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Androgen Receptor as a Predictive Marker for Pathologic Complete Response in Hormone Receptor–Positive and HER-2–Negative Breast Cancer with Neoadjuvant Chemotherapy

Lee EG, Lee DE, Kim Hh, Han JH, Lee S, Kang HS, Lee ES, Chae H, Sim SH, Lee KS, Kwon Y, Jung SY

Purpose This study investigated pathological complete response (pCR) according to androgen receptor (AR) in breast cancer patients undergoing neoadjuvant chemotherapy and estimated the relationship between AR expression and clinicopathological factors. Materials...
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Impacts of Subtype on Clinical Feature and Outcome of Male Breast Cancer: Multicenter Study in Korea (KCSG BR16-09)

Lee J, Lee KS, Sim SH, Chae H, Sohn J, Kim GM, Lee KH, Kang SH, Jung KH, Jeong Jh, Byun JH, Koh SJ, Lee KE, Lim S, Kim HJ, Won HS, Park HS, Lee GJ, Hong S, Baek SK, Lee SI, Choi MY, Woo IS

Purpose The treatment of male breast cancer (MBC) has been extrapolated from female breast cancer (FBC) because of its rarity despite their different clinicopathologic characteristics. We aimed to investigate the...
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Types of Perception Toward Quarantine Measures among Patients Infected with COVID-19

Kim GM, Lee JU, Jung HK, Nam SG, Sim SH, Chang SJ

Purpose: This study was conducted to identify the types of perception toward quarantine measures at hospitals or community treatment centers among patients infected with COVID-19. Methods: This study applied Q-methodology....
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Underutilisation of Physical Rehabilitation Therapy by Cancer Patients in Korea: a Population-based Study of 958,928 Korean Cancer Patients

Cho S, Chung SH, Kang M, Jo A, Sim SH, Kim YJ, Yang EJ

Background: Advanced cancers are associated with more severe symptoms and greater impairment. Although most patients with metastatic cancer would benefit from rehabilitation, few patients receive appropriate rehabilitation therapy. We explored...
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Guidelines for Cancer Care during the COVID-19 Pandemic in South Korea

Lee JB, Jung M, Kim JH, Kim BH, Kim Y, Kim YS, Kim BC, Kim J, Moon SH, Park KU, Park M, Park HJ, Sim SH, Yoon HM, Lee SJ, Lee E, Chun JY, Chung YK, Jung SY, Chung J, Lee ES, Chung HC, Yun T, Rha SY

At the end of 2019, the cause of pneumonia outbreaks in Wuhan, China, was identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In February 2020, the World Health...
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Palbociclib Plus Fulvestrant in Korean Patients from PALOMA-3 With Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer

Kim JH, Im SA, Sim SH, Bananis E, Huang X, Kim HS, Kim SB

In the PALOMA-3 trial, the median progression-free survival (PFS) was longer among patients with hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2−) advanced breast cancer (ABC) treated with palbociclib...
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Supervised Physical Rehabilitation in the Treatment of Patients with Advanced Cancer: a Systematic Review and Meta-analysis

Yang J, Choi M, Choi J, Kang M, Jo A, Chung SH, Sim SH, Kim YJ, Yang EJ, Yu SY

Background: As the survival rate of cancer patients increases, the clinical importance of rehabilitation provided by healthcare professionals also increases. However, the evidence supporting the relevance of rehabilitation programs is...
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Unplanned change from double free flap to a chimeric anterolateral thigh flap in recurrent laryngeal cancer

Ki SH, Ma SH, Sim SH, Choi MS

Reconstruction method choice in recurrent head and neck cancer depends on surgical history, radiation therapy dosage, conditions of recipient vessels, and general patient condition. Furthermore, when defects are multiple or...
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Subcutaneous Heterotopic Ossification Suspected as Skin Cancer

Ki SH, Sim SH, Ma SH

Skin ulcerations on old scars such as post-burn scar contractures are often suspected to be skin cancer. A 68-year-old woman with a 2-year-old skin ulceration, 1 cm in diameter, on...
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Randomized Open Label Phase III Trial of Irinotecan Plus Capecitabine versus Capecitabine Monotherapy in Patients with Metastatic Breast Cancer Previously Treated with Anthracycline and Taxane: PROCEED Trial (KCSG BR 11-01)

Park IH, Im SA, Jung KH, Sohn JH, Park YH, Lee KS, Sim SH, Park KH, Kim JH, Nam BH, Kim HJ, Kim TY, Lee KH, Kim SB, Ahn JH, Lee S, Ro J

PURPOSE: We investigated whether irinotecan plus capecitabine improved progression-free survival (PFS) compared with capecitabine alone in patients with human epidermal growth factor 2 (HER2) negative and anthracycline and taxane pretreated...
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Bilateral Vulvar Reconstruction Using Two Different Types of Perforator Flap: A Case Report

Ki SH, Sim SH, Lee SH

We reconstructed an extensive vulvar defect with the internal pudendal artery and the anterior obturator artery perforator flap and compared the two types of flaps. A 57-year-old female patient had...
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A Rare Case of Phyllodes Tumor Metastasis to the Stomach Presenting as Anemia

Choi DI, Chi HS, Lee SH, Kwon Y, Park SY, Sim SH, Park IH, Lee KS

Metastasis of a phyllodes tumor to the stomach is an extremely rare condition with important clinical implications. A 44-year-old woman was initially diagnosed with a phyllodes tumor in her right...
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Gefitinib-Induced Interstitial Lung Disease in Korean Lung Cancer Patients

Beom SH, Kim DW, Sim SH, Keam B, Park JH, Lee JO, Kim TM, Lee SH, Heo DS

PURPOSE: Interstitial lung disease (ILD) is a serious adverse effect of gefitinib. We examined the incidence and clinical characteristics of drug-induced ILD in Korean non-small cell lung carcinoma patients treated...
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Reconstructive Trends in Post-Ablation Patients with Esophagus and Hypopharynx Defect

Ki SH, Choi JH, Sim SH

The main challenge in pharyngoesophageal reconstruction is the restoration of swallow and speech functions. The aim of this paper is to review the reconstructive options and associated complications for patients...
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Application of Cancer Genomics to Solve Unmet Clinical Needs

Lee SH, Sim SH, Kim JY, Cha S, Song A

The large amount of data on cancer genome research has contributed to our understanding of cancer biology. Indeed, the genomics approach has a strong advantage for analyzing multi-factorial and complicated...
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A Case of Meningococcal Sepsis and Meningitis with Complement 7 Deficiency in a Military Trainee

Sim SH, Heo JY, Kim EC, Choe KW

  • KMID: 2391845
  • Infect Chemother.
  • 2013 Mar;45(1):94-98.
Complement component 7 (C7) deficiency leads to the loss of complement lytic function, and affected patients show increased susceptibility to encapsulated organisms infection, especially Neisseria meningitidis. Recently, we have experienced...
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Comparison of Physicians and Nurses' Attitudes toward Family Presence during Cardiopulmonary Resuscitation

Cho JL, Lee EN, Sim SH, Lee NY

  • KMID: 2298279
  • Korean J Adult Nurs.
  • 2013 Feb;25(1):41-52.
PURPOSE: The purpose of this study was to compare the attitude of physicians and nurses toward family presence during cardiopulmonary resuscitation (CPR). METHODS: 100 physicians and 100 nurses from five hospitals...
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Perception of Physicians and Nurses on Presence of Family during Invasive Procedures

Sim SH, Lee EN

PURPOSE: The purpose of this descriptive study was to determine the perception of physicians and nurses on family presence during invasive procedures. METHODS: The study population consisted of 100 physicians...
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Two cases of thyroid small cell carcinoma

Sim SH, Kim HJ, Kim MJ, Cha Y, Lee YS, Lim KH, Lee SH

  • KMID: 2258582
  • Korean J Med.
  • 2009 Aug;77(2):241-245.
Historically, small cell carcinoma in the thyroid has been regarded as a kind of lymphoma and small cell carcinoma in the thyroid as a distinct disease entity is still controversial....
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Sunitinib-induced reversible posterior leukoencephalopathy syndrome after rifampin discontinuation

Kim MJ, Kim HJ, Bae HM, Sim SH, Lee JO, Cha Y, Lee SH

  • KMID: 2258140
  • Korean J Med.
  • 2009 Aug;77(Suppl 1):S188-S191.
Sunitinib is an oral tyrosine kinase inhibitor with anti-angiogenic activity that is used for the treatment of advanced renal cell carcinoma and advanced gastrointestinal stromal tumors after failure on imatinib....
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