- Development of Actinobacillus pleuropneumoniae ApxI, ApxII, and ApxIII-specific ELISA methods for evaluation of vaccine efficiency
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Jung M, Won H, Shin MK, Oh MW, Shim S, Yoon I, Yoo HS
- KMID: 2454005
- J Vet Sci.
- 2019 Mar;20(2):e2.
- doi: 10.4142/jvs.2019.20.e2
Among various vaccines against Actinobacillus pleuropneumoniae, subunit vaccines using recombinant proteins of ApxI, ApxII, and ApxIII as vaccine antigens have shown good efficacy in terms of safety and protection. Therefore,... -
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- L1 Recombinant Proteins of HPV Tested for Antibody Forming Using Sera of HPV Quadrivalent Vaccine
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Akuzum B, Kim S, Nguyen TT, Hong J, Lee S, Kim E, Kim J, Choi Y, Jhun H, Lee Y, Kim H, Sohn DH, Kim S
- KMID: 2414555
- Immune Netw.
- 2018 Jun;18(3):e19.
- doi: 10.4110/in.2018.18.e19
Virus-like particles (VLPs) derived from human papillomavirus (HPV) L1 capsid proteins were used for HPV quadrivalent recombinant vaccine. The HPV quadrivalent vaccine is administrated in a 3-dose regimen of initial... -
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- Novel strategies in immunotherapy for allergic diseases
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Rajakulendran M, Tham EH, Soh JY, Van Bever
- KMID: 2410222
- Asia Pac Allergy.
- 2018 Apr;8(2):e14.
- doi: 10.5415/apallergy.2018.8.e14
Conventional immunotherapy (IT) for optimal control of respiratory and food allergies has been fraught with concerns of efficacy, safety, and tolerability. The development of adjuvants to conventional IT has potentially... -
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- Recombinant Activated Factor VII as a Second Line Treatment for Postpartum Hemorrhage
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Park SC, Yeom SR, Han SK, Jo YM, Kim HB
- KMID: 2405119
- Korean J Crit Care Med.
- 2017 Nov;32(4):333-339.
- doi: 10.4266/kjccm.2016.00787
BACKGROUND: Severe or massive postpartum hemorrhage (PPH) has remained a leading cause of maternal mortality for decades across the world and it results in critical obstetric complications. Recombinant activated factor... -
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- Simeprevir-Based Triple Therapy with Reduced Doses of Pegylated Interferon α-2a Plus Ribavirin for Interferon Ineligible Patients with Genotype 1b Hepatitis C Virus
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Tamai H, Ida Y, Kawashima , Shingaki N, Shimizu R, Moribata K, Nasu T, Maekita T, Iguchi M, Kato J, Nakao T, Kitano M
- KMID: 2412236
- Gut Liver.
- 2017 Jul;11(4):551-558.
- doi: 10.5009/gnl16525
BACKGROUND/AIMS: The present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such... -
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- Production of Recombinant Anti-Cancer Vaccines in Plants
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Lee JH, Ko K
- KMID: 2386899
- Biomol Ther.
- 2017 Jul;25(4):345-353.
- doi: 10.4062/biomolther.2016.126
Plant expression systems have been developed to produce anti-cancer vaccines. Plants have several advantages as bioreactors for the production of subunit vaccines: they are considered safe, and may be used... -
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- Immunogenicity of recombinant Lactobacillus plantarum NC8 expressing goose parvovirus VP2 gene in BALB/c mice
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Liu YY, Yang WT, Shi SH, Li YJ, Zhao L, Shi CW, Zhou FY, Jiang YL, Hu JT, Gu W, Yang GL, Wang CF
- KMID: 2412568
- J Vet Sci.
- 2017 Jun;18(2):159-167.
