- New daily persistent headache with isolated sphenoiditis in children
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Lee J, Rhee M, Suh ES
- KMID: 2140677
- Korean J Pediatr.
- 2015 Feb;58(2):73-76.
- doi: 10.3345/kjp.2015.58.2.73
Isolated sphenoid sinusitis is a rare disease in children, and its symptoms are often nonspecific and confusing. Rarely, severe headache can be the first or only symptom of isolated sphenoid... -
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- Generation of Insulin-Expressing Cells in Mouse Small Intestine by Pdx1, MafA, and BETA2/NeuroD
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Lee SH, Rhee M, Kim JW, Yoon KH
- KMID: 2392484
- Diabetes Metab J.
- 2017 Oct;41(5):405-416.
- doi: 10.4093/dmj.2017.41.5.405
BACKGROUND: To develop surrogate insulin-producing cells for diabetes therapy, adult stem cells have been identified in various tissues and studied for their conversion into β-cells. Pancreatic progenitor cells are derived... -
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- Lipid Variability Induces Endothelial Dysfunction by Increasing Inflammation and Oxidative Stress
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Rhee M, Lee J, Lee EY, Yoon KH, Lee SH
- KMID: 2556643
- Endocrinol Metab.
- 2024 Jun;39(3):511-520.
- doi: 10.3803/EnM.2023.1915
Background: This study investigates the impact of fluctuating lipid levels on endothelial dysfunction. Methods: Human aortic and umbilical vein endothelial cells were cultured under varying palmitic acid (PA) concentrations: 0, 50,... -
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- Reversal of Hypoglycemia Unawareness with a Single-donor, Marginal Dose Allogeneic Islet Transplantation in Korea: A Case Report
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Yang HK, Ham DS, Park HS, Rhee M, You YH, Kim MJ, Kim JW, Lee SH, Hong TH, Choi BG, Cho JH, Yoon KH
- KMID: 2164488
- J Korean Med Sci.
- 2015 Jul;30(7):991-994.
- doi: 10.3346/jkms.2015.30.7.991
Pancreatic islet transplantation is a physiologically advantageous and minimally invasive procedure for the treatment of type 1 diabetes mellitus. Here, we describe the first reported case of successful allogeneic islet... -
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- Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells
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You YH, Ham DS, Park HS, Rhee M, Kim JW, Yoon KH
- KMID: 2281710
- Diabetes Metab J.
- 2011 Apr;35(2):119-129.
- doi: 10.4093/dmj.2011.35.2.119
BACKGROUND: A limitation in the number of insulin-producing pancreatic beta-cells is a special feature of diabetes. The identification of alternative sources for the induction of insulin-producing surrogate beta-cells is a... -
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- PDX-1/VP16 Overexpression Induce the Transdifferentiation of Canine Adult Pancreatic Cells into Beta-cells
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You YH, Park SC, Lee SH, Park HS, Ham DS, Rhee M, Kim JW, Song KH, Yoon KH
- KMID: 2008096
- J Korean Diabetes Assoc.
- 2007 Jan;31(1):51-62.
- doi: 10.4093/jkda.2007.31.1.51
BACKGROUND: A major obstacle of islet transplantation is an inadequate supply of insulin-producing tissue. Ad-PDX-1/VP16 overexpression and Exendin-4 treatment have been proved the effects on differentiation and proliferation of pancreatic... -
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- Association of the magnitude of the difference in blood pressure between office and ambulatory measurements with blood pressure variability in untreated individuals
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Lee Y, Rhee M, Kim J, Do U, Kim J, Kim B, Kim H
- KMID: 2536728
- Clin Hypertens.
- 2022;28(1):36.
- doi: 10.1186/s40885-022-00220-7
Objectives: We evaluated the association between cardiovascular risk factors and the magnitude of the difference in systolic blood pressure (SBP) between office and ambulatory measurements (masked effect) in untreated individuals... -
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- A novel BTK gene mutation, c.82delC (p.Arg28 Alafs*5), in a Korean family with X-linked agammaglobulinemia
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Lee J, Rhee M, Min TK, Bang HI, Jang MA, Kang ES, Kim HJ, Yang HJ, Pyun BY
- KMID: 2362254
- Korean J Pediatr.
- 2016 Nov;59(Suppl 1):S49-S52.
