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Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome

Yoo JR, Kim SH, Kim YR, Lee KH, Oh WS, Heo ST

BACKGROUND/AIMS: Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever with a high fatality rate. However, effective treatments for SFTS cases not responded to supportive therapy have not...
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Co-Infection of Scrub Typhus and Human Granulocytic Anaplasmosis in Korea, 2006

Kim JH, Lee CS, Moon C, Kwak YG, Kim BN, Kim ES, Kang JM, Park WB, Oh MD, Park SW

BACKGROUND: Scrub typhus, severe fever with thrombocytopenia syndrome (SFTS) and human granulocytic anaplasmosis (HGA) are important arthropod-borne infectious diseases in Korea and share a common point that they are transmitted...
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Genetic identification of astroviruses in wild boars

Vilcek S, Salamunova S, Jackova A

Astroviruses are widely detected in pigs but their detection in wild boars is rather sporadic. In this study, astroviruses were detected in organ homogenates of wild boars by applying nested...
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Reconsideration of Diagnostic Lumbar Puncture in Childhood Enteroviral Meningitis

Nam JW, Kim TS, Kim JY, Kim JS

PURPOSE: Despite the fact that enteroviral meningitis is the most common cause of meningitis in children with signs of meningeal irritation and has benign course, most clinicians routinely perform an...
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Angiopoietin-1 and -2 and vascular endothelial growth factor expression in ovarian grafts after cryopreservation using two methods

Cho IA, Lee YJ, Lee HJ, Choi IY, Shin JK, Lee SA, Lee JH, Choi WJ

OBJECTIVE: The favored method of preserving fertility in young female cancer survivors is cryopreservation and autotransplantation of ovarian tissue. Reducing hypoxia until angiogenesis takes place is essential for the survival...
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The Factors Affecting the Use of Empirical Antibiotics in Febrile Infants from 1 Month to Less than 3 Months

Byun JH, Song BK, Kim YA, Ko H, Yoo SD, Lim TJ, Park SE

PURPOSE: This study investigated the factors affecting the use of empirical antibiotics in febrile infants from 1 month to less than 3 months. METHODS: We retrospectively reviewed the medical records of...
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Dysregulation of GABAergic Signalling Contributes in the Pathogenesis of Diarrhea-predominant Irritable Bowel Syndrome

Aggarwal S, Ahuja V, Paul J

  • KMID: 2417387
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):422-430.
  • doi: 10.5056/jnm17100
BACKGROUND/AIMS: Diarrhea-predominant irritable bowel syndrome (IBS-D) is a prevalent functional bowel disorder. Abdominal pain, discomfort and altered intestinal habits are the salient features of IBS-D. Low grade inflammation and altered...
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Comparative Analysis of Platelet-rich Plasma Effect on Tenocytes from Normal Human Rotator Cuff Tendon and Human Rotator Cuff Tendon with Degenerative Tears

Yoon JY, Lee SY, Shin S, Yoon KS, Jo CH

BACKGROUND: Platelet-rich plasma (PRP) stimulates cell proliferation and enhances matrix gene expression and synthesis. However, there have been no comparative study of the PRP effect on the normal and degenerative...
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Long Non-Coding RNA TUG1 Promotes Proliferation and Inhibits Apoptosis of Osteosarcoma Cells by Sponging miR-132-3p and Upregulating SOX4 Expression

Li G, Liu K, Du X

PURPOSE: Long non-coding RNA taurine upregulated gene 1 (TUG1) is reported to be a vital regulator of the progression of various cancers. This study aimed to explore the exact roles...
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Circulating HOTAIR LncRNA Is Potentially Up-regulated in Coronary Artery Disease

Avazpour N, Hajjari M, Yazdankhah S, Sahni A, Foroughmand AM

Coronary artery disease (CAD) is one of the leading causes of death and disability all around the world. Recent studies have revealed that aberrantly regulated long non-coding RNA (lncRNA) as...
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Comparison of R-mix Virus Culture and Multiplex Reverse Transcriptase Polymerase Chain Reaction for Assessment of Neonatal Respiratory Viral Infection

Kim DH, Song JH, Kim SS, Yoo GH, Lee HJ, Kim H

OBJECTIVE: Respiratory viral infection of the neonatal period is highly contagious. Rapid and accurate diagnosis is important for proper treatment and prevention. However, the existing diagnostic method, respiratory virus cell...
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Clinical presentation of croup in children according to causative viruses

Kim GE, Shin SW, Choi HJ, Choi BG

PURPOSE: We evaluated the clinical features of croup in children according to viral etiology. METHODS: This study enrolled pediatric patients with croup, who showed positive results on respiratory virus reverse transcriptase...
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Tibial dyschondroplasia is closely related to suppression of expression of hypoxia-inducible factors 1α, 2α, and 3α in chickens

Huang S, Rehman MU, Qiu G, Luo H, Iqbal MK, Zhang H, Mehmood K, Li J

Tibial dyschondroplasia (TD) cases has not been reported in Tibetan chickens (TBCs), but it is commonly seen in commercial broilers characterized by lameness. The underlying mechanism remains unclear. Hypoxia-inducible factors...
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Comparative proteomic analysis of outer membrane protein 43 (omp43)-deficient Bartonella henselae

Kang JG, Lee HW, Ko S, Chae JS

Outer membrane proteins (OMPs) of Gram-negative bacteria constitute the first line of defense protecting cells against environmental stresses including chemical, biophysical, and biological attacks. Although the 43-kDa OMP (OMP43) is...
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Survey of porcine respiratory disease complex-associated pathogens among commercial pig farms in Korea via oral fluid method

Cheong Y, Oh C, Lee K, Cho KH

Oral fluid analysis for herd monitoring is of interest to the commercial pig production in Korea. The aim of this study was to investigate pathogen-positive rates and correlations among eight...
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Clinical Characteristics of Enteroviral Meningitis without Cerebrospinal Fluid Pleocytosis in Children

Kim NR, Ku JK, Lee BL

PURPOSE: The purpose of this study was to investigate the clinical features and laboratory findings of enteroviral meningitis according to the presence of cerebrospinal fluid (CSF) pleocytosis, and to investigate...
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Epidemiology and Clinical Characteristics of Zika Virus Infections Imported into Korea from March to October 2016

Yoon D, Shin SH, Jang HC, Kim ES, Song EH, Moon SM, Shin SY, Choe PG, Sung JJ, Choi EH, Oh MD, Jee Y, Kim NJ

Zika is a re-emerging, mosquito-borne viral infection, which has been recently shown to cause microcephaly and Guillain-Barré syndrome. Since 2015 the number of infected patients has increased significantly in South...
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p15(Ink4b) Loss of Expression by Promoter Hypermethylation Adds to Leukemogenesis and Confers a Poor Prognosis in Acute Promyelocytic Leukemia Patients

Baba SM, Azad NA, Shah ZA, Dil-Afroze , Pandith AA, Jan A, Aziz SA

PURPOSE: The p15(Ink4b) gene exerts its influence as an inhibitor of cyclin-dependent kinases and is frequently associated with hematological malignancies. Inactivation of this gene through DNA methylation has been found...
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Piezo2: A Candidate Biomarker for Visceral Hypersensitivity in Irritable Bowel Syndrome?

Bai T, Li Y, Xia J, Jiang Y, Zhang L, Wang H, Qian W, Song J, Hou X

  • KMID: 2387837
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):453-463.
  • doi: 10.5056/jnm16114
BACKGROUND/AIMS: Currently, there exists no biomarker for visceral hypersensitivity in irritable bowel syndrome (IBS). Piezo proteins have been proven to play an important role in the mechanical stimulation to induce...
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Estrogen receptor-α, progesterone receptor, and c-erbB/HER-family receptor mRNA detection and phenotype analysis in spontaneous canine models of breast cancer

Kabir FM, DeInnocentes P, Agarwal P, Mill CP, Riese DJ, Bird RC

Well characterized, stable, p16-defective canine mammary cancer (CMT) cell lines and normal canine mammary epithelial cells were used to investigate expression of the major breast cancer-specific hormone receptors estrogen receptor...
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