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Administration of Alpha(s1)-Casein Hydrolysate Increases Sleep and Modulates GABA(A) Receptor Subunit Expression

Yayeh T, Leem YH, Kim KM, Jung JC, Schwarz J, Oh KW, Oh S

Sleep is the most basic and essential physiological requirement for mental health, and sleep disorders pose potential risks of metabolic and neurodegenerative diseases. Tryptic hydrolysate of α(S1)-casein (α(S1)-CH) has been...
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Assessment of Switching to Suvorexant versus the Use of Add-on Suvorexant in Combination with Benzodiazepine Receptor Agonists in Insomnia Patients: A Retrospective Study

Hatano M, Kamei H, Inagaki R, Matsuzaki , Hanya M, Yamada S, Iwata N

OBJECTIVE: Suvorexant is a novel hypnotic drug that does not interact with the conventional γ-aminobutyric acid (GABA)-A receptor. We investigated the method by which suvorexant was introduced in insomnia patients...
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Expression Levels of GABA-A Receptor Subunit Alpha 3, Gabra3 and Lipoprotein Lipase, Lpl Are Associated with the Susceptibility to Acetaminophen-Induced Hepatotoxicity

Kim M, Yun JW, Shin K, Cho Y, Yang M, Nam KT, Lim KM

Drug-induced liver injury (DILI) is the serious and fatal drug-associated adverse effect, but its incidence is very low and individual variation in severity is substantial. Acetaminophen (APAP)-induced liver injury accounts...
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Association Study of Dopamine D2, D4 Receptor Gene, GABA(A) Receptor beta Subunit Gene, and Serotonin Transporter Gene Polymorphism with Children of Alcoholics in Korea: Preliminary Study

Cheon KA, Kim JW, Jun JY, Lee JY, Namkoong K

  • KMID: 2341260
  • J Korean Neuropsychiatr Assoc.
  • 2007 Jan;46(1):5-12.
OBJECTIVES: The studies on the genetic risk factors of the children of alcoholics (COAs) are still in an early stage. The A 1 allele of the dopamine receptor 2 gene...
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Glial Peripheral Benzodiazepine Receptor Mediates the Relief of Acute Stress-Induced Anxiety in Rats

Kim YU, Park HB, Lee JB, Kim JS, Cheung SD, Ha JH, Song CJ

  • KMID: 2340325
  • J Korean Neuropsychiatr Assoc.
  • 1999 May;38(3):647-655.
OBJECTIVES: Peripheral benzodiazepine receptor has been suggested to be associated with the relief of anxiety response induced by stresses. This study was designed to observe the anxiolytic activity of...
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Effects of Repeated Immobilization Stress on the Renal Peripheral Benzodiazepine Receptor in Rats

Park YH, Moon HK, Shin SM, Lee EJ, Lee ES, Ha JH

  • KMID: 1543943
  • J Korean Soc Pediatr Nephrol.
  • 1999 May;3(1):20-26.
Primary small cell carcinoma of the salivary gland is a rare neoplasm that accounts for approximately 1.8% of all primary major salivary gland malignancies. Because of its rarity, it is...
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Synthesis and Biodistribution of Flumazenil Derivative [F-18](3-(2-Fluoro) flumazenil for Imaging Benzodiazepine Receptor

Hong SH, Jeong JM, Chang YS, Lee DS, Chung JK, Cho JH, Lee SJ, Kang SS, Lee MC

  • KMID: 2038081
  • Korean J Nucl Med.
  • 1999 Dec;33(6):527-536.
PURPOSE: Radiotracers that bind to the central benzodiazepine receptor are useful for the investigation of various neurological and psychiatric diseases. [C-11]Flumazenil, a benzodiazepine antagonist, is the most widely used radioligand...
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Involvement of peripheral benzodiazepine receptor on contractility of canine trachealis muscle

Rhyu HY, Choi HC, Choi EM, Sohn UD, Lee KY, Kim WJ, Ha JH

  • KMID: 2285195
  • Korean J Physiol Pharmacol.
  • 1997 Dec;1(6):769-774.
Non-neuronal high affinity binding sites for benzodiazepines have been found in many peripheral tissues including cardiac muscle and vascular smooth muscle, and have been designated as 'peripheral benzodiazepine receptor'. Benzodiazepines have been shown...
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Changes of renal peripheral benzodiazepine receptor in the stress/anxiety response

Ha JH, Lee KH, Cheung SD, Park HB, Lee MG, Choi HC, Sohn UD, Lee KY, Kim WJ

  • KMID: 1554762
  • Korean J Physiol Pharmacol.
  • 1997 Oct;1(5):523-528.
Peripheral benzodiazepine receptor(PBR) has been identified in various peripheral tissues including kidney. The physiological and pharmacological functions of PBR are still uncertain, although it has been suggested that these are associated with the...
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GABA, benzodiazepine receptors and their functions

Chung YC, Han GS

  • KMID: 1691895
  • J Korean Neuropsychiatr Assoc.
  • 1991 May;30(3):431-450.
No abstract available.
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