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The Multiplex RT-PCR for the Serotyping of Hantaviruses

Lee PW, Park MS

  • KMID: 2099294
  • J Korean Soc Microbiol.
  • 1998 Oct;33(5):451-461.
Hantaviruses are negative-strand RNA viruses that contain three segmented genome and belong to the family Bunyaviridae. Due to such an unique structure of segmented RNA genome, these viruses have a...
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The Generation of Reassortants by Genetic Reassortment between Different Serotypes of Hantaviruses

Park MS, Chung DH, Lee PW

  • KMID: 1615426
  • J Bacteriol Virol.
  • 2003 Mar;33(1):69-80.
Hantaviruses are negative-strand RNA viruses that contain three segmented (L/M/S) genome and belong to the genus hantavirus of the family Bunyaviridae. Due to such an unique structure of segmented RNA...
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Original Antigenic Sin Response to RNA Viruses and Antiviral Immunity

Park MS, Kim JI, Park S, Lee I, Park MS

The human immune system has evolved to fight against foreign pathogens. It plays a central role in the body's defense mechanism. However, the immune memory geared to fight off a...
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A Metaviromic Analysis of Viral Communities in the Feces of Unexplained Acute Gastroenteritis

Baek IH, Kim SA, Kim JH, Park HK, Kim W

Although viruses are the most common cause of acute gastroenteritis (AGE) in humans, details about the causative viruses in AGE are largely unknown because many causative viruses are unable to...
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Rapid Whole-genome Sequencing of Zika Viruses using Direct RNA Sequencing

Kim JH, Kim J, Koo BS, Oh H, Hong JJ, Hwang ES

Zika virus (ZIKV) is one of the pathogens which is transmitted world widely, but there are no effective drugs and vaccines. Whole genome sequencing (WGS) of viruses could be applied...
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A Case of Allergic Contact Dermatitis to Ribavirin

Oh CW, Park MY, Hahm JH

Allergic contact dermatitis to topical agents mostly results from vehicles and preservatives and rarely from the active ingredients. Ribavirin, an active ingredient of Viramid® cream, is a synthetic nucleoside derivative...
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Hepatitis G virus

Jang SJ

  • KMID: 2425649
  • Korean J Clin Microbiol.
  • 1998 Sep;1(1):15-21.
Recently, two groups reported independently on the isolation of new positive-trand RNA viruses, designated hepatitis G virus (HGV) & GB virus C (GBV-C). Sequence analysis revealed that both genomes are...
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Intracellular Localization of the Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein

Yun SI, Choi YJ, Song BH, Kang SY, Lee YM

Porcine reproductive and respiratory syndrome virus (PRRSV) is a small enveloped, positive-stranded RNA virus belonging to the family Arteriviridae. It causes the porcine reproductive and respiratory syndrome in swine. The...
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Development of RT-PCR Method to Detect Various Human Enteric Viruses

Oh SA, Kim MS, Jang SY, Kim SJ, Lee JI, Lee GC, Lee CH

Human enteric viruses are one of the major causes of acute gastroenteritis outbreaks. A rapid and precise detection of virus is critical for prompt diagnosis. For this purpose, nucleic acid-based...
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MicroRNAs in Human Diseases: From Lung, Liver and Kidney Diseases to Infectious Disease, Sickle Cell Disease and Endometrium Disease

Ha TY

MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs of about 22 nucleotides that have recently emerged as important regulators of gene expression at the posttranscriptional level. Recent...
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Database construction of small–molecule inhibitors as bovine viral diarrhea virus (BVDV) RNA-dependent RNA polymerase: a cheminformatics approach

Chai HH, Choi BH, Park JE, Kim UH, Cho YM, Lim D

Bovine viral diarrhea virus (BVDV) is a major pathogen that may be one of the main reasons for economic losses in the livestock industry. BVDV is a well-characterized member of...
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Genomic Diversity of Human Rotaviruses, a Cause of Diarrhea in Korean Children: 1989-1994

Kim H, Kim K, Kim J, Cho Y, Kim D, Choi T

  • KMID: 1943467
  • J Korean Soc Microbiol.
  • 1997 Apr;32(2):237-244.
Rotaviruses (Rv) have been recognized as one of the most important agents causing severe viral gastroenteritis in young children and newborn animals throughout the world. The fact that Rv possess...
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Inflammasomes in antiviral immunity: clues for influenza vaccine development

Yamazaki T, Ichinohe T

Inflammasomes are cytosolic multiprotein complexes that sense microbial motifs or cellular stress and stimulate caspase-1-dependent cytokine secretion and cell death. Recently, it has become increasingly evident that both DNA and...
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Towards the Application of Human Defensins as Antivirals

Park MS, Kim JI, Lee I, Park S, Bae JY, Park MS

Defensins are antimicrobial peptides that participate in the innate immunity of hosts. Humans constitutively and/or inducibly express α- and β-defensins, which are known for their antiviral and antibacterial activities. This...
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Detection of Human Cytomegalovirus (HCMV) and Porcine Endogenous Retrovirus (PERV) with One Step Extraction Method

Kim JH, Jung ES, Hwang ES

BACKGROUND: Xenotransplantation is thought to be one of the alternative methods to overcome the shortage of human organs for transplantation. Recipients should be immunosuppressed for graft survival, and thus, there...
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Newcastle disease virus vectored vaccines as bivalent or antigen delivery vaccines

Choi KS

Recent advances in reverse genetics techniques make it possible to manipulate the genome of RNA viruses such as Newcastle disease virus (NDV). Several NDV vaccine strains have been used as...
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Polymorphism Analysis of Hepatitis G Virus ( HGV ) Based on RT-PCR and RFLP

Park YS, Joo EM

  • KMID: 1540642
  • J Korean Soc Microbiol.
  • 1997 Oct;32(5):593-600.
Hepatitis G virus (HGV) is a single-strand RNA virus in the Flaviviridae family, it was recently identified from the plasma of a patient with chronic hepatitis. HOV infection may cause...
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Human rhinoviruses and asthma in children

Kim WK

Human rhinoviruses (HRVs) is a nonenveloped, single stranded RNA virus belonging to the family Picornavirudae. Transmission by direct contact such as hand-to-hand, hand-to-nose, and hand-to-eye has been readily demonstrated in...
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A Clinical Study of Ribavirin (Virazole) in Herpes Zoster

Sung KJ, Kim KJ, Cinn YW, Kim WS, Kim HS, Lee YS

  • KMID: 1678128
  • Korean J Dermatol.
  • 1980 Dec;18(6):573-577.
Ribavirin(l-b-D-ribofuranosyl-l, 2, 4-triazole-3-carboximide, Virazole) is a. synthetic nucleoside derivative with reported broad spectrum activity in vitro and in vivo against a wide variety of DNA and RNA viruses. This drug...
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Hepatitis A Vaccine

Jeong SH

  • KMID: 1482504
  • Hanyang Med Rev.
  • 2008 Aug;28(3):16-23.
Hepatitis A virus (HAV) is a RNA virus classified within Picornaviridae family HAV vaccines containing formalin-inactivated virus produced in cell culture have been licensed in the early 1990s. HAV seroepidemiology...
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