Cancer Res Treat.  2017 Jul;49(3):846-849. 10.4143/crt.2016.188.

A Rare Case of Phyllodes Tumor Metastasis to the Stomach Presenting as Anemia

Affiliations
  • 1Department of Internal Medicine, National Cancer Center Hospital, Goyang, Korea. kslee@ncc.re.kr
  • 2Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
  • 3Department of Pathology, Research Institute and Hospital, National Cancer Center, Goyang, Korea.

Abstract

Metastasis of a phyllodes tumor to the stomach is an extremely rare condition with important clinical implications. A 44-year-old woman was initially diagnosed with a phyllodes tumor in her right breast in 2008, and subsequently presented to an out-patient clinic with dizziness on December 16, 2013. We found that she had severe anemia (hemoglobin levels, 6.7 g/dL), and we quickly performed esophagogastroduodenoscopy to identify the cause. This procedure revealed large ulcerofungating masses with active bleeding in the stomach. Histopathological examination revealed that the masses were consistent with phyllodes tumor metastases. In patients with a metastatic phyllodes tumor presenting as anemia, gastric metastasis should be considered as one of the differential diagnoses because overlooking the possibility might have dire consequences if cytotoxic chemotherapy were administered.

Keyword

Phyllodes tumor; Stomach; Neoplasm metastasis; Anemia

MeSH Terms

Adult
Anemia*
Breast
Diagnosis, Differential
Dizziness
Drug Therapy
Endoscopy, Digestive System
Female
Hemorrhage
Humans
Neoplasm Metastasis*
Outpatients
Phyllodes Tumor*
Stomach*
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