- Association between the Alleles of the Dopamine D, Receptor and Schizophrenia
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Kim JI, Lee MS, Kwak DI
- KMID: 2202983
- J Korean Soc Biol Psychiatry.
- 1997 Nov;4(2):218-224.
The results regarding an association between the polymorphism sites in the dopamine D1 receptor gene and schizophrenia compelled us to study the distribution of the polymorphism in Korean schizophrenia and... -
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- The Association between the Dopamine D1 Receptor Genotype and Treatment Response in Korean Schizophrenic Patients
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Paik JW, Lee MS, Rhee CS, Lim DJ, Ham WH
- KMID: 2142165
- J Korean Soc Biol Psychiatry.
- 2001 Jun;8(1):106-110.
BACKGROUND: Dopamine receptors have been regarded as a strong candidate involved in etiology of schizophrenia and a target for various antipsychotic drugs. The purpose of our study was to investigate... -
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- Down-regulation of Dopamine D1 Receptor in Rat Penile Tissue after Cavernous Neurotomy
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Hyun JS, Jung HK, Bahk JY
- KMID: 2293321
- Korean J Urol.
- 2003 Aug;44(8):805-811.
PURPOSE: Dopamine plays a critical role in promoting sexual drive and penile erection through dopamine receptors. This study was performed to investigate whether the cavernousal nerve controls the expression of... -
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- Increased expression of dopamine receptors and transporter and hypomethylation of dopamine transporter gene in uterine leiomyoma
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Kim JH, Kim MJ, Choo YA, Choi YS, Lee TS, Kim HT
- KMID: 2128061
- Korean J Obstet Gynecol.
- 2005 Mar;48(3):628-637.
OBJECTIVE: Dopamine plays a key role in the proliferation regulation of the smooth muscle cells. The purpose of this study was to observe the degree of expression of dopamine D1... -
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- Interactions of Dopamine D1 and N-methyl-D-Aspartate Receptors are Required for Acute Cocaine-Evoked Nitric Oxide Efflux in the Dorsal Striatum
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Lee DK, Ahn SM, Shim YB, Koh WC, Shim I, Choe ES
- KMID: 2052824
- Exp Neurobiol.
- 2011 Jun;20(2):116-122.
- doi: 10.5607/en.2011.20.2.116
Alterations in nitric oxide (NO) release in response to psychostimulants in the striatum cause a plastic change contributing to the development and expression of addiction. In this study, regulation of... -
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- Role of Dopamine Receptors on Electroencephalographic Changes Produced by Repetitive Apomorphine Treatments in Rats
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Jang HS, Kim JY, Kim SH, Lee MG
- KMID: 2071664
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):147-151.
- doi: 10.4196/kjpp.2009.13.3.147
Repeated psychostimulants induce electroencephalographic (EEG) changes, which reflect adaptation of the neural substrate related to dopaminergic pathways. To study the role of dopamine receptors in EEG changes, we examined the... -
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- Role of Helix 8 in Dopamine Receptor Signaling
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Yang HS, Sun N, Zhao X, Kim HR, Park HJ, Kim KM, Chung KY
- KMID: 2462878
- Biomol Ther.
- 2019 Nov;27(6):514-521.
- doi: 10.4062/biomolther.2019.026
G protein-coupled receptors (GPCRs) are membrane receptors whose agonist-induced dynamic conformational changes trigger heterotrimeric G protein activation, followed by GRK-mediated phosphorylation and arrestin-mediated desensitization. Cytosolic regions of GPCRs have been... -
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- Distribution of the Dopamine D1 and D2 Receptor Protein Using Immunohistochemistry in Wistar-Kyoto Rat (WKY) and Spontaneously Hypertensive Rat (SHR) Kidneys
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Chang SH, Lee JD, Cho GJ, Koh PO, Choi WS, Chung SI
- KMID: 1990093
- Korean J Nephrol.
- 1998 Nov;17(6):841-852.
The kidney and balances of fluid and volume are the basic components of bloocl pressure control, and the kidney is the primary site that initiates the hypertensive process and is... -
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- Influence of SKF81297 on Catecholamine Release from the Perfused Rat Adrenal Medulla
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Choi DH, Cha JH, Lim DY
- KMID: 2285343
- Korean J Physiol Pharmacol.
- 2007 Oct;11(5):197-206.
The aim of the present study was to investigate the effects of 6-chloro-7,8-dihydroxy-1-phenyl-2,3, 4,5-tetrahydro-1H-3-benzazepine (SKF81297), a selective agonist of dopaminergic D1 receptor, on the secretion of catecholamines (CA) evoked by... -
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- Palmitoyl Serotonin Inhibits L-dopa-induced Abnormal Involuntary Movements in the Mouse Parkinson Model
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Park HY, Ryu YK, Go J, Son E, Kim KS, Kim MR
- KMID: 2349690
- Exp Neurobiol.
- 2016 Aug;25(4):174-184.
- doi: 10.5607/en.2016.25.4.174
L-3,4-dihydroxyphenylalanine (L-DOPA) is the most common treatment for patients with Parkinson's disease (PD). However, long term use of L-DOPA for PD therapy lead to abnormal involuntary movements (AIMs) known as... -
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- Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro
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Lim HC, Kim YG, Lim JH, Kim HS, Park H
- KMID: 724264
- Yonsei Med J.
- 2008 Jun;49(3):472-478.
- doi: 10.3349/ymj.2008.49.3.472
PURPOSE: Itopride hydrochloride (itopride) inhibits acetylcholinesterase (AChE) and antagonizes dopamine D(2) receptor, and has been used as a gastroprokinetic agent. However, its prokinetic effect on the small bowel or colon... -
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- Associations between DRDs and schizophrenia in a Korean population: multi-stage association analyses
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Lee KY, Joo EJ, Ji YI, Kim DH, Park J, Chung IW, Lee SI, Joo YH, Ahn YM, Song JY, Kim YS
- KMID: 991622
- Exp Mol Med.
- 2011 Jan;43(1):44-52.
- doi: 10.3858/emm.2011.43.1.005
The dysregulation of the dopaminergic system has been implicated in the pathophysiology of major psychosis, including schizophrenia, with dopamine receptor genes (DRDs) presently targeted as the most promising candidate genes.... -
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