- Efficient Production of Retroviruses Encoding Human Costimulatory Molecule, B7 - 1 ( CD80 )
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Houh D, Kim TG, Han H, Cho HI, Kim JY, Rooney CM
- KMID: 1548373
- Korean J Immunol.
- 1997 Dec;19(4):481-492.
No abstract available. -
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- Analysis of swine leukocyte antigen class I gene profiles and porcine endogenous retrovirus viremia level in a transgenic porcine herd inbred for xenotransplantation research
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Matczyńska D, Sypniewski D, Gałka S, Sołtysik , Loch T, Nowak E, Smorąg Z, Bednarek I
- KMID: 2412129
- J Vet Sci.
- 2018 May;19(3):384-392.
- doi: 10.4142/jvs.2018.19.3.384
Molecular characterization of swine leukocyte antigen (SLA) genes is important for elucidating the immune responses between swine-donor and human-recipient in xenotransplantation. Examination of associations between alleles of SLA class I... -
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- Role of Cyclic GMP-AMP Synthase in Sensing Human Immunodeficiency Virus
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Park YS, Kim IH, Koh YS
- KMID: 2168696
- J Bacteriol Virol.
- 2014 Jun;44(2):206-207.
- doi: 10.4167/jbv.2014.44.2.206
Cyclic guanosine monophosphate adenosine monophosphate (cGAMP) synthase (cGAS) detects human immunodeficiency virus (HIV) and produces cGAMP to induce cytokines. Reverse transcribed DNA of HIV is critical for triggering innate immune... -
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- Identification of Retroviral Vectors Producing High Viral Titer
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Shin YJ, Lenardo MJ, Park TK, Lee KH
- KMID: 2096737
- J Korean Soc Virol.
- 1999 Mar;29(1):33-38.
Retroviral vector provide a highly efficient method for gene transfer into eukaryotic cells. This vector system can be divided into two components; the retroviral vector itself and the retroviral packaging... -
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- The Efficient Gene Delivery into Human Mesenchymal Stem Cells Using Retroviral Vectors
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Kim SS, Kim BJ, Kim HS
- KMID: 2092807
- Korean J Anat.
- 2003 Oct;36(5):381-387.
Human mesenchymal stem cells (hMSCs) are multipotent stem cells that can differentiate into several mesenchymal lineage cells. In this study, we established an efficient method for gene delivery into these... -
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- Nuclear Factor-kappa B Activation and Chemokine Genes Expression in HT-29 Intestinal Epithelial Cells in Response to Clostridium difficile Toxin A Stimulation
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Lee JY, Yoon YM, Roh HC, Kim JM
- KMID: 1574164
- J Bacteriol Virol.
- 2005 Sep;35(3):217-226.
Intestinal epithelial cells are known to up-regulate the expression of several chemokines in response to bacterial toxins. Since there has been little understanding on the cellular mechanisms of C. difficile... -
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- Expression and Packaging of a Human Endogenous Retrovirus-K Genomic DNA Clone
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Ha-Lee YM
- KMID: 2055032
- J Bacteriol Virol.
- 2006 Dec;36(4):237-245.
- doi: 10.4167/jbv.2006.36.4.237
Human contains large number of human endogenous retroviruses (HERVs) in its genome. One of the HERV families, HERV-K, entered human genome most recently and includes many members with full-length intact... -
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- Comparison of Ectopic Gene Expression Methods in Rat Neural Stem Cells
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Kim W, Kim JH, Kong SY, Park MH, Sohn UD, Kim HJ
- KMID: 1432759
- Korean J Physiol Pharmacol.
- 2013 Feb;17(1):23-30.
- doi: 10.4196/kjpp.2013.17.1.23
Neural stem cells (NSCs) have the ability to proliferate and differentiate into various types of cells that compose the nervous system. To study functions of genes in stem cell biology,... -
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- Effect of Long-term Passage on Liver-specific Functions in Immortalized Hepatocytes with a Temperature-sensitive Mutant of SV40 T Antigen
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Kim BH, Seong SR, Lee WI, Dong SH, Kim HJ, Chang YW, Lee JI, Chang R
- KMID: 2304644
- Korean J Gastroenterol.
- 1999 Jul;34(1):56-68.
BACKGROUND/AIMS: The transcription of liver specific genes decreases dramatically in primary hepatocyte culture. In this study, we evaluated the long-term differentiation of immortalized hepatocytes. METHODS: Immortalized rat hepatocytes were established... -
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- Probing the Utility of Vascular Smooth Muscle Cells as a Target Cell for ex vivo Cardiovascular Gene Therapy
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Byun J, Huh JE, Jung EA, Park SJ, Jeong JO, Gwon HC, Park SW, Kim DK
- KMID: 2227358
- Korean Circ J.
- 2000 Jun;30(6):729-736.
- doi: 10.4070/kcj.2000.30.6.729
BACKGROUND AND OBJECTIVES: Compared to other target cells examined for gene therapy, vascular smooth muscle cells (VSMCs) have the unique advantages including proximity to blood stream and relative abundance in... -
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- The Use of Canine Bone-Marrow Stromal Cell Line, DO64, as Feeder Cells for The Efficient Cloning of Human B Lymphoblastoid Cell Lines ( B-LCLs )
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Kim TG, Han H, Kim YS, Cho HI
- KMID: 1550780
- Korean J Immunol.
- 1999 Jun;21(2):109-113.
Epstein-Barr virus (EBV) is a potent inducer of polyclonal B lymphocyte proliferation and a tool for the establishment of human B lymphoblastoid cell lines (B-LCLs), which have proven useful for... -
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- Establishment of canine kidney cell line for canine distemper virus replication
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Jeon KL, Hwang KK
- KMID: 2169005
- J Biomed Res.
- 2015 Mar;16(1):6-12.
- doi: 10.12729/jbr.2015.16.1.006
Kidney cells of canine embryos were separated into single cells using collagenase and dispase. Primary culture was conducted using these cells. To remove fibroblasts, these cells were treated with edetate... -
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- Overexpression of the Fanconi Anemia A Gene in Hela and MCF10A Cells
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Park WH
- KMID: 2252321
- Korean J Hematol.
- 2006 Mar;41(1):1-7.
- doi: 10.5045/kjh.2006.41.1.1
BACKGROUND: Fanconi Anemia (FA) is an autosomal recessive inherited disease, which is characterized by developmental abnormalities, progressive bone marrow failure and a predisposition to cancer. The phenotypes of FA cells... -
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- Retroviral-mediated IL-12 gene therapy for advanced murine tumors
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Kim SH, An CS, Tahara H, Park CH, Lotze MT, Robbins PD, Kim SY
- KMID: 2128626
- Exp Mol Med.
- 1997 Mar;29(1):53-58.
Interleukin 12 (IL-12), a heterodimeric cytokine, promotes an effective antitumor response against tumors of various histological types when delivered systemically as a protein or locally by gene transfer. We investigated... -
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- Effect of GCV on Neuroblastoma Cell Line Expressed by HSV-TK Gene with Retroviral Vector
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Cho HS, Lyu CJ, Kim YS, Kim TS, Kim BS
- KMID: 2335304
- J Korean Pediatr Soc.
- 1997 Dec;40(12):1719-1724.
Background : Gene transfer with vectors derived from murine retroviruses is restricted to cells which are proliferating and synthesizing DNA at the time of infection. Accordingly, selective introduction of genes... -
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- Effect of Retrovirus Mediated TNF-α Gene Transfer to Tumor Necrosis Factor(TNF) Sensitive Tumor Cell Lines on Sensitivity to TNF
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Oh YM, Park KY, Jung MP, Yoo CG, Kim YW, Han SG, Sim YS, Han YC
- KMID: 2160338
- Tuberc Respir Dis.
- 1994 Apr;41(2):87-96.
- doi: 10.4046/trd.1994.41.2.87
BACKGROUND: Since tumor necrosis factor was discovered in 1975, TNF has been well known about its cytotoxic effect on tumor cells in vivo and in vitro. According to the recent... -
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- Molecular Cloning of PERV-A and PERV-B Envelope Genes from Miniature Pigs
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Lee D, Lee J, Kwon M, Park HY, Kim YB
- KMID: 1579131
- J Bacteriol Virol.
- 2004 Dec;34(4):373-380.
Xenotransplantation of porcine organs has the potential to overcome the acute shortage of human tissues and organs for human transplantation. Swine represents an ideal source of such organs owing to... -
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- IL-2/HSVtk Gene Expression in Neuroblastoma Cell Line
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Koo JM, Moon YB, Cho HS, Park CY
- KMID: 2037438
- Korean J Pediatr Hematol Oncol.
- 2000 Oct;7(2):256-261.
PURPOSE: We investigated the efficacy of in vitro transduction of neuro 2a cells with interleukin-2 (IL-2) and herpes simplex virus-thymidine kinase (HSVtk) gene followed by assay of IL-2 and... -
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- Production of Recombinant Retroviruses Encoding Human Flt3 Ligand and IL-6 and Establishment of Genetically Modified OP9 Mouse Stromal Cells
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Kang HB, Kim YE, Kang HJ, Lee AR, Seok DE, Lee Y
- KMID: 1513550
- J Bacteriol Virol.
- 2007 Mar;37(1):31-38.
- doi: 10.4167/jbv.2007.37.1.31
Flt3 Ligand (FL) and IL-6 are multifunctional cytokines implicated in normal hematopoiesis and ex vivo expansion of hematopoietic stem cells. Retroviral vectors are useful for stable expression of genes in... -
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- Bystander-Mediated Regression of Murine Neuroblastoma via Retroviral Transfer of the HSV-TK Gene
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Cho HS, Lee HR, Kim MK
- KMID: 1785703
- J Korean Med Sci.
- 2004 Feb;19(1):107-112.
- doi: 10.3346/jkms.2004.19.1.107
Selective introduction of genes conferring chemosensitivity into proliferating tumor cells may be used to treat cancer. We investigated the bystander effect of retrovirusmediated gene transfer of herpes simplex virus thymidine... -
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