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Melanocortin 4 Receptor and Dopamine D2 Receptor Expression in Brain Areas Involved in Food Intake

Yoon YR, Baik JH

BACKGROUND: The melanocortin 4 receptor (MC4R) is involved in the regulation of homeostatic energy balance by the hypothalamus. Recent reports showed that MC4R can also control the motivation for food...
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A Case of Obese Patient Associated with Melanocortin 4 Receptor (MC4R) Mutation

Eun HS, Kim DH, Lee JS

  • KMID: 1838800
  • J Korean Soc Pediatr Endocrinol.
  • 2005 Dec;10(2):225-228.
There is now widespread recognition that the continuing increase in the prevalence of obesity seen in many countries is likely to have major adverse effects on public health. And genetic...
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Polymorphism of Melanocortin-4 Receptor and Obesity

Kim HS, Lee IK, Suh YS

  • KMID: 2063401
  • J Korean Diabetes Assoc.
  • 2003 Apr;27(2):123-131.
BACKGROUND: The application of genetics to obesity has made remarkable progress in recent years. The melanocortin-4 receptor (MC4R) regulates food intake, and possibly that of energy expenditure. The MC4R gene...
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The effect of melanocortin (Mc3 and Mc4) antagonists on serotonin-induced food and water intake of broiler cockerels

Zendehdel , Hamidi F, Babapour V, Mokhtarpouriani K, Fard RM

The current study was designed to examine the effects of intracerebroventricular injections of SHU9119 [a nonselective melanocortin receptor (McR) antagonist] and MCL0020 (a selective McR antagonist) on the serotonin-induced eating...
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Lack of Replication of Genetic Association with Body Mass Index Detected by Genome-wide Association Study

Lee HI, Kim JJ, Park T, Kim K, Lee JE, Cho YS, Lee JY, Han BG, Lee JK

  • KMID: 2053263
  • Genomics Inform.
  • 2011 Jun;9(2):59-63.
Obesity provokes many serious human diseases, including various cardiovascular diseases and diabetes. Body mass index (BMI) is a highly heritable trait that is broadly used to diagnose obesity. To identify...
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A Case of Pseudopseudohypoparathyroidism with Normal Stature

Kim SR, Doh YJ, Kim HK, Moon SS, Lee JY, Jeon JH, Kim SW, Kim BW, Lee IK, Kim JG

Pseudopseudohypoparathyroidism (PPHP) is characterized by the phenotype of Albright hereditary osteodystrophy (AHO) alone without biochemical evidence of multihormone resistance, which is unlike pseudohypoparathyroidism. AHO is associated with characteristic developmental abnormalities...
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