- All-trans Retinoic Acid induced Myositis in a Patient with Acute Promyelocytic Leukemia
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Koh YS, Lee S, Kim YJ, Kim J, Hong SI, Park YH, Kim HJ, Kim DW, Lee JW, Min WS, Kim CC
- KMID: 2252407
- Korean J Hematol.
- 2003 Aug;38(3):191-194.
Acute promyelocytic leukemia (APL) is characterized by a specific chromosome translocation t(15;17), which fuses the promyelocytic leukemia (PML) gene to the retinoic acid receptor alpha (RARalpha) gene, and by a... -
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- Regulation of Sodium-iodine Symporter Expression by Retinoic Acid in Thyroid Cancer Cell Lines
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Chung KW, Song MS, Park JW, Clark OH, Noh DY, Oh SK, Choe KJ, Youn YK
- KMID: 2376119
- Korean J Endocr Surg.
- 2004 Jun;4(1):1-9.
- doi: 10.16956/kjes.2004.4.1.1
PURPOSE: Response to radioiodine therapy for thyroid cancer is related to the loss of sodium-iodine symporter protein caused by dedifferentiation of thyroid cancer cells. So we aimed to study mRNA... -
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- Combinational Treatment with Retinoic Acid Derivatives in Non-small Cell Lung Carcinoma In Vitro
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Choi EJ, Whang YM, Kim SJ, Kim HJ, Kim YH
- KMID: 1785789
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S52-S60.
- doi: 10.3346/jkms.2007.22.S.S52
The growth inhibitory effects of four retinoic acid (RA) derivatives, 9-cis RA, 13-cis RA, N-(4-hydroxyphenyl) retinamide (4-HPR), and all-trans retinoic acid (ATRA) were compared. In addition, the effects of various... -
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- Growth Regulation of Ovarian Cancer Cells through the Inactivation of AP-1 by Retinoid Derivatives
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Koh YM, Park JS, Namkoong S, Lee SY, Kim SA, Hong KJ, Um SJ
- KMID: 2329189
- J Korean Cancer Assoc.
- 2000 Dec;32(6):1043-1049.
PURPOSE: The growth regulatory effect of retinoid derivatives could be mediated by the transcriptional inactivation of AP-1 oncogenic transcription factor. By using ovarian cancer cell lines we were to investigate... -
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- Effect and Catabolism of All-trans Retinoic Acid in Head and Neck Squamous Cell Carcinoma
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Yoo SJ, Kwon HJ, Nam SY, Kim SY
- KMID: 1977700
- Korean J Otolaryngol-Head Neck Surg.
- 1999 Dec;42(12):1541-1546.
BACKGROUND AND OBJECTIVES: All-trans retinoic acid (RA) is a form of vitamin A analogue that has shown chemopreventive activities in many types of malignancy with the properties that regulate cellular... -
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- Retinoic Acid Enhances Drug-Induced Cell Death in Anticancer Drug-Resistant Cell Lines
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Whang YM, Kim YH, Shin SW, Kim BS, Kim JS, Yoo YD, Park SH
- KMID: 2134356
- Cancer Res Treat.
- 2002 Jun;34(3):212-217.
PURPOSE: Retinoids (RA), a group of vitamin A derivatives, is known to be important for regulation of normal cellular growth and differentiation. RA treatment of various cancers resulted in cell... -
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- Anticancer Effect and Apoptosis of All-trans-retinoic Acid on the Human Ovarian Epithelial Carcinoma Cell Lines
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Han JY, Jung WH, Kim TS
- KMID: 1725666
- Korean J Pathol.
- 2000 Mar;34(3):225-234.
Ovarian carcinoma is a serious disease in women. Some reports revealed all-trans-retinoic acid (tRA) inhibited the proliferation of ovarian carcinoma cell lines and induced apoptosis. The aim of this study... -
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- Developmental mRNA Expression of Cellular Retinoic Acid Binding Protein l and l in Rat
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Yoo Y, Kim HS, Son CS, Tockgo YC, Jeon YH
- KMID: 2335334
- J Korean Pediatr Soc.
- 1998 Feb;41(2):154-162.
PURPOSE: Retinoic acid (RA) is well known as a potent teratogenic agent in both deficiency and excess. Cellular retinoic acid binding proteins (CRABPs) are involved in RA. We carried this... -
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- The t (15;17) Breakpoint of the PML Gene in Acute Promyelocytic Leukemia
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Park SS, Cho HI
- KMID: 2146191
- Korean J Clin Pathol.
- 1997 Dec;17(6):885-897.
BACKGROUND: The characteristic t(15; 17) of acute promyelocytic leukemia (APL) fuses the retinoic acid receptor alpha (RARA) gene on chromosome 17 to the PML gene on chromosome 15. The test... -
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- Acetyl-CoA carboxylase beta expression mediated by MyoD and muscle regulatory factor 4 is differentially affected by retinoic acid receptor and retinoid X receptor
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Kim JY, Lee JJ, Kim KS
- KMID: 1088654
- Exp Mol Med.
- 2003 Feb;35(1):23-29.
Mammals have two major isoforms of acetyl-CoA carboxyase (ACC). The 275 kDa beta-form (ACC beta) is predominantly in heart and skeletal muscle while the 265 kDa alpha-form (ACC alpha) is... -
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- Acute Monocytic Leukemia with t(11;17)(q23;q21) Involving a Rearrangement of Mixed Lineage Leukemia Gene
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Kim KE, Kim SH, Han JY
- KMID: 2238845
- Korean J Lab Med.
- 2006 Oct;26(5):329-333.
- doi: 10.3343/kjlm.2006.26.5.329
A case of acute monocytic leukemia (AMoL) by French-American-British (FAB) classification in a 63-year-old male showed the abnormal karyotype 46,XY,t(11;17)(q23;q21), previously reported as a variant translocation in acute promyelocytic leukemia... -
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- Teratogenic Role of Selective Retinoids Receptor Agonists on the Growth of Peri-implantation and Early Post-implantation Stage Murine Embryos In Vitro
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Kang BM, Chae HD, Chu HS, Kang EH, Kim JH, Chang YS, Lee CB
- KMID: 2075816
- Korean J Obstet Gynecol.
- 1999 Jul;42(7):1442-1448.
OBJECTIVE: To identify the specific teratogenic role of retinoic acid receptor [RAR] alpha, beta and gamma-agonist, the growth of murine embryos that were exposed to the retinoids agonists was examined... -
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- A Case of Acute Promyelocytic Leukemia with 46, XX, del(5)(q23)/47, XX, del(5)(q23), +8 but Without (15;17) Translocation
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Oh SJ, Kim H, Ahn MJ, Kim IS, Jeong TJ, Choi IY, Chae JD, Lee WS, Cho YH, Lee YY
- KMID: 2083418
- Korean J Hematol.
- 2000 May;35(2):174-178.
Acute promyelocytic leukemia (APL/AML- M3) is a distinct subtype of acute myelogenous leukemia, which is characterized by unique morphologic, cytogenetic, molecular, and clinical features. In almost all APL patients, a... -
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- Promoter Methylation of CDKN2A, RARbeta, and RASSF1A in Non-Small Cell Lung Carcinoma: Quantitative Evaluation Using Pyrosequencing
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Lee JU, Sul HJ, Son JW
- KMID: 2050670
- Tuberc Respir Dis.
- 2012 Jul;73(1):11-21.
- doi: 10.4046/trd.2012.73.1.11
BACKGROUND: While qualitative analysis of methylation has been reviewed, the quantitative analysis of methylation has rarely been studied. We evaluated the methylation status of CDKN2A, RARbeta, and RASSF1A promoter regions... -
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- Retinoic Acid Receptor-beta Expression in Stage I Non-Small Cell Lung Cancer and Adjacent Normal Appearing Bronchial Epithelium
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Chang YS, Chung JH, Shin DH, Chung KY, Kim YS, Chang J, Kim SK, Kim SK
- KMID: 1734125
- Yonsei Med J.
- 2004 Jun;45(3):435-442.
- doi: 10.3349/ymj.2004.45.3.435
Retinoic acid receptor- (RAR-beta) is induced by and mediates the growth-inhibitory and apoptotic effects of retinoic acid (RA), suggesting that loss of RAR-betaexpression may be one of the critical events... -
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- Gene Promoter Hypermethylation in Tumors and Plasma of Breast Cancer Patients
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Bae YK, Shim YR, Choi JH, Kim MJ, Gabrielson E, Lee SJ, Hwang TY, Shin SO
- KMID: 1804577
- Cancer Res Treat.
- 2005 Aug;37(4):233-240.
PURPOSE: To measure the hypermethylation of four genes in primary tumors and paired plasma samples to determine the feasibility of gene promoter hypermethylation markers for detecting breast cancer in the... -
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- The Clinical Significance of Retinoic Acid Receptor beta Expressions in Primary and Recurred Metastatic Lymph Node Papillary Thyroid Carcinomas
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Han JP, Lee SJ, Choi KC, Park YE, Lee HR, Kang JG, Ryu OH, Kim CS, Lee BW, Hong EG, Kim HK, Kim DM, Yoo JM, Ihm SH, Yoo HJ, Choi MG
- KMID: 1958906
- J Korean Endocr Soc.
- 2007 Dec;22(6):419-427.
- doi: 10.3803/jkes.2007.22.6.419
BACKGROUND: The present study was designed to investigate the correlations of retinoic acid receptor beta(RARbeta) expression for primary and recurred metastatic lymph node (LN) papillary thyroid carcinoma (PTC) tissues and... -
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- Immunohistochemical Expression of Nuclear Retinoid Receptor and CREB(cAMP Response Element Binding Protein) in Lung Cancers
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Shin JW, Paik KH, Choi W, Park IW, Kim MK
- KMID: 2318749
- Tuberc Respir Dis.
- 2005 Dec;59(6):631-637.
BACKGROUND: Transcriptional factors of the CREB(cAMP Response Element Binding Protein) are involved in the regulation of gene expression in response to a variety of signaling pathways. Proteins produced by the... -
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- Correlation between Aberrant Promoter Hypermethylation of CpG Islands and the Clinical Outcome of Non-small Cell Lung Cancer after Curative Resection
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Lee SH, Kim YT, Sung SW, Kim JH
- KMID: 2005744
- J Lung Cancer.
- 2004 Dec;3(2):77-85.
PURPOSE: Aberrant methylation of CpG islands has been suggested as one of the cause for development of cancer by forcing specific tumor suppressor gene function. The methylation status of primary... -
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- Diagnosis of Malignant Pleural Effusion by using Aberrant Methylation of p16 and RARB2
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Rha SH, Lee SM, Koo TH, Shin BC, Huh JH, Um SJ, Yang DK, Lee SK, Son C, Roh MS, Bae HJ, Kim KN, Lee KN, Choi PJ
- KMID: 1970179
- Tuberc Respir Dis.
- 2008 Apr;64(4):285-292.
- doi: 10.4046/trd.2008.64.4.285
BACKGROUND: A diagnosis of malignant pleural effusion is clinically important, as the prognosis of lung cancer patients with malignant pleural effusion is poor. The diagnosis will be difficult if a... -
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