- doi: 10.4142/jvs.2017.18.2.159
Goose parvovirus (GPV) continues to be a threat to goose farms and has significant economic effects on the production of geese. Current commercially available vaccines only rarely prevent GPV infection.... -
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- Clinical Utility of a New Automated Hepatitis C Virus Core Antigen Assay for Prediction of Treatment Response in Patients with Chronic Hepatitis C
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Kim MN, Kim HS, Kim JK, Kim BK, Kim SU, Park JY, Kim DY, Ahn SH, Han KH
- KMID: 2468276
- J Korean Med Sci.
- 2016 Sep;31(9):1431-1437.
- doi: 10.3346/jkms.2016.31.9.1431
Hepatitis C virus core antigen (HCV Ag) is a recently developed marker of hepatitis C virus (HCV) infection. We investigated the clinical utility of the new HCV Ag assay for... -
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- Treatment Response and Long-Term Outcome of Peginterferon α and Ribavirin Therapy in Korean Patients with Chronic Hepatitis C
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Jung CH, Um SH, Kim TH, Yim SY, Suh SJ, Yim HJ, Seo YS, Choi HS, Chun HJ
- KMID: 2412080
- Gut Liver.
- 2016 Sep;10(5):808-817.
- doi: 10.5009/gnl15360
BACKGROUND/AIMS: Peginterferon plus ribavirin remains a standard therapy for patients with chronic hepatitis C (CHC) in Korea. We investigated the efficacy and long-term outcome of peginterferon and ribavirin therapy in... -
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- Regression of esophageal varices and splenomegaly in two patients with hepatitis-C-related liver cirrhosis after interferon and ribavirin combination therapy
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Lee SJ, Cho YK, Na SY, Choi EK, Boo SJ, Jeong SU, Song HJ, Kim HU, Kim BS, Song BC
- KMID: 2373140
- Clin Mol Hepatol.
- 2016 Sep;22(3):390-395.
- doi: 10.3350/cmh.2015.0050
Some recent studies have found regression of liver cirrhosis after antiviral therapy in patients with hepatitis C virus (HCV)-related liver cirrhosis, but there have been no reports of complete regression... -
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- Low-Dose Pegylated Interferon α-2b Plus Ribavirin for Elderly and/or Cirrhotic Patients with Genotype 2 Hepatitis C Virus
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Tamai H, Shingaki N, Mori Y, Moribata K, Kawashima , Maeda Y, Niwa T, Deguchi H, Inoue I, Maekita T, Iguchi M, Kato J, Ichinose M
- KMID: 2412052
- Gut Liver.
- 2016 Jul;10(4):617-623.
- doi: 10.5009/gnl15193
BACKGROUND/AIMS: This study aimed to predict sustained viral response (SVR) to low-dose pegylated interferon (PEG-IFN) plus ribavirin of elderly and/or cirrhotic patients with genotype 2 hepatitis C virus (HCV) using... -
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- Potential Efficacy of Pegylated Interferon-α and a Nucleos(t)ide Analogue as Combination Therapy for HBeAg-Positive Chronic Hepatitis B
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Wi CI, Kim WR, Gross JB, Stadheim L, Poterucha
- KMID: 2412051
- Gut Liver.
- 2016 Jul;10(4):611-616.
- doi: 10.5009/gnl14256
BACKGROUND/AIMS: Despite the potent suppression of the hepatitis B virus with modern antiviral agents, only a minority of HBeAg-positive patients achieve hepatitis B e antigen seroconversion. We aimed to explore... -
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- Combination of Pegylated Interferon and Nucleos(t)ide Therapy: Toward a Cure of Hepatitis B Virus Infection?
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Cho EJ, Lee JH, Yoon JH
- KMID: 2412034
- Gut Liver.
- 2016 Jul;10(4):497-498.
- doi: 10.5009/gnl15307
No abstract available. -
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- Improved development of somatic cell cloned bovine embryos by a mammary gland epithelia cells in vitro model
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He XY, Ma LB, He XN, Si WT, Zheng YM
- KMID: 2413163
- J Vet Sci.
- 2016 Jun;17(2):145-152.
- doi: 10.4142/jvs.2016.17.2.145
Previous studies have established a bovine mammary gland epithelia cells in vitro model by the adenovirus-mediated telomerase (hTERT-bMGEs). The present study was conducted to confirm whether hTERT-bMGEs were effective target... -
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- Association of IL28B Genotypes and Baseline Serum Interferon-γ-Inducible-Protein-10 Levels with Treatment Response in Hepatitis C Virus Patients in China
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Zhang R, Shao C, Huo N, Li M, Xu X
- KMID: 2411973
- Gut Liver.
- 2016 May;10(3):446-455.
- doi: 10.5009/gnl15162
BACKGROUND/AIMS: Several studies have demonstrated that serum interferon-γ-inducible-protein-10 (IP-10) levels at baseline and single nucleotide polymorphisms (SNPs) near the IL28B gene were associated with viral response and treatment outcomes. Our... -
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- Predicting Liver-Related Events Using Transient Elastography in Chronic Hepatitis C Patients with Sustained Virological Response
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Lee HW, Chon YE, Kim SU, Kim BK, Park JY, Kim DY, Ahn SH, Jung KS, Park YN, Han KH
- KMID: 2411971
- Gut Liver.
- 2016 May;10(3):429-436.
- doi: 10.5009/gnl15021
BACKGROUND/AIMS: Few studies have investigated prognostic factors for the development of liver-related events (LREs) in patients with chronic hepatitis C (CHC) who achieve sustained virological response (SVR). METHODS: We analyzed 190... -
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- Molecular cloning, purification and immunogenicity of recombinant Brucella abortus 544 malate dehydrogenase protein
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Reyes AW, Simborio H, Hop HT, Arayan LT, Kim S
- KMID: 2363344
- J Vet Sci.
- 2016 Mar;17(1):119-122.
- doi: 10.4142/jvs.2016.17.1.119
The Brucella mdh gene was successfully cloned and expressed in E. coli. The purified recombinant malate dehydrogenase protein (rMDH) was reactive to Brucella-positive bovine serum in the early stage, but... -
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- Acute pancreatitis associated with pegylated interferon-alpha-2a therapy in chronic hepatitis C
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Choi JW, Lee JS, Paik WH, Song TJ, Kim JW, Bae WK, Kim KA, Kim JG
- KMID: 2363035
- Clin Mol Hepatol.
- 2016 Mar;22(1):168-171.
- doi: 10.3350/cmh.2016.22.1.168
Chronic hepatitis C virus (HCV) infection is a major cause of liver cirrhosis and hepatocellular carcinoma. Combination therapy of pegylated interferon-alpha (PEG-IFN-α) and ribavirin (RBV) is a current standard treatment... -
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- A Novel Polyclonal Antiserum against Toxoplasma gondii Sodium Hydrogen Exchanger 1
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Xiao B, Kuang Z, Zhan Y, Chen D, Gao Y, Li M, Luo S, Hao W
- KMID: 2374013
- Korean J Parasitol.
- 2016 Feb;54(1):21-29.
- doi: 10.3347/kjp.2016.54.1.21
The sodium hydrogen exchanger 1 (NHE1), which functions in maintaining the ratio of Na+ and H+ ions, is widely distributed in cell plasma membranes. It plays a prominent role in... -
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- Allergenic Characterization of 27-kDa Glycoprotein, a Novel Heat Stable Allergen, from the Pupa of Silkworm, Bombyx mori
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Jeong KY, Son M, Lee JY, Park KH, Lee JH, Park JW
- KMID: 2359987
- J Korean Med Sci.
- 2016 Jan;31(1):18-24.
- doi: 10.3346/jkms.2016.31.1.18
Boiled silkworm pupa is a traditional food in Asia, and patients with silkworm pupa food allergy are common in these regions. Still now only one allergen from silkworm, arginine kinase,... -
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