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Characterization of a Septobasidium sp. Associated with Felt Disease of Schisandra chinensis

Choi IY, Lee WH, Lee JJ, Park MJ, Ko JA, Choi JR, Shin HD

Extensive disease surveys performed during the summers of 2013 and 2014 in Schisandra chinensis orchards resulted in the finding of a Septobasidium sp. associated with felt disease. The fungus was...
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Lignans with NADPH Oxidase 2 (NOX2)-inhibitory Activity from the Fruits of Schisandra chinensis

Park JM, Pel P, Chin YW, Lee MY

An isoform of NADPH oxidase (NOX), NOX2 is a superoxide-generating enzyme involved in diverse pathophysiological events. Although its potential as a therapeutic target has been validated, there is no clinically...
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Activation of transient receptor potential vanilloid 3 by the methanolic extract of Schisandra chinensis fruit and its chemical constituent γ-schisandrin

Nam Y, Kim HJ, Kim YM, Chin YW, Kim YK, Bae HS, Nam JH, Kim WK

Transient receptor potential vanilloid 3 (TRPV3) is a non-selective cation channel with modest permeability to calcium ions. It is involved in intracellular calcium signaling and is therefore important in processes...
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Schisandra Chinensis Baillon regulates the gene expression of phase II antioxidant/detoxifying enzymes in hepatic damage induced rats

Jang HI, Do GM, Lee HM, Ok HM, Shin JH, Kwon O

  • KMID: 2313739
  • Nutr Res Pract.
  • 2014 Jun;8(3):272-277.
BACKGROUND/OBJECTIVES: This study investigated the antioxidant activities and hepatoprotective effects of Schisandra chinensis Baillon extract (SCE) against tert-butyl hydroperoxide (t-BHP)-induced oxidative hepatic damage in rats. MATERIALS/METHODS: Sprague-Dawley (SD) rats were pretreated...
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Effects of Schisandra chinensis fruit extract and gomisin A on the contractility of penile corpus cavernosum smooth muscle: a potential mechanism through the nitric oxide - cyclic guanosine monophosphate pathway

Choi BR, Kim HK, Park JK

BACKGROUND/OBJECTIVES: This study evaluated the effects and molecular mechanisms of the Schisandra chinensis fruit extract (SC) and its major compound gomisin A (GA), on the contractility of rabbit penile corpus...
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Schisantherin B Improves the Pathological Manifestations of Mice Caused by Behavior Desperation in Different Ages-Depression with Cognitive Impairment

Xu M, Xiao F, Wang M, Yan T, Yang H, Wu B, Bi K, Jia Y

Depression is a major mood disorder. Abnormal expression of glial glutamate transporter-1 (GLT-1) is associated with depression. Schisantherin B (STB) is one bioactive of lignans isolated from Schisandra chinensis (Turcz.)...
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α-Isocubebene modulates vascular tone by inhibiting myosin light chain phosphorylation in murine thoracic aorta

Ye BH, Kim EJ, Baek SE, Choi YW, Park SY, Kim CD

α-Iso-cubebene (ICB) is a dibenzocyclooctadiene lignin contained in Schisandra chinensis (SC), a well-known medicinal herb that ameliorates cardiovascular symptoms, but the mechanism responsible for this activity has not been determined....
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Comparison of anti-oxidant activities of seventy herbs that have been used in Korean traditional medicine

Ko SH, Choi SW, Ye SK, Yoo S, Kim HS, Chung MH

  • KMID: 2313363
  • Nutr Res Pract.
  • 2008 Sep;2(3):143-151.
Many herbs have been used as therapeutics in Korean traditional medicine. In view of their clinical indications, anti-oxidant activity may contribute to their pharmacological effects. However, anti-oxidant information on these...
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A Systematic Review and Meta-analysis on the Effect of Herbal Medicine to Manage Sleep Dysfunction in Peri- and Postmenopause

Khadivzadeh T, Abdolahian S, Ghazanfarpour M, Kargarfard L, Dizavandi , Khorsand I

OBJECTIVES: Some conventional medications used to treat insomnia, such as benzodiazepine, non-benzodiazepine, and hormone therapy, are associated with side effects. Therefore, there is a growing interest in the use of...
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Inhibition of Adenosine Triphosphate-stimulated Mucin Secretion from Airway Epithelial Cells by Schizandrin

Heo HJ, Lee HJ, Kim C, Bae KH, Kim YS, Kang SS, Park YC, Kim YH, Seo UK, Seok JH

  • KMID: 2071633
  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):251-254.
Schizandrae Fructus has been used for controlling respiratory allergic or inflammatory diseases in folk medicine and their components, schizandrin, schizandrin-A and gomisin-A were reported to have diverse biological effects. In...
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Effects of Sour Tastes on Blood Components in Anemic mice - Animal Experiment for Nursing Intervention of Female Anemia -

Shin HS, Kim SW

  • KMID: 2296868
  • J Korean Acad Nurs.
  • 2001 Apr;31(2):268-278.
Many women in the world have suffered from anemia produced by menstruation, pregnancy and delivery. In the theory of oriental medicine, a sour taste is believed to have a tonic...
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The New Phytoformula Containing Morus alba, Schizandra sinensis and Asparagus cochinchinensis Inhibits Lung Inflammation in vitro and in vivo

Jeong HG, Lee CW, Lee JH, Kim SJ, Kwon YS, Heo Y, Kim HP

A phytoformula containing the root barks of Morus alba, the fructus of Schizandra sinensis and the roots of Asparagus cochinchinensis (MSA) was prepared as a potential new herbal remedy, and...
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Regulation of Inflammatory Repertoires and NF-kappaB Signal Transduction by DDB, an Active Compound from Schizandra Chinensis Baillon

Joo SS, Yoo YM, Won TJ, Kim MJ, Lee SG, Hwang KW, Lee DI

BACKGROUND: Chronic inflammation in the brain has known to be associated with the development of a various neurological diseases including dementia. In general, the characteristic of neuro-inflammation is the activated...
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Suppressive effects of Schizandra chinensis Baillon water extract on allergy-related cytokine generation and degranulation in IgE-antigen complex-stimulated RBL-2H3 cells

Chung MJ, Kim JM, Lee S, Kim T, Kim D, Baek J, Kim T, Lee J, Kim K, Yoon JA, Choe M

  • KMID: 2313580
  • Nutr Res Pract.
  • 2012 Apr;6(2):97-105.
Schizandra chinensis Baillon is a traditional folk medicine plant that is used to treat and prevent several inflammatory diseases and cancer in Korea, but the underlying mechanisms involved in its...
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