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The present and future of rabies vaccine in animals

Yang DK, Kim HH, Lee KW, Song JY

  • KMID: 2391971
  • Clin Exp Vaccine Res.
  • 2013 Jan;2(1):19-25.
An effective strategy for preventing rabies consists of controlling rabies in the host reservoir with vaccination. Rabies vaccine has proven to be the most effective weapon for coping with this...
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Antibody Response in Korean Raccoon Dogs Inoculated with Inactivated Rabies Vaccines

Yang DK, Go TO, Nam YH, Kim HH, Cho SD, Lee KW, Choi SS, Song JY

Since sylvatic rabies was first identified in South Korea in 1993, over three million bait vaccine doses have been distributed to rabies risk regions in order to block transmission of...
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Molecular Identification of the Vaccine Strain from the Inactivated Rabies Vaccine

Yang DK, Oh YI, Cho SD, Kang HK, Lee KW, Kim YH, Song JY

Since 1994, several different inactivated rabies vaccines have been used to immunize domestic animals such as dogs, cats, and cattle in South Korea. The Korean Veterinary Authority has conducted safety...
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A genetically modified rabies vaccine (ERAGS) induces protective immunity in dogs and cattle

Yang DK, Kim HH, Lee SH, Jeong WH, Tark D, Cho IS

PURPOSE: The current live attenuated rabies vaccine must be replaced with a safer vaccine based on the ERAGS strain to prevent rabies in South Korea. We evaluated the safety and...
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Antibody Response in Cattle and Guinea Pigs Inoculated with Rabies Vaccines

Yang DK, Jeong WH, Kim HH, Nah JJ, Kim JJ, Choi SS, Kim JT, Song JY

One hundred ninety-five rabies cases in cattle were identified in South Korea since 1993. As most of rabies cases have a relation to rabid Korean raccoon dogs (Nyctereutes procyonoides koreensis),...
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Immunogenicity and efficacy of a plasmid DNA rabies vaccine incorporating Myd88 as a genetic adjuvant

Ullas PT, Desai A, Madhusudana SN

PURPOSE: Myeloid differentiation factor 88 (Myd88), a ubiquitous Toll-like receptor adaptor molecule, has been reported to play important roles in B cell responses to infections and vaccination. The present study...
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Clinical analysis of rabies post-exposure prophylaxis for animal bite in emergency department

Kim DI, Yeo W, Park T, Kwon J

OBJECTIVE: This study examined patients who visited the emergency department of a national medical center equipped with rabies vaccine and rabies immunoglobulin to confirm whether the treatment for rabies vaccination...
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Cellular immune response following pre-exposure and postexposure rabies vaccination by intradermal and intramuscular routes

Venkataswamy MM, Madhusudana SN, Sanyal SS, Taj S, Belludi AY, Mani RS, Hazra N

PURPOSE: Immunization against rabies in humans induces protective neutralizing antibodies; however, the induction of type 1 or type 2 cytokine mediated cellular immune responses following rabies vaccination is not understood....
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Safety and immunogenicity of recombinant rabies virus (ERAGS) in mice and raccoon dogs

Yang DK, Kim HH, Choi SS, Kim JT, Lee KB, Lee SH, Cho IS

PURPOSE: The development of a genetically modified live rabies vaccine applicable to wild raccoon dogs is necessary for the eradication of rabies in Korea. Thus, we constructed a recombinant rabies...
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A single immunization with recombinant rabies virus (ERAG3G) confers complete protection against rabies in mice

Yang DK, Nakagawa K, Ito N, Kim HH, Hyun BH, Nah JJ, Sugiyama M, Song JY

PURPOSE: New alternative bait rabies vaccines applicable to pet dogs and wild animals are needed to eradicate rabies in Korea. In this study, recombinant rabies virus, ERAG3G strain was constructed...
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Immunization for International Travelers

Chung MH

  • KMID: 1482512
  • Hanyang Med Rev.
  • 2008 Aug;28(3):77-84.
In 2006, the annual number of Koreans traveling internationally increased to 11 million. With this increased number of Koreans traveling to developing countries, various infectious diseases have been reported to...
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Oral immunization of mice with recombinant rabies vaccine strain (ERAG3G) induces complete protection

Yang DK, Kim HH, Choi SS, Kim JT, Jeong WH, Song JY

PURPOSE: New rabies vaccine bait for both pets and raccoon dogs residing in Korea is needed to eradicate rabies infection among animals. In this study, we constructed a recombinant rabies...
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Application of recombinant adenoviruses expressing glycoprotein or nucleoprotein of rabies virus to Korean raccoon dogs

Choi J, Yang DK, Kim HH, Jo HY, Choi SS, Kim JT, Cho IS, Kim HW

PURPOSE: A new rabies vaccine for animals, including raccoon dogs, in Korea is needed to eradicate rabies infection. In this study, we constructed two recombinant adenoviruses expressing the glycoprotein or...
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Immunogenicity and efficacy of Rabivac vaccine for animal rabies control in Morocco

Darkaoui S, Fassi Fihri O, Schereffer JL, Aboulfidaa N, Wasniewski M, Zouine K, Bouslikhane M, Yahia KI, Cliquet F

PURPOSE: To fight animal rabies, Moroccan veterinary authorities organize annual dog mass vaccination campaigns using Rabivac vaccine, an inactivated adjuvanted cell culture veterinary rabies vaccine. Two experiments were undertaken to...
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First trials of oral vaccination with rabies SAG2 dog baits in Morocco

Darkaoui S, Boue F, Demerson J, Fassi Fihri O, Yahia KI, Cliquet F

PURPOSE: Canine rabies is a serious health problem in Morocco and about 22 human deaths are reported yearly. Following the World Health Organization (WHO) recommendations, Moroccan authorities evaluated oral rabies...
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Efficiency of Matricaria chamomilla CH(12) and number of doses of rabies vaccine on the humoral immune response in cattle

de Souza Reis LS, Frazatti-Gallina NM, de Lima Paoli R, Giuffrida , Albas A, Oba E, Pardo PE

This study evaluated the effect of Matricaria chamomilla and vaccination frequency on cattle immunization against rabies. Four groups (n = 15 /group) were treated with or without Matricaria chamomilla CH(12)...
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The Use of Orphan Drugs for Infectious Disease: Current Status and Unmet Needs

Kim MJ, Chang HH, Jin S, Park JH, Jung H, Lee HJ, Choi SH, Kim SW

BACKGROUND/AIMS: The aim of this study was to investigate the inconveniences and potential improvements in the use of orphan drugs for the treatment of infectious diseases, as determined by a...
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