- doi: 10.3345/kjp.2016.59.11.S49
X-linked agammaglobulinemia (XLA) is a hereditary humoral immunodeficiency that results from Bruton’s tyrosine kinase (BTK) gene mutations. These mutations cause defects in B-cell development, resulting in the virtual absence of... -
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- Differentiation of Microencapsulated Neonatal Porcine Pancreatic Cell Clusters in Vitro Improves Transplant Efficacy in Type 1 Diabetes Mellitus Mice
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Cheon GJ, Park HS, Lee EY, Kim MJ, You YH, Rhee M, Kim JW, Yoon KH
- KMID: 2533637
- Diabetes Metab J.
- 2022 Sep;46(5):677-688.
- doi: 10.4093/dmj.2021.0202
Background: Neonatal porcine pancreatic cell clusters (NPCCs) have been proposed as an alternative source of β cells for islet transplantation because of their low cost and growth potential after transplantation.... -
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- Suppression of Fibrotic Reactions of Chitosan-Alginate Microcapsules Containing Porcine Islets by Dexamethasone Surface Coating
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Kim MJ, Park HS, Kim JW, Lee EY, Rhee M, You YH, Khang G, Park CG, Yoon KH
- KMID: 2513298
- Endocrinol Metab.
- 2021 Feb;36(1):146-156.
- doi: 10.3803/EnM.2021.879
Background: The microencapsulation is an ideal solution to overcome immune rejection without immunosuppressive treatment. Poor biocompatibility and small molecular antigens secreted from encapsulated islets induce fibrosis infiltration. Therefore, the aims... -
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- Developing a Tool to Assess Competency to Consent to Psychiatric Hospitalization (KATOC): Reliability and Validity
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Seo MK, Kim SH, Rhee M
- KMID: 2315926
- Psychiatry Investig.
- 2011 Mar;8(1):39-48.
OBJECTIVE: The justification of informed consent requires that a patient be provided with the information necessary for deciding treatment and able to use such information based on reasonable thinking. The... -
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- Serum Betatrophin Concentrations and the Risk of Incident Diabetes: A Nested Case-Control Study from Chungju Metabolic Disease Cohort
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Lee SH, Rhee M, Kwon HS, Park YM, Yoon KH
- KMID: 2409186
- Diabetes Metab J.
- 2018 Feb;42(1):53-62.
- doi: 10.4093/dmj.2018.42.1.53
BACKGROUND: Betatrophin is a newly identified hormone derived from the liver and adipose tissue, which has been suggested to regulate glucose and lipid metabolism. Circulating levels of betatrophin are altered... -
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- Characterization of Preadipocyte factor-1 (Pref-1) Expressing Pancreatic Cells
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Rhee M, Suh SH, Yang YJ, Kim JW, Jeon SY, Hong OK, Ko SH, Choi YH, Cha BY, Son HY, Yoon KH
- KMID: 2177738
- J Korean Diabetes Assoc.
- 2005 Nov;29(6):507-516.
BACKGROUND: Preadipocyte factor-1/Delta-like 1(Pref-1/Dlk1) is a type I membrane protein that has six epidermal growth factor (EGF)-like repeats in its extracellular and a short cytoplasmic domain. It is widely expressed... -
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- STEP signaling pathway mediates psychomotor stimulation and morphine withdrawal symptoms, but not for reward, analgesia and tolerance
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Kim YJ, Kang Y, Park HY, Lee JR, Yu DY, Murata T, Gondo Y, Hwang JH, Kim YH, Lee CH, Rhee M, Han PL, Chung BH, Lee HJ, Kim KS
- KMID: 2361499
- Exp Mol Med.
- 2016 Feb;48(2):e212.
- doi: 10.1038/emm.2016.1
Striatal-enriched protein tyrosine phosphatase (STEP) is abundantly expressed in the striatum, which strongly expresses dopamine and opioid receptors and mediates the effects of many drugs of abuse. However, little is... -
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- A randomized, double‑blind, multicenter, phase III study on the efficacy and safety of a combination treatment involving fimasartan, amlodipine, rosuvastatin in patients with essential hypertension and dyslipidemia who fail to respond adequately to fimasartan monotherapy
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Jeon E, Lim S, Kim S, Yang H, Kim M, Rhee M, Han S, Shin J, Kim K, Jeong J, Sung K, Hong G, Kim H, Kwon K, Kang T, Lee H, Han S
- KMID: 2536407
- Clin Hypertens.
- 2022;28(1):40.
- doi: 10.1186/s40885-022-00223-4
Background: To assess the efficacy and safety of a combination therapy involving fimasartan, amlodipine, and rosuv‑ astatin in patients with essential hypertension and dyslipidemia who fail to respond to fimasartan... -
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