- Association between Schizophrenia and the T102C Polymorphism of the 5-HT2A
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Lee MS, Nam JW, Kwak DI
- KMID: 2334570
- J Korean Soc Biol Psychiatry.
- 1998 Nov;5(2):215-218.
The 5-HT2A receptor is of great interest for research into schizophrenia and psychopharmacology in light of the observation that schizophrenic patients has 5-HT cortical-subcortical imbalance and atypical antipsychotic clozpine has... -
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- Past, Present and Future of Dopamine Hypothesis for Schizophrenia
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Chung YC, Li CR
- KMID: 2286977
- Korean J Psychopharmacol.
- 2004 Dec;15(4):393-400.
Many neurotransmitters other than dopamine, such as serotonin, glutamate, etc, have been implicated in the pathophysiology of schizophrenia. The atypicality of new antipsychotics has been attributed to the relatively more... -
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- Association between 5-HT2A Receptor Gene Promoter -1438A/G Polymorphism and Bipolar Disorder in a Korean Population
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Oh SY, Chee IS, Lee YH
- KMID: 2340525
- J Korean Neuropsychiatr Assoc.
- 2001 Jan;40(1):81-86.
OBJECTIVES: This study was designed to investigate the association between 5-HT 2A receptor gene promoter -1438A/G polymorphism and bipolar disorder in a Korean population. METHOD: 5-HT2A receptor gene promoter -1438A/G polymorphism... -
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- Blonanserin: New Serotonin-Dopamine Antagonist
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Kim W, Bahk WM
- KMID: 1856475
- Korean J Psychopharmacol.
- 2011 Jan;22(1):5-14.
Blonanserin is a newly developed agent which is approved for the treatment of schizophrenia in Japan and Korea. This agent has high affinity to dopamine D2 receptor and serotonin 5-HT2A... -
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- Association between Suicidal Attempts and Serotonin 2A Receptor Gene Polymorphism T102C in Korean
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Hahn SW
- KMID: 2287356
- Korean J Psychopharmacol.
- 2005 Jan;16(1):69-75.
OBJECTIVE: There are several lines of evidence suggested that a serotonergic dysfunction is involved in the susceptibility to suicide. Recently, the T102C polymorphism of the serotonin 2A receptor gene has... -
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- Tardive Dyskinesia: Treatment with Aripiprazole
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Kang NR, Kim MD
- KMID: 2171279
- Clin Psychopharmacol Neurosci.
- 2011 Apr;9(1):1-8.
Tardive dyskinesia is characterized by choreiform movements, or rhythmic abnormal involuntary movements of the face, mouth, tongue, trunk, and limbs. It is frequently associated with the use of neuroleptic medications.... -
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- No Association between 102T/C and 452His/Tyr Polymorphisms of 5-HT2A Receptor Gene and Schizophrenia in Korean Population
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Lee SK, Wang SK, Chee IS, Lee YH, Shin SC
- KMID: 2340270
- J Korean Neuropsychiatr Assoc.
- 1999 Jan;38(1):147-155.
OBJECTIVES: This study was designed to investigate the association between the silent mutation, 102T/C and the substitution of histidine by tyrosine at position 452, 452His/Tyr polymorphism of the 5HT2A... -
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- Outlook of Future Serotonergic Drugs and Their Clinical Usefulness: Focused on Schizophrenia and Depression
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Kim YK
- KMID: 2287362
- Korean J Psychopharmacol.
- 2006 May;17(3):273-282.
Serotonin has been implicated in the etiology and pathophysiology of mental illness such as depression, schizophrenia, anxiety disorder, eating disorder, obsessive compulsive disorder, and panic disorder. Many current used treatments... -
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- Association between Serotonin 2A(T102C) and 1B(G861C) Receptor Gene Polymorphism and Suicidal Attempt with Drug Intoxication in Korean Populations
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Kim DH, Kwon YJ, Kim JW, Shim SH, Jung HY
- KMID: 2248979
- Korean J Biol Psychiatry.
- 2004 Nov;11(2):110-116.
OBJECTIVES: Recently, polymorphisms of several serotonin genes have been suggested to be associated with suicide, but the results are still unclear. We examined whether the T102C polymorphisms of the serotonin... -
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- Association Study of a Serotonin Receptor 2A Gene -1438A/G Polymorphism and Anxiety-Related Traits
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Kim KH, Woo HY, Lim SW
- KMID: 2315806
- Psychiatry Investig.
- 2008 Dec;5(4):244-246.
OBJECTIVE: The aim of this study was to investigate the relationship between the -1438A/G polymorphism of serotonin receptor 2A (5HTR2A) and anxiety-related traits in Korean adolescent females. METHODS: A total of... -
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- Association between A-1438G Polymorphisms of 5-HT2A Receptor Promoter Gene and Tardive Dyskinesia
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Han SW, Shin JW, Choi TY, Kwon YJ, Jung HY, Han SH
- KMID: 2287334
- Korean J Psychopharmacol.
- 2003 Sep;14(3):244-251.
OBJECTIVE: Tardive dyskinesia (TD) is one of the serious side effects caused by long-term treatment with neuroleptic medication. Many investigators are trying to elucidate the pathophysiological mechanism of TD, and... -
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- Association between Tardive Dyskinesia and T103C Polymorphisms of 5-HT2A Receptor Gene
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Hahn SW, Shin JW, Choi TY, Woo SI, Jung HY, Jung HY, Han SH
- KMID: 2202783
- J Korean Soc Biol Psychiatry.
- 2003 Nov;10(2):133-140.
OBJECTIVE: Some candidate gene polymorphisms were reported to be associated with tardive dyskinesia (TD). The aim of this study was to investigate the association of the 5-HT2A receptor gene polymorphisms... -
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- -1438A/G Polymorphism of the 5-HT2A Receptor Gene in Korean and Han Chinese Patients with Schizophrenia
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Yi JH, Li GZ, Li SF, Wu LR, Chui YG, Cho AR, Chung JH, Chang HI
- KMID: 2341060
- J Korean Neuropsychiatr Assoc.
- 2005 Jan;44(1):25-31.
OBJECTIVES: The purpose of the present study was to investigate the association between -1438A/G polymorphism of 5-HT2A receptor gene and schizophrenia in Korean and Han Chinese population. METHODS: A sample of... -
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- Role of 5-HT2A Receptor Gene T102C Polymorphism in Coronary Artery Disease and Serum Lipid Level
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Choi JH, Zhang SY, Cho YS, Whang KK, Lee JH, Oh S, Chae IH, Zo JH, Kim HS, Oh BH, Lee MM, Choi YS, Park YB
- KMID: 2093863
- Korean Circ J.
- 2003 Apr;33(4):269-276.
- doi: 10.4070/kcj.2003.33.4.269
BACKGROUND AND OBJECTIVES: The 5-HT2A receptor is one of the main mediators of a serotonin-evoked coronary artery contraction. This is because vasoconstriction is selectively blocked by the 5-HT2 receptor antagonist,... -
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- Association Study between 5-HT2A Receptor and DRD3 Receptor Gene Polymorphism and Clinical Response to Atypical Antipsychotics in Patients with Schizophrenia
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Kim BS, Joo YH, Kim CY, Park JH, Song KY, Han OS
- KMID: 2340671
- J Korean Neuropsychiatr Assoc.
- 2002 May;41(3):409-420.
OBJECTIVES: This study was performed based on the hypothesis that the interindividual differences in clinical response to atypical antipsychotics might be associated with serotonin 2A receptor(5-HT2A) gene and(or) dopamine D3... -
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- A Case of Blonanserin-Induced Mania in Schizophrenia
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Park SY, Kim YK, Lee JH
- KMID: 1790747
- Korean J Schizophr Res.
- 2012 Jun;15(1):46-49.
- doi: 10.16946/kjsr.2012.15.1.46
Schizophrenia is a psychiatric disease which requires a long term treatment. Thus, patient's therapeutic compliance can be very crucial to the disease's prognosis. Moreover, the adverse effects of drugs are... -
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- Associations between Serotonergic Genes and Escitalopram Treatment Responses in Patients with Depressive Disorder and Acute Coronary Syndrome: The EsDEPACS Study
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Kang HJ, Bae KY, Kim SW, Shin IS, Hong YJ, Ahn Y, Jeong MH, Park SW, Kim YH, Yoon JS, Kim JM
- KMID: 2316609
- Psychiatry Investig.
- 2016 Jan;13(1):157-160.
- doi: 10.4306/pi.2016.13.1.157
Genes related to serotonin are associated with responses to treatment for depression. We examined associations between the serotonin transporter (5-HTT) and serotonin 2a receptor (5-HTR2a) genes and responses to treatment... -
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- Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase
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Sung DJ, Noh HJ, Kim JG, Park SW, Kim B, Cho H, Bae YM
- KMID: 2154286
- Exp Mol Med.
- 2013 Dec;45(12):e67.
Serotonin (5-hydroxytryptamine (5-HT)) is a neurotransmitter that regulates a variety of functions in the nervous, gastrointestinal and cardiovascular systems. Despite such importance, 5-HT signaling pathways are not entirely clear. We... -
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- Serotonin 2A Receptor Gene Polymorphism in Korean Children with Attention-Deficit/Hyperactivity Disorder
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Cho SC, Son JW, Kim BN, Kim JW, Yoo HJ, Hwang JW, Cho DY, Chung US, Park TW
- KMID: 2316195
- Psychiatry Investig.
- 2012 Sep;9(3):269-277.
OBJECTIVE: The purpose of this study was to investigate the association between the T102C polymorphism in the serotonin 2A receptor gene and attention-deficit/hyperactivity disorder (ADHD) in Korean patients. METHODS: A total... -
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- No Effect of Serotoninergic Gene Variants on Response to Interpersonal Counseling and Antidepressants in Major Depression
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Serretti A, Fabbri C, Pellegrini S, Porcelli S, Politi P, Bellino S, Menchetti , Mariotti V, Demi C, Martinelli V, Cappucciati M, Bozzatello P, Brignolo E, Brambilla , Pae CU, Balestrieri M, De Ronchi
- KMID: 2316266
- Psychiatry Investig.
- 2013 Jun;10(2):180-189.
OBJECTIVE: Gene variants within the serotonin pathway have been associated with major depressive disorder (MDD) treatment outcomes, however a possible different modulation on pharmacological or psychological treatments has never been... -
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