- An experimental study on effect of tourniquet ischemia and hyperthermia on irradiation
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Park JH, Han MC
- KMID: 2463414
- J Korean Radiol Soc.
- 1981 Jun;17(1):1-13.
- doi: 10.3348/jkrs.1981.17.1.1
To evaluate the influence of tourniquet ischemia and hyperthermia on the radiation effect of skin, theexperimental study was undertaken using a total of 344 mice. A single dose of irradiation... -
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- Sequence-Dependent Radiosensitization of Histone Deacetylase Inhibitors Trichostatin A and SK-7041
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Kim JH, Kim IH, Shin JH, Kim HJ, Kim IA
- KMID: 2167644
- Cancer Res Treat.
- 2013 Dec;45(4):334-342.
PURPOSE: This preclinical study is to determine whether the capacity of histone deacetylase (HDAC) inhibitors to enhance radiation response depends on temporal sequences of HDAC inhibition and irradiation. MATERIALS AND METHODS:... -
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- Enhancement of Radiation Effects by Flavopiridol in Uterine Cervix Cancer Cells
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Kim S, Wu HG, Shin JH, Park HJ, Kim IA, Kim IH
- KMID: 2270838
- Cancer Res Treat.
- 2005 Jun;37(3):191-195.
PURPOSE: To determine the effects of combinations of radiation and flavopiridol, an inhibitor of cyclin-dependent kinases and global transcription, in a human uterine cervix cancer cell line. MATERIALS AND METHODS:... -
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- In Vitro Radiosensitization of Flavopiridol Did Not Translated into In Vivo Radiosensitization
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Kim S
- KMID: 1443610
- J Korean Soc Ther Radiol Oncol.
- 2011 Jun;29(2):83-90.
- doi: 10.3857/jkstro.2011.29.2.83
PURPOSE: Flavopiridol enhanced radiation-induced apoptosis of cancer cells in our previous in vitro study. The purpose of this study was to assess if flavopiridol could enhance the radioresponse of mouse... -
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- Phenylpropanoids in radioregulation: double edged sword
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Kim W, Seong KM, Youn B
- KMID: 1107373
- Exp Mol Med.
- 2011 Jun;43(6):323-333.
- doi: 10.3858/emm.2011.43.6.034
Radiotherapy, frequently used for treatment of solid tumors, carries two main obstacles including acquired radioresistance in cancer cells during radiotherapy and normal tissue injury. Phenylpropanoids, which are naturally occurring phytochemicals... -
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- Combination Effect of Nimotuzumab with Radiation in Colorectal Cancer Cells
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Shin HK, Kim MS, Jeong JH
- KMID: 1460147
- J Korean Soc Ther Radiol Oncol.
- 2010 Sep;28(3):147-154.
- doi: 10.3857/jkstro.2010.28.3.147
PURPOSE: To investigate the radiosensitizing effect of the selective epidermal growth factor receptor (EGFR) inhibitor nimotuzumab in human colorectal cancer cell lines. MATERIALS AND METHODS: Four human colorectal cancer cell lines,... -
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- The Effect of Combination Therapy with Radiation and Selective Cyclooxygenase-2 Inhibitor on Xenografted Human Oral Cavity Squamous Cell Carcinoma in Nude Mice
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Kim JH, Park SY, Kim HJ, Kim KB, Yang HS, Lee KS, Lee HJ, Ji YH
- KMID: 2276625
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Apr;49(4):420-425.
BACKGROUND AND OBJECTIVES: It is known that tumor cells over-expressing COX-2 have resistance to many anticancer treatments. Among those treatments, along with surgery and chemotherapy, radiation therapy plays a significant... -
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- Caffeic Acid Phenethyl Ester Increases Radiosensitivity of Estrogen Receptor-Positive and -Negative Breast Cancer Cells by Prolonging Radiation-Induced DNA Damage
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Khoram NM, Bigdeli B, Nikoofar A, Goliaei B
- KMID: 2176317
- J Breast Cancer.
- 2016 Mar;19(1):18-25.
- doi: 10.4048/jbc.2016.19.1.18
PURPOSE: Breast cancer is an important cause of death among women. The development of radioresistance in breast cancer leads to recurrence after radiotherapy. Caffeic acid phenethyl ester (CAPE), a polyphenolic... -
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- Brain metastasis in human epidermal growth factor receptor 2-positive breast cancer: from biology to treatment
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Koo T, Kim IA
- KMID: 2316750
- Radiat Oncol J.
- 2016 Mar;34(1):1-9.
- doi: 10.3857/roj.2016.34.1.1
Overexpression of human epidermal growth factor receptor 2 (HER2) is found in about 20% of breast cancer patients. With treatment using trastuzumab, an anti-HER2 monoclonal antibody, systemic control is improved.... -
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- Reirradiation of head and neck cancer in the era of intensity-modulated radiotherapy: patient selection, practical aspects, and current evidence
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Kim YS
- KMID: 2401794
- Radiat Oncol J.
- 2017 Mar;35(1):1-15.
- doi: 10.3857/roj.2017.00122
Locoregional failure is the most frequent pattern of failure in locally advanced head and neck cancer patients and it leads to death in most of the patients. Second primary tumors... -
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- The Cytotoxic and Radiosensitizing Effects of Taxol in Uterine Sarcoma Cell Lines
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Lee HY, Park DC, Kim SW, Lew YO, Kim DH
- KMID: 2272001
- Korean J Obstet Gynecol.
- 2003 Apr;46(4):725-731.
OBJECTIVE: The cytotoxic and radiosensitizing effects of Taxol in uterine sarcoma cell lines were investigated. METHODS: Two uterine sarcoma cell lines with different Taxol responses were used, namely, Taxol- sensitive and... -
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- Tumor Growth Suppression and Enhanced Radioresponse by an Exogenous Epidermal Growth Factor in Mouse Xenograft Models with A431 Cells
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Lim YJ, Jeon SR, Koh JM, Wu HG
- KMID: 2403413
- Cancer Res Treat.
- 2015 Oct;47(4):921-930.
- doi: 10.4143/crt.2014.153
PURPOSE: The purpose of this study was to evaluate whether an exogenous epidermal growth factor (EGF) could induce anti-tumor and radiosensitizing effects in vivo. MATERIALS AND METHODS: BALB/c-nu mice that were... -
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- The effect of retinoic acid on radiosensitivity analyzed by linear-quadratic model and apoptosis in head and neck squamous carcinoma cell lines
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Lee ES, Kang BH, Heo MS, Lee SS, Choi HB, Choi SC, Park TW
- KMID: 1887550
- Korean J Oral Maxillofac Radiol.
- 2001 Sep;31(3):135-143.
PURPOSE: To evaluate the effect of all-trans-retinoic acid on radiosensitivity and radiation-induced apoptosis in NHOK, HEp-2 and FaDu cell lines. Material and Methods : We measured the changes in survival fraction... -
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- The Effect of Paclitaxel(Taxol) on the Radiation in the Rat Liver
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Lee KJ, Koo H
- KMID: 2170928
- Ewha Med J.
- 1997 Mar;20(1):101-109.
- doi: 10.12771/emj.1997.20.1.101
OBJECTIVES: Paclitaxel(Taxol) si a chemotherapeutic agent with potent microtubule stabilizing activities that arrests cell cycle in G2-M. Since D2-m is the most radiosensitive phase of the cell cycle, paclitaxel has... -
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- Leptomycin B Increases Radiosensitization by Trichostain A in HeLa Cells
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Kim IA, Kim JH, Shin JH, Kim IH, Kim JS, Wu HG, Chie EK, Kim YH, Kim BK, Hong S, Ha SW, Park CI
- KMID: 2198566
- J Korean Soc Ther Radiol Oncol.
- 2005 Jun;23(2):116-122.
PURPOSE: Histone deacetylase inhibitors (HDIs) are emerging as potentially useful components of anticancer therapy and their radiosensitizing effects have become evident. Specific HDIs are now available that preferentially inhibit specific... -
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- In Vitro and In Vivo Radiosensitizing Effect of Valproic Acid on Fractionated Irradiation
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Chie EK, Shin JH, Kim JH, Kim HJ, Kim IA, Kim IH
- KMID: 2148504
- Cancer Res Treat.
- 2015 Jul;47(3):527-533.
- doi: 10.4143/crt.2014.026
PURPOSE: This study was conducted in order to validate the radiosensitization effect of valproic acid, a biologically available histone deacetylase inhibitor, for fractionated radiation. MATERIALS AND METHODS: Radiosensitization effect of valproic... -
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- Chlorophyll derivatives (CpD) extracted from silk worm excreta are specifically cytotoxic to tumor cells in vitro
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Lee WY, Park JH, Kim BS, Han MJ, Hahn BS
- KMID: 1107340
- Yonsei Med J.
- 1990 Sep;31(3):225-233.
- doi: 10.3349/ymj.1990.31.3.225
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- Concurrent Chemoradiotherapy with Weekly Paclitaxel for Locally Advanced Non-small Cell Lung Cancer
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Jeong SH, Jung JH, Lee HW, Kang SY, Choi YW, Ahn MS, Hwang YH, Oh YT, Choi JH, Sheen SS, Park KJ
- KMID: 1464704
- J Lung Cancer.
- 2009 Jun;8(1):8-12.
- doi: 10.6058/jlc.2009.8.1.8
PURPOSE: Concurrent chemoradiotherapy (CCRT) is the standard treatment for locally advanced non-small cell lung cancer (NSCLC). Paclitaxel is an active agent against NSCLC and it has a radiosensitizing effect. We... -
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- Comparison of Postoperative Adjuvant Radiation therapy alone vs. Chemoradiotherapy in Adenocarcinoma of the Rectum
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Lim JJ, Park W, Seong J, Suh CO, Kim GE, Min JS, Chung HC, Roh JK, Kim BS
- KMID: 1569229
- J Korean Soc Ther Radiol Oncol.
- 1998 Mar;16(1):35-41.
PURPOSE: To investigate the role of adjuvant chemoradiotherapy in adenocarcinoma of the rectum, we retrospectively compared the treatment results between postoperative adjuvant radiotherapy alone and combined chemoradiotherapy. MATERIAL AND METHODS:... -
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- Trichostatin A, a Histone Deacetylase Inhibitor, Potentiated Cytotoxic Effect of Ionizing Radiation in Human Head and Neck Cancer Cell Lines
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Kim JH, Shin JH, Chie EK, Wu HG, Kim JS, Kim IH, Ha SW, Park CI, Kang WS
- KMID: 2323831
- J Korean Soc Ther Radiol Oncol.
- 2004 Jun;22(2):138-144.
PURPOSE: We have previously reported that human glioblastoma cells are sensitized to radiation-induced death after their exposure to trichostatin A (TSA), a histone deacetylase inhibitor (HDAC-I), prior to the... -
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