid arthritis. When abused or used in excess, SS can induce cytotoxicity.... -
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- Salicylate Regulates Cyclooxygenase-2 Expression through ERK and Subsequent NF-kappaB Activation in Osteoblasts
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Chae HJ, Lee JK, Byun JO, Chae SW, Kim HR
- KMID: 2285293
- Korean J Physiol Pharmacol.
- 2003 Aug;7(4):239-246.
The expression of cyclooxygenase-2 (COX-2) is a characteristic response to inflammation and can be inhibited with sodium salicylate. TNF-alpha plus IFN-gamma can induce extracellular signal-regulated kinase (ERK), IKK, IkappaB degradation... -
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- LPS-induced Chemokine Gene Expression in Mesangial Cell
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Rim H, Yoon SJ, Park JW
- KMID: 2307275
- Korean J Nephrol.
- 1999 Nov;18(6):847-855.
This study was designed to investigate the mole- cular mechanism of chemokine induction by lipopoly-saccharide(LPS) of E. coli. Chemokine gene expression was evaluated by the reverse transcriptase-polymerase chain reaction(RT-PCR) assay... -
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- Inflammation and Insulin Resistance: An Old Story with New Ideas
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Kim JK
- KMID: 2222368
- Korean Diabetes J.
- 2010 Jun;34(3):137-145.
- doi: 10.4093/kdj.2010.34.3.137
Years before insulin was discovered, anti-inflammatory sodium salicylate was used to treat diabetes in 1901. Intriguingly for many years that followed, diabetes was viewed as a disorder of glucose metabolism,... -
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- Suppression of iNOS Expression by NSAIDs and Acetaminophen in Vascular Smooth Muscle Cells
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Jo HJ, Choi HC, Lee KY, Ha JH, Jo HC
- KMID: 2204430
- J Korean Soc Vasc Surg.
- 2004 May;20(1):24-29.
PURPOSE: iNOS expression in vascular smooth muscle cells (VSMC) causes the development of septic shock, and multiple organ dysfunction syndrome (MODS). For the inhibition of iNOS expression, glucocorticoids are known... -
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- Effect of Ginkgo Biloba Extract on N-Methyl-D-Aspartic Acid Receptor Subunit 2B Expression in a Salicylate-Induced Ototoxicity Model
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Lee SY, Han SY, Shim YJ, Han JJ, Cho D, Kim JE, Kim YH
- KMID: 2447425
- Clin Exp Otorhinolaryngol.
- 2019 May;12(2):169-175.
- doi: 10.21053/ceo.2018.00983
OBJECTIVES.: Sodium salicylate (SS) is well known for its ototoxic properties that induce functional and morphological changes in the cochlea and brain. Ginkgo biloba extract (GBE) has been widely used... -
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- Effect of Anti - inflammatory Drugs on the Degradation of Hyaluronate and Collagen by Reactive Oxygen Species
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Lee EW, Lee SH, Yim H, Lee KS, Chung MH
- KMID: 2446537
- J Korean Orthop Assoc.
- 1984 Oct;19(5):789-797.
- doi: 10.4055/jkoa.1984.19.5.789
Leukocytes, when subjected to phagocytic, immunologic or chemical stimuli, are known to exhibit a sequence of morphological and biochemical events which lead to the production of Hâ‚‚, Oâ‚‚, Oâ‚‚â», and... -
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- Antioxidant effect of lidocaine and procaine on reactive oxygen species-induced endothelial dysfunction in the rabbit abdominal aorta
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Lee JM, Suh JK, Jeong JS, Cho SY, Kim DW
- KMID: 1766371
- Korean J Anesthesiol.
- 2010 Aug;59(2):104-110.
- doi: 10.4097/kjae.2010.59.2.104
BACKGROUND: Reactive oxygen species (ROS) induce lipid peroxidation and tissue damage in the endothelium. We tested the antioxidant effect of lidocaine and procaine on ROS-induced endothelial damage in the rabbit... -
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- Effect of ketorolac and diclofenac on the impairment of endothelium-dependent relaxation induced by reactive oxygen species in rabbit abdominal aorta
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Lee SY, Suh JK, Choi JH, Jeon WJ, Cheong MA
- KMID: 2239777
- Korean J Anesthesiol.
- 2010 Sep;59(3):196-202.
- doi: 10.4097/kjae.2010.59.3.196
BACKGROUND: Reactive oxygen species (ROS) induce lipid peroxidation and tissue damage in endothelium. We studied the influences of ketorolac and diclofenac on ROS effects using the endothelium of rabbit abdominal... -
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