- Reirradiation of head and neck cancer in the era of intensity-modulated radiotherapy: patient selection, practical aspects, and current evidence
-
Kim YS
- KMID: 2401794
- Radiat Oncol J.
- 2017 Mar;35(1):1-15.
- doi: 10.3857/roj.2017.00122
Locoregional failure is the most frequent pattern of failure in locally advanced head and neck cancer patients and it leads to death in most of the patients. Second primary tumors... -
- CITED
-
- Close
- SHARE
-
- Close
- Brain metastasis in human epidermal growth factor receptor 2-positive breast cancer: from biology to treatment
-
Koo T, Kim IA
- KMID: 2316750
- Radiat Oncol J.
- 2016 Mar;34(1):1-9.
- doi: 10.3857/roj.2016.34.1.1
Overexpression of human epidermal growth factor receptor 2 (HER2) is found in about 20% of breast cancer patients. With treatment using trastuzumab, an anti-HER2 monoclonal antibody, systemic control is improved.... -
- CITED
-
- Close
- SHARE
-
- Close
- Caffeic Acid Phenethyl Ester Increases Radiosensitivity of Estrogen Receptor-Positive and -Negative Breast Cancer Cells by Prolonging Radiation-Induced DNA Damage
-
Khoram NM, Bigdeli B, Nikoofar A, Goliaei B
- KMID: 2176317
- J Breast Cancer.
- 2016 Mar;19(1):18-25.
- doi: 10.4048/jbc.2016.19.1.18
PURPOSE: Breast cancer is an important cause of death among women. The development of radioresistance in breast cancer leads to recurrence after radiotherapy. Caffeic acid phenethyl ester (CAPE), a polyphenolic... -
- CITED
-
- Close
- SHARE
-
- Close
- Tumor Growth Suppression and Enhanced Radioresponse by an Exogenous Epidermal Growth Factor in Mouse Xenograft Models with A431 Cells
-
Lim YJ, Jeon SR, Koh JM, Wu HG
- KMID: 2403413
- Cancer Res Treat.
- 2015 Oct;47(4):921-930.
- doi: 10.4143/crt.2014.153
PURPOSE: The purpose of this study was to evaluate whether an exogenous epidermal growth factor (EGF) could induce anti-tumor and radiosensitizing effects in vivo. MATERIALS AND METHODS: BALB/c-nu mice that were... -
- CITED
-
- Close
- SHARE
-
- Close
- In Vitro and In Vivo Radiosensitizing Effect of Valproic Acid on Fractionated Irradiation
-
Chie EK, Shin JH, Kim JH, Kim HJ, Kim IA, Kim IH
- KMID: 2148504
- Cancer Res Treat.
- 2015 Jul;47(3):527-533.
- doi: 10.4143/crt.2014.026
PURPOSE: This study was conducted in order to validate the radiosensitization effect of valproic acid, a biologically available histone deacetylase inhibitor, for fractionated radiation. MATERIALS AND METHODS: Radiosensitization effect of valproic... -
- CITED
-
- Close
- SHARE
-
- Close
- Sequence-Dependent Radiosensitization of Histone Deacetylase Inhibitors Trichostatin A and SK-7041
-
Kim JH, Kim IH, Shin JH, Kim HJ, Kim IA
- KMID: 2167644
- Cancer Res Treat.
- 2013 Dec;45(4):334-342.
PURPOSE: This preclinical study is to determine whether the capacity of histone deacetylase (HDAC) inhibitors to enhance radiation response depends on temporal sequences of HDAC inhibition and irradiation. MATERIALS AND METHODS:... -
- CITED
-
- Close
- SHARE
-
- Close
- In Vitro Radiosensitization of Flavopiridol Did Not Translated into In Vivo Radiosensitization
-
Kim S
- KMID: 1443610
- J Korean Soc Ther Radiol Oncol.
- 2011 Jun;29(2):83-90.
- doi: 10.3857/jkstro.2011.29.2.83
PURPOSE: Flavopiridol enhanced radiation-induced apoptosis of cancer cells in our previous in vitro study. The purpose of this study was to assess if flavopiridol could enhance the radioresponse of mouse... -
- CITED
-
- Close
- SHARE
-
- Close
- Phenylpropanoids in radioregulation: double edged sword
-
Kim W, Seong KM, Youn B
- KMID: 1107373
- Exp Mol Med.
- 2011 Jun;43(6):323-333.
- doi: 10.3858/emm.2011.43.6.034
Radiotherapy, frequently used for treatment of solid tumors, carries two main obstacles including acquired radioresistance in cancer cells during radiotherapy and normal tissue injury. Phenylpropanoids, which are naturally occurring phytochemicals... -
- CITED
-
- Close
- SHARE
-
- Close
- In vivo Radiosensitization Effect of HDAC Inhibitor, SK-7041 on RIF-1 Cell Line
-
Chie EK, Shin JH, Kim IA, Kim IH
- KMID: 1460139
- J Korean Soc Ther Radiol Oncol.
- 2010 Dec;28(4):219-223.
- doi: 10.3857/jkstro.2010.28.4.219
PURPOSE: To test the radiosensitizing effect of the newly synthesized novel histone deacetylase inhibitor, SK-7041 in vivo. MATERIALS AND METHODS: The RIF-1 cell line was implanted into the back of a... -
- CITED
-
- Close
- SHARE
-
- Close
- In Vitro Enhancement of Radiosensitivity by the Combination of Celecoxib and Ad-mda7 in Human Breast Cancer Cells
-
Kang SG, Suh YJ
- KMID: 2425146
- J Breast Cancer.
- 2010 Sep;13(3):275-285.
PURPOSE: Celecoxib and Ad-mda7 have shown its ability to enhance radiosensitivity in various cancer cells in vitro. We expected to synergistically enhance radiosensitivity by combing celecoxib and Ad-mda7 in breast... -
- CITED
-
- Close
- SHARE
-
- Close
- Combination Effect of Nimotuzumab with Radiation in Colorectal Cancer Cells
-
Shin HK, Kim MS, Jeong JH
- KMID: 1460147
- J Korean Soc Ther Radiol Oncol.
- 2010 Sep;28(3):147-154.
- doi: 10.3857/jkstro.2010.28.3.147
PURPOSE: To investigate the radiosensitizing effect of the selective epidermal growth factor receptor (EGFR) inhibitor nimotuzumab in human colorectal cancer cell lines. MATERIALS AND METHODS: Four human colorectal cancer cell lines,... -
- CITED
-
- Close
- SHARE
-
- Close
- Concurrent Chemoradiotherapy with Weekly Paclitaxel for Locally Advanced Non-small Cell Lung Cancer
-
Jeong SH, Jung JH, Lee HW, Kang SY, Choi YW, Ahn MS, Hwang YH, Oh YT, Choi JH, Sheen SS, Park KJ
- KMID: 1464704
- J Lung Cancer.
- 2009 Jun;8(1):8-12.
- doi: 10.6058/jlc.2009.8.1.8
PURPOSE: Concurrent chemoradiotherapy (CCRT) is the standard treatment for locally advanced non-small cell lung cancer (NSCLC). Paclitaxel is an active agent against NSCLC and it has a radiosensitizing effect. We... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of Combination Therapy with Radiation and Selective Cyclooxygenase-2 Inhibitor on Xenografted Human Oral Cavity Squamous Cell Carcinoma in Nude Mice
-
Kim JH, Park SY, Kim HJ, Kim KB, Yang HS, Lee KS, Lee HJ, Ji YH
- KMID: 2276625
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Apr;49(4):420-425.
BACKGROUND AND OBJECTIVES: It is known that tumor cells over-expressing COX-2 have resistance to many anticancer treatments. Among those treatments, along with surgery and chemotherapy, radiation therapy plays a significant... -
- CITED
-
- Close
- SHARE
-
- Close
- Optimal Timing for the Administration of Capecitabine with Preoperative Chemoradiation for Locally Advanced Rectal Cancer
-
Noh YJ, Choi WS, Kim JH, Kim JC, Yu CS, Kim HC, Kim TW, Chang HM, Ryu MH, Ahn SD, Lee SW, Shin SS, Lee JE, Choi EK
- KMID: 2166090
- Cancer Res Treat.
- 2006 Feb;38(1):30-34.
PURPOSE: Capecitabine is an oral fluoropyrimidine carbamate and it is known as an effective radiosensitizer. Capecitabine and its metabolite reach their peak concentration in the plasma at 1~2 hours after... -
- CITED
-
- Close
- SHARE
-
- Close
- Enhancement of Radiation Effects by Flavopiridol in Uterine Cervix Cancer Cells
-
Kim S, Wu HG, Shin JH, Park HJ, Kim IA, Kim IH
- KMID: 2270838
- Cancer Res Treat.
- 2005 Jun;37(3):191-195.
PURPOSE: To determine the effects of combinations of radiation and flavopiridol, an inhibitor of cyclin-dependent kinases and global transcription, in a human uterine cervix cancer cell line. MATERIALS AND METHODS:... -
- CITED
-
- Close
- SHARE
-
- Close
- Leptomycin B Increases Radiosensitization by Trichostain A in HeLa Cells
-
Kim IA, Kim JH, Shin JH, Kim IH, Kim JS, Wu HG, Chie EK, Kim YH, Kim BK, Hong S, Ha SW, Park CI
- KMID: 2198566
- J Korean Soc Ther Radiol Oncol.
- 2005 Jun;23(2):116-122.
PURPOSE: Histone deacetylase inhibitors (HDIs) are emerging as potentially useful components of anticancer therapy and their radiosensitizing effects have become evident. Specific HDIs are now available that preferentially inhibit specific... -
- CITED
-
- Close
- SHARE
-
- Close
- A Histone Deacetylase Inhibitor, Trichostatin A, Enhances Radiosensitivity by Abrogating G2/M Arrest in Human Carcinoma Cells
-
Kim IA, Kim JH, Shin JH, Kim IH, Kim JS, Wu HG, Chie EK, Kim YH, Kim BK, Hong S, Park SW, Ha SW, Park CI
- KMID: 1571472
- Cancer Res Treat.
- 2005 Apr;37(2):122-128.
PURPOSE: Histone deacetylase inhibitors (HDIs) are emerging as potentially useful components in anticancer therapy. In this study, we tried to confirm the radiosensitizing effect of trichostatin A (TSA) on a... -
- CITED
-
- Close
- SHARE
-
- Close
- Prospective Phase II Study of Preoperative Chemoradiation with Capecitabine in Locally Advanced Rectal Cancer
-
Park JH, Kim JH, Ahn SD, Lee SW, Shin SS, Kim JC, Yu CS, Kim HC, Kang YK, Kim TW, Chang HM, Ryu MH, Choi EK
- KMID: 2166125
- Cancer Res Treat.
- 2004 Dec;36(6):354-359.
PURPOSE: Capecitabine is an attractive oral chemotherapeutic agent that has a radiosensitizing effect and tumor-selectivity. This study was performed to evaluate the efficacy and toxicity of preoperative chemoradiation therapy, when... -
- CITED
-
- Close
- SHARE
-
- Close
- Concurrent Chemoradiation with Weekly Paclitaxel in Locally Advanced Non-small Cell Lung Cancer
-
Bae KW, Song TH, Yang JY, Kim YS, Park JS, Jee YK, Lee KY
- KMID: 2318500
- Tuberc Respir Dis.
- 2004 Oct;57(4):351-357.
BACKGROUND: Paclitaxel is highly beneficial anticancer drug for the treatment of non-small cell lung cancer and has shown remarkable radiosensitizing effect in vitro. We evaluated whether concurrent chemoradiation therapy with... -
- CITED
-
- Close
- SHARE
-
- Close
- Enhancement of radiosensitivity by combined ceramide and dimethylsphingosine treatment in lung cancer cells
-
Park HW, Song JY, Kim KS, Han Y, Kim CW, Yi SY, Yun YS
- KMID: 1123762
- Exp Mol Med.
- 2004 Oct;36(5):411-419.
Ceramide generated from sphingomyelin in response to ionizing radiation has been implicated as a second messenger to induce cellular proapoptotic signals. Both ceramide and its metabolic inhibitor, N, N-dimethyl-D-erythro-sphingosine (DMS),... -
- CITED
-
- Close
- SHARE
-
- Close
