Korean J Med.  2009 Aug;77(2):241-245.

Two cases of thyroid small cell carcinoma

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. shlee119@snu.ac.kr

Abstract

Historically, small cell carcinoma in the thyroid has been regarded as a kind of lymphoma and small cell carcinoma in the thyroid as a distinct disease entity is still controversial. Here, we present two cases of thyroid small cell carcinoma that were differentiated from lymphoma, based on immunohistochemical staining. One case was misdiagnosed as anaplastic carcinoma that occurred during the treatment of follicular carcinoma. Both cases responded well to chemotherapy. These cases support the hypothesis that thyroid small cell carcinoma is a distinct disease entity. One should consider small cell carcinoma when there is a rapidly growing mass in the thyroid.

Keyword

Thyroid cancer; Small cell carcinoma

MeSH Terms

Carcinoma
Carcinoma, Small Cell
Lymphoma
Thyroid Gland
Thyroid Neoplasms